SMILES for Eukaryotic translation initiation factor 4E-binding protein 1

OC(=O)C1CC(C1)c1nc2cncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1 |(5.61,-5.16,;4.28,-5.93,;4.28,-7.47,;2.94,-5.16,;1.46,-5.56,;1.06,-4.08,;2.55,-3.68,;-.28,-3.31,;-1.61,-4.08,;-2.94,-3.31,;-4.28,-4.08,;-5.61,-3.31,;-5.61,-1.77,;-4.28,-1,;-4.28,.54,;-4.28,2.08,;-2.94,-1.77,;-1.61,-1,;-1.61,.54,;-.28,-1.77,;1.06,-1,;1.06,.54,;2.39,1.31,;2.39,2.85,;3.72,3.62,;3.72,5.16,;2.39,5.93,;2.39,7.47,;1.06,5.16,;1.06,3.62,)|

BDBM544669

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1O[C@@H]1CCC[C@@H]1n1cnc2cncc(C#N)c2c1=O |r|

BDBM544670

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)C(F)F

BDBM544671

Cc1nc2cc(nc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)C(F)(F)F

BDBM544672

Cc1nc2cncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(C(O)=O)c1C#C

BDBM544673

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(C(O)=O)c1C#C)C(F)(F)F

BDBM544674

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccc(C(O)=O)c(c1)C(O)=O)C(F)(F)F

BDBM544675

OC(=O)c1cccc(-c2cc(Cl)ccc2OCCn2cnc3cc(cc(C#N)c3c2=O)C(F)(F)F)c1C#C

BDBM544676

Cc1nc2ccc(C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544677

OC(=O)c1cc(ccn1)-c1cc(Cl)ccc1OCCn1cnc2ccc(C(F)F)c(C#N)c2c1=O

BDBM544678

OC(=O)c1cc(ccn1)-c1cc(Cl)ccc1OCCn1cnc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM544679

OC(=O)c1nccc(-c2cc(Cl)ccc2OCCn2c(nc3cccc(C#N)c3c2=O)C(F)F)c1C#C

BDBM544680

OC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1cnc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM544681

OC(=O)c1cccc(-c2cc(Cl)ccc2OCCn2c(nc3cccc(C#N)c3c2=O)C(F)F)c1C#C

BDBM544682

OC(=O)c1cc(ccn1)-c1cc(Cl)ccc1OCCn1c(nc2cccc(C#N)c2c1=O)C(F)F

BDBM544683

Cc1nc2cc(F)cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O

BDBM544684

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(C(O)=O)c1C#N)C(F)(F)F

BDBM544685

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(C(O)=O)c1C=C)C(F)(F)F

BDBM544686

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCc1cccc2nc[nH]c(=O)c12

BDBM544687

CNc1nc2c(F)ccc(CCOc3ccc(Cl)cc3-c3cccc(c3)C(O)=O)c2c(=O)[nH]1

BDBM544688

CNc1nc2c(F)c(F)cc(CCOc3ccc(Cl)cc3-c3cccc(c3)C(O)=O)c2c(=O)[nH]1

BDBM544689

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCc1cnc(C(F)F)c2nc(Nc3ccccc3)[nH]c(=O)c12

BDBM544690

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCc1cc(F)c(C#N)c2nc(Nc3ccccc3)[nH]c(=O)c12

BDBM544691

OC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1cc(C#N)c2nc(Nc3ccccc3)[nH]c(=O)c12

BDBM544692

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCc1ccnc2nc(Nc3ccccc3)[nH]c(=O)c12

BDBM544693

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCc1cnc(C#N)c2nc(NCC(F)(F)F)[nH]c(=O)c12

BDBM544694

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCc1cc(nc2nc(Nc3ccccc3)[nH]c(=O)c12)C(F)(F)F

BDBM544695

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCc1cnc(C#N)c2nc(Nc3ccccc3)[nH]c(=O)c12

BDBM544696

Cc1c(CCOc2ccc(Cl)cc2-c2ccnc3c(csc23)C(O)=O)c(=O)c2c(cc(cc2n1C)C(F)(F)F)C#N

BDBM544697

OC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(CF)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM544698

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(CF)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM544699

CC(C)c1nc(N2CCN(CCF)CC2)c(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM544700

OCC(O)CCCCc1cc(ccc1C(O)=O)-c1cc(Cl)ccc1OCCn1cnc2cncc(C#N)c2c1=O

BDBM544701

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(nc2cc(cc(C#N)c2c1=O)C(F)(F)F)C#N

BDBM544702

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(O)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM544703

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(Cl)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM544704

OC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(nc2ccc(C(F)F)c(C#N)c2c1=O)C(F)F

BDBM544705

OC(=O)c1csc2c(nccc12)-c1cc(Cl)ccc1OCCn1c(nc2cccc(C#N)c2c1=O)C(F)F

BDBM544706

OC(=O)c1ccc(-c2cc(Cl)ccc2OCCn2c(nc3cccc(C#N)c3c2=O)C(F)F)c2sncc12

BDBM544707

OC(=O)c1ccc(-c2cc(Cl)ccc2OCCn2c(nc3cccc(C#N)c3c2=O)C(F)F)c2sccc12

BDBM544708

OC(=O)Cn1cncc(-c2cc(Cl)ccc2OCCn2c(nc3cccc(C#N)c3c2=O)C(F)F)c1=S

BDBM544709

CN(C)S(=O)(=O)c1cc(C#N)c2c(c1)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM544710

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(C)(=O)=O

BDBM544711

Cc1nc2ccc(c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(C)(=O)=O

BDBM544712

CN(C)S(=O)(=O)c1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544713

Cc1nc2c(cc(C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C#N

BDBM544714

Cc1nc2cc(cc(Cl)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544715

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2cc(sc12)C(O)=O)C(F)(F)F

BDBM544716

Cc1nc2cc(Cl)cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544717

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cc(nc2ccsc12)C(O)=O)C(F)(F)F

BDBM544718

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(CC(O)=O)csc12)C(F)(F)F

BDBM544719

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1csc2c(csc12)C(O)=O)C(F)(F)F

BDBM544720

Cc1nc2c(ccc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)-c1cncnc1

BDBM544721

Cc1sc2c(ccnc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM544722

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(C(O)=O)c(C=C)sc12)C(F)(F)F

BDBM544723

Cc1nc2cc(Cl)c(Cl)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544724

Cc1nc2cc(Cl)c(Cl)c(Cl)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544725

Cc1nc2c(Cl)cc(Cl)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544726

Cc1nc2c(C#N)c(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544727

Cc1nc2c(ccc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C#C

BDBM544728

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C#N

BDBM544729

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C#C

BDBM544730

Cc1nc2cc(c(C#N)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544731

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ncnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544732

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)c1ccncc1

BDBM544733

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(C)(F)F

BDBM544734

Cc1c(Cl)c2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544735

Cc1nc2cc(cc(c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F)C(F)(F)F

BDBM544736

Cc1nc2cc(cc(C(F)F)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544737

Cc1nc2cc(cc(S)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544738

CSc1cc(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c12)C(F)(F)F

BDBM544739

Cc1nc2cc(cc(c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(C)(=O)=O)C(F)(F)F

BDBM544740

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)N(=O)=O

BDBM544741

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1nccc2c(csc12)C(O)=O)C(F)(F)F

BDBM544742

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccc(C(O)=O)c2ncsc12)C(F)(F)F

BDBM544743

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccccc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544744

Cc1nc2ccc(C#N)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544745

Cc1nc2c(ccc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(C)(=O)=O

BDBM544746

Cc1nc2cc(F)c(C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544747

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(CF)nc2cc(cc(C#N)c2c1=O)C#N

BDBM544748

OC(=O)c1cccc(-c2cc(Cl)ccc2OCCn2c(CF)nc3cc(cc(C#N)c3c2=O)C#N)c1C#C

BDBM544749

CS(=O)(=O)c1cc(C#N)c2c(c1)nc(CF)n(CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)c2=O

BDBM544752

Cc1nc2ccc(OC(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544753

CN(C)S(=O)(=O)c1ccc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM544754

CNS(=O)(=O)c1ccc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM544755

Cc1nc2cc(C#N)c(Cl)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544756

Cc1nc2cc(C#N)c(F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544757

Cc1nc2c(F)cc(F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544758

Cc1nc2cc(Cl)c(F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544759

Cc1nc2cc(F)c(Cl)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544760

Cc1nc2ccc(Cl)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544761

Cc1nc2ccc(F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544762

Cc1nc2cc(c(F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544763

CN(C)S(=O)(=O)c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544764

Cc1nc2ccc(c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(=O)(=O)N1CCC1

BDBM544765

Cc1nc2ccc(c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(=O)(=O)N1CCCC1

BDBM544766

CCN(CC)S(=O)(=O)c1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544767

Cc1nc2ccc(c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(=O)(=O)N1CCCCC1

BDBM544768

Cc1nc2ccc(c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(=O)(=O)NCc1ccccc1

BDBM544769

CCN(Cc1ccccc1)S(=O)(=O)c1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544770

Cc1nc2cccc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544771

Cc1nc2cc(cc(C#N)c2c(=O)n1C\C=C\c1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544772

Cc1nc2cc(Cl)c(Cl)c(C#N)c2c(=O)n1C\C=C\c1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544773

Cc1nc2cc(Cl)c(Cl)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544774

Cc1nc2cc(cc(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C#N

BDBM544775

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ncc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544776

