UniProt Accession IDs for Pathway Drug-mediated inhibition of CDK4/CDK6 activity

The UniProt or TrEMBL identifiers listed in this pages are extracted from UniProt2Reactome_All_Levels.txt, whose links of the affinity data in BindingDB are also listed.

  1. Primary ID
    UniProt Recommended Name
    Secondary IDs
    BindingDB Name
    Affinity Link(s)
    Articles
    Downloads
  2. P24385
    G1/S-specific cyclin-D1
    Q6LEF0
    G1/S-specific cyclin-D1
    IC50: 10
    1
    2D 3D TSV
  3. P24385
    G1/S-specific cyclin-D1
    Q6LEF0
    Cyclin-dependent kinase 2/G1/S-specific cyclin-D1
    IC50: 7
    1
    2D 3D TSV
  4. P24385
    G1/S-specific cyclin-D1
    Q6LEF0
    Cyclin-dependent kinase 6/G1/S-specific cyclin-D1
    Ki: 17 IC50: 347
    31
    2D 3D TSV
  5. P24385
    G1/S-specific cyclin-D1
    Q6LEF0
    Cyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C]
    Ki: 201 IC50: 10
    4
    2D 3D TSV
  6. P24385
    G1/S-specific cyclin-D1
    Q6LEF0
    Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C]
    IC50: 229
    9
    2D 3D TSV
  7. P24385
    G1/S-specific cyclin-D1
    Q6LEF0
    Cyclin-dependent kinase 4/G1/S-specific cyclin-D1
    Ki: 460 IC50: 2590 Kd: 2 EC50: 2
    157
    2D 3D TSV
  8. P24385
    G1/S-specific cyclin-D1
    Q6LEF0
    ...
    Ki: 678 IC50: 3193 Kd: 2 EC50: 2
    175
    2D 3D TSV
  9. Q00534
    Cyclin-dependent kinase 6
    A4D1G0
    Cyclin-dependent kinase 6
    Ki: 3 IC50: 1042 Kd: 2
    65
    2D 3D TSV
  10. Q00534
    Cyclin-dependent kinase 6
    A4D1G0
    Cyclin-dependent kinase 6/G1/S-specific cyclin-D1
    Ki: 17 IC50: 347
    31
    2D 3D TSV
  11. Q00534
    Cyclin-dependent kinase 6
    A4D1G0
    Cyclin-dependent kinase 4/6
    IC50: 120
    3
    2D 3D TSV
  12. Q00534
    Cyclin-dependent kinase 6
    A4D1G0
    Cyclin-dependent kinase 6/G1/S-specific cyclin-D3
    Ki: 399 IC50: 798 Kd: 1
    65
    2D 3D TSV
  13. Q00534
    Cyclin-dependent kinase 6
    A4D1G0
    Cyclin-dependent kinase 6/G1/S-specific cyclin-D1
    Ki: 398 IC50: 176
    4
    2D 3D TSV
  14. Q00534
    Cyclin-dependent kinase 6
    A4D1G0
    Cyclin homolog/dependent kinase 6
    IC50: 7
    1
    2D 3D TSV
  15. Q00534
    Cyclin-dependent kinase 6
    A4D1G0
    Cyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C]
    Ki: 201 IC50: 10
    4
    2D 3D TSV
  16. Q00534
    Cyclin-dependent kinase 6
    A4D1G0
    ...
    Ki: 1018 IC50: 2500 Kd: 3
    160
    2D 3D TSV