Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetAlpha-2A adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50027028BDBM50027028(2-(piperazin-1-yl)nicotinamide | 2-Piperazin-1-yl-...)
Affinity DataKi:  5.20E+3nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50027028BDBM50027028(2-(piperazin-1-yl)nicotinamide | 2-Piperazin-1-yl-...)
Affinity DataKi:  6.20E+4nMAssay Description:Binding activity against alpha-1 adrenergic receptor from calf cerebral cortex, using [3H]-prazosin as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcidic mammalian chitinase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50027028BDBM50027028(2-(piperazin-1-yl)nicotinamide | 2-Piperazin-1-yl-...)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of acidic mammalian chitinase after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetAcidic mammalian chitinase(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50027028BDBM50027028(2-(piperazin-1-yl)nicotinamide | 2-Piperazin-1-yl-...)
Affinity DataKd:  1.41E+5nMAssay Description:Binding affinity to biotinylated-acidic mammalian chitinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed