Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 33 hits for monomerid = 92900,92903,235688,235689,50049254,50375814,50375815,92900,92903,235688,235689,50049254,50375814,50375815   

TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM92900(L-Arginine, 2 | CHEMBL1835117 | NMMA, 2)
Affinity DataIC50: 650nMAssay Description:Inhibition of human recombinant eNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM92900(L-Arginine, 2 | CHEMBL1835117 | NMMA, 2)
Affinity DataIC50: 950nMAssay Description:Inhibition of human recombinant nNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM92900(L-Arginine, 2 | CHEMBL1835117 | NMMA, 2)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant iNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM92900(L-Arginine, 2 | CHEMBL1835117 | NMMA, 2)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetArginase-1(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50375814(CHEMBL260628)
Affinity DataKi:  1.71E+4nMAssay Description:Inhibition of bovine liver arginaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Université

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was evaluated for inhibitory activity against iNOS obtained from RAW 264.7 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University

LigandPNGBDBM235689(hDDAH inhibitor, 2c)
Affinity DataKi:  5.80E+4nM ΔG°:  -6.01kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University

LigandPNGBDBM235688(hDDAH inhibitor, 2b)
Affinity DataKi:  9.00E+4nM ΔG°:  -5.74kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetArginase-1(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50375814(CHEMBL260628)
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of bovine liver arginaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University

LigandPNGBDBM92900(L-Arginine, 2 | CHEMBL1835117 | NMMA, 2)
Affinity DataKi:  1.31E+5nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University

LigandPNGBDBM92900(L-Arginine, 2 | CHEMBL1835117 | NMMA, 2)
Affinity DataKi:  2.90E+5nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
The University of Texas

LigandPNGBDBM92903(L-Citrulline, 4)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University

LigandPNGBDBM92900(L-Arginine, 2 | CHEMBL1835117 | NMMA, 2)
Affinity DataKi:  1.20E+6nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataKi:  1.40E+6nMAssay Description:Binding affinity towards inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University

LigandPNGBDBM92900(L-Arginine, 2 | CHEMBL1835117 | NMMA, 2)
Affinity DataKi:  1.40E+6nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50375814(CHEMBL260628)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of human recombinant eNOS by griess assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50375814(CHEMBL260628)
Affinity DataIC50: 2.40E+6nMAssay Description:Inhibition of human recombinant iNOS by griess assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50375814(CHEMBL260628)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition of human recombinant nNOS by griess assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University

LigandPNGBDBM92903(L-Citrulline, 4)
Affinity DataKi:  3.70E+6nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50375815(CHEMBL408088)
Affinity DataIC50: 4.00E+6nMAssay Description:Inhibition of human recombinant eNOS by griess assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University

LigandPNGBDBM50375814(CHEMBL260628)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human recombinant DDAH1 expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University

LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human recombinant DDAH1 expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50375815(CHEMBL408088)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human recombinant iNOS by griess assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University

LigandPNGBDBM50375815(CHEMBL408088)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human recombinant DDAH1 expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50375815(CHEMBL408088)
Affinity DataIC50: 7.90E+6nMAssay Description:Inhibition of human recombinant nNOS by griess assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human recombinant eNOS by griess assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human recombinant nNOS by griess assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50049254(N(5)-carbamimidoyl-N(5)-methyl-L-ornithine | N(5)-...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human recombinant iNOS by griess assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM92900(L-Arginine, 2 | CHEMBL1835117 | NMMA, 2)
Affinity DataAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University

LigandPNGBDBM92900(L-Arginine, 2 | CHEMBL1835117 | NMMA, 2)
Affinity DataAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed