Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetAdenosine receptor A2a(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 479528BDBM479528(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-N-...)
Affinity DataIC50: 2.90nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 479528BDBM479528(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-N-...)
Affinity DataIC50: 2.90nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 479528BDBM479528(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-N-...)
Affinity DataIC50: 3.70nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 479528BDBM479528(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-N-...)
Affinity DataIC50: 3.70nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 479528BDBM479528(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-N-...)
Affinity DataIC50: 116nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 479528BDBM479528(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-N-...)
Affinity DataIC50: 116nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 479528BDBM479528(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-N-...)
Affinity DataIC50: 156nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 479528BDBM479528(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-N-...)
Affinity DataIC50: 156nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent