Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 5565
TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372303BDBM372303(3-(3-chloro-2-fluoro-6-((2,2,7-trifluorobenzo[d][1...)
Affinity DataIC50: 0.640nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372315BDBM372315(3-(3,4-dichloro-2-fluoro-6-((2,2,7-trifluorobenzo[...)
Affinity DataIC50: 0.710nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372307BDBM372307(5-(3,4-Dichloro-2-fluoro-6-(4-(trifluoromethoxy)ph...)
Affinity DataIC50: 0.980nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372313BDBM372313(5-(3-chloro-6-(4,5-difluoro-2-(methoxy-d3)phenoxy)...)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372305BDBM372305(3-(5-chloro-4-(trifluoromethyl)-2-(4- (trifluorome...)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372316BDBM372316(5-(3-chloro-2-fluoro-6-(4-fluoro-2-methylphenoxy)-...)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372311BDBM372311(5-(4,5-dichloro-2-(2-(methoxy-d3)-4-(trifluorometh...)
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372306BDBM372306(5-(4,5-dichloro-2-(2-methoxy-4-(trifluoromethoxy)p...)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372312BDBM372312(5-(3-Chloro-6-(4-(difluoromethoxy)phenoxy)-2-fluor...)
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372310BDBM372310(3-(5-chloro-2-((2,2,7-trifluorobenzo[d][1,3]dioxol...)
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372320BDBM372320(3-(4,5-dichloro-2-(4-(trifluoromethoxy)phenoxy-2- ...)
Affinity DataIC50: 6.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372317BDBM372317(3-(4,5-dichloro-2-(4-(trifluoromethoxy)phenoxy-3- ...)
Affinity DataIC50: 7.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372319BDBM372319(3-(4,5-dichloro-2-(4-(trifluoromethoxy)phenoxy-3,5...)
Affinity DataIC50: 7.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372309BDBM372309(3-(4,5-dichloro-2-((2,2,7-trifluorobenzo[d][1,3]di...)
Affinity DataIC50: 8.15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372322BDBM372322(3-(4,5-dichloro-2-(4-(trifluoromethoxy)phenoxy-2,6...)
Affinity DataIC50: 8.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372314BDBM372314(5-(5-chloro-2-(4-fluoro-2-methylphenoxy)-4-(triflu...)
Affinity DataIC50: 9.75nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372304BDBM372304(3-(3-chloro-2-fluoro-6-((3,3,6,7-tetrafluoro-2,3- ...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372302BDBM372302(5-(5-chloro-2-(4-(trifluoromethoxy)phenoxy)-4-(tri...)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 372301BDBM372301(5-(4,5-dichloro-2-(4-(trifluoromethoxy)phenoxy)ben...)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent