UniProt Accession IDs for Pathway GRB2:SOS provides linkage to MAPK signaling for Integrins

The UniProt or TrEMBL identifiers listed in this pages are extracted from UniProt2Reactome_All_Levels.txt, whose links of the affinity data in BindingDB are also listed.

  1. Primary ID
    UniProt Recommended Name
    Secondary IDs
    BindingDB Name
    Affinity Link(s)
    Articles
    Downloads
  2. P05106
    Integrin beta-3
    A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499
    Integrin alpha-3/beta-3
    IC50: 47
    1
    2D 3D TSV
  3. P05106
    Integrin beta-3
    A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499
    Integrin alpha-V/beta-3/beta-5
    IC50: 8
    1
    2D 3D TSV
  4. P05106
    Integrin beta-3
    A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499
    Integrin alpha-IIb/beta-3
    Ki: 203 IC50: 2638 Kd: 115 EC50: 21
    148
    2D 3D TSV
  5. P05106
    Integrin beta-3
    A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499
    Integrin alpha-2/beta-3
    IC50: 31
    3
    2D 3D TSV
  6. P05106
    Integrin beta-3
    A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499
    Integrin alpha-V/beta-3
    Ki: 228 IC50: 2042 Kd: 5 EC50: 23
    145
    2D 3D TSV
  7. P05106
    Integrin beta-3
    A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499
    ...
    Ki: 431 IC50: 4766 Kd: 120 EC50: 44
    225
    2D 3D TSV
  8. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    Son of sevenless homolog 1
    Ki: 33 IC50: 626 Kd: 196 EC50: 167
    18
    2D 3D TSV
  9. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    Son of sevenless homolog 1 [564-1049]
    Ki: 306 IC50: 503 Kd: 234
    3
    2D 3D TSV
  10. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    KRas/Son of Sevenless Homolog 1
    IC50: 70
    1
    2D 3D TSV
  11. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    GTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049]
    IC50: 26
    1
    2D 3D TSV
  12. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    KRAS (G12D)/Son of Sevenless Homolog 1 (SOS)/RAF Proto-Oncogene Serine/Threonine-Protein Kinase (c-Raf)
    IC50: 21
    1
    2D 3D TSV
  13. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    GTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)
    IC50: 1914
    3
    2D 3D TSV
  14. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    GTPase KRas [1-169,G12C,C118A]/Son of sevenless homolog 1 [564-1049]
    IC50: 696
    1
    2D 3D TSV
  15. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    KRas [G12V]/Son of Sevenless Homolog 1
    IC50: 70
    1
    2D 3D TSV
  16. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    version 2 g12v
    IC50: 237
    2
    2D 3D TSV
  17. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    GTPase KRas [Q61H]/Son of sevenless homolog 1
    IC50: 3
    1
    2D 3D TSV
  18. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    version 2 g12d
    IC50: 458
    3
    2D 3D TSV
  19. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    GTPase KRAS G12V (1-169)
    IC50: 932
    6
    2D 3D TSV
  20. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    Son of sevenless homolog 1/GTPase KRas [G12C]
    IC50: 2016
    7
    2D 3D TSV
  21. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    GTPase KRas [2-169,G12C]/Son of sevenless homolog 1 [564-1049]
    IC50: 25
    1
    2D 3D TSV
  22. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    GTPase KRas [1-169,G12D]/Son of sevenless homolog 1 [564-1049]
    IC50: 315
    3
    2D 3D TSV
  23. Q07889
    Son of sevenless homolog 1
    A8K2G3 B4DXG2
    ...
    Ki: 339 IC50: 7999 Kd: 460 EC50: 167
    47
    2D 3D TSV