Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

TargetApolipoprotein L1(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 615214BDBM615214(3-[2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(3R,4S)-4-...)
Affinity DataIC50: 5.25E+4nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent