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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
1
hit in this display
Target
Apolipoprotein L1
(Human)
Vertex Pharmaceuticals
US Patent
Ligand
BDBM615214
(3-[2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(3R,4S)-4-...)
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Affinity Data
IC50: 5.25E+4nM
Assay Description:
Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/15/2023
Entry Details
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US Patent
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