Cc1nc2cnc(C3CCC(F)(F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544777

CN(C)Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM544779

Cc1c(C#N)c2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544780

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)Cl

BDBM544781

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1snc2c(csc12)C(O)=O)C(F)(F)F

BDBM544782

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(C(O)=O)c(Cl)sc12)C(F)(F)F

BDBM544783

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(C(O)=O)c(sc12)C#C)C(F)(F)F

BDBM544784

Cc1c(c2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F)C(F)(F)F

BDBM544785

Cc1c(C(F)F)c2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544786

Cc1c([N+](O)=O)c2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544787

Cc1nc2cc(cc(c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)N(=O)=O)C(F)(F)F

BDBM544789

Cc1c(F)c2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C#N

BDBM544790

Cc1c(F)c2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(C)(=C)=O

BDBM544791

CCc1cccc(n1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM544792

Cc1nc2cc(F)c(C#N)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544793

Cc1nc2cc(c(Cl)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(C)(=O)=O

BDBM544794

Cc1nc2cc(c(F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(C)(=O)=O

BDBM544795

Cc1nc2cc(F)c(c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(C)(=O)=O

BDBM544796

CN(C)S(=O)(=O)c1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1F

BDBM544797

CN(C)S(=O)(=O)c1c(F)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544798

Cc1nc2ccc(c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(=O)(=O)N1CCC(F)(F)CC1

BDBM544799

CN(Cc1ccccc1)S(=O)(=O)c1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544800

Cc1nc2c(ncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C1CCC(F)(F)CC1

BDBM544801

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccncc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544802

Cc1nc2cc(cc(C#N)c2c(=O)n1C\C=C\c1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C#N

BDBM544803

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(cc1-c1ccnc2c(csc12)C(O)=O)C#N)C(F)(F)F

BDBM544804

CN(C)S(=O)(=O)c1cc(F)c2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544805

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1cc(F)c(cc1-c1ccnc2c(csc12)C(O)=O)C#N)C(F)(F)F

BDBM544806

Cc1nc2cc(Cl)c(Cl)c(C#N)c2c(=O)n1CCOc1ccc(cc1-c1ccnc2c(csc12)C(O)=O)C#N

BDBM544807

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1cnc(cc1-c1ccnc2c(csc12)C(O)=O)C#N)C(F)(F)F

BDBM544808

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(nc1-c1ccnc2c(csc12)C(O)=O)C#N)C(F)(F)F

BDBM544809

Cc1nc2c(F)cc(c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(C)(=O)=O

BDBM544810

Cc1nc2c(F)c(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544811

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(F)(F)C(O)=O)C(F)(F)F

BDBM544813

Cc1nc2ccc(c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(=O)(=O)c1ccccn1

BDBM544814

Cc1nc2c(F)c(F)c(C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544815

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1csc2c(ccnc12)C(O)=O)C(F)(F)F

BDBM544816

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1coc2c(cccc12)C(O)=O)C(F)(F)F

BDBM544817

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1csc2c(cccc12)C(O)=O)C(F)(F)F

BDBM544818

Cc1nc2c(F)cc(C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)-c1nnn[nH]1

BDBM544819

CONC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(C)nc2c(F)cc(C(F)F)c(C#N)c2c1=O

BDBM544820

Cc1nc2cc(cc(Br)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)C(F)(F)F

BDBM544821

Cc1nc2cc(cc(Br)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544822

Cc1nc2cc(F)c(F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)-c1nnn[nH]1

BDBM544823

Cc1nc2cc(F)c(F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O

BDBM544824

CONC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(F)c(F)c(C#N)c2c1=O

BDBM544825

COc1c(C)n(CCOc2ccc(Cl)cc2-c2ccnc3c(csc23)C(O)=O)c(=O)c2c(cc(cc12)C(F)(F)F)C#N

BDBM544826

Cc1c(O)c2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544827

CN(C)Cc1c(F)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544828

Cc1nc2c(ccc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C#N

BDBM544829

Cc1nc2c(OC(F)(F)F)ccc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544830

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cnnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544831

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1nsc2c(csc12)C(O)=O)C(F)(F)F

BDBM544832

Cc1nc2ccc(C(N)=O)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544833

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(N)=O

BDBM544834

Cc1c(c2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F)S(C)(=O)=O

BDBM544835

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cncc2c(csc12)C(O)=O)C(F)(F)F

BDBM544836

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(cn(C)c12)C(O)=O)C(F)(F)F

BDBM544837

Cc1nc2cc(c(CC3CN(CCF)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544838

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc2c(c[nH]c12)C(O)=O)C(F)(F)F

BDBM544839

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(c[nH]c12)C(O)=O)C(F)(F)F

BDBM544840

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1coc2c(ccnc12)C(O)=O)C(F)(F)F

BDBM544841

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(coc12)C(O)=O)C(F)(F)F

BDBM544842

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1N1CCC(CC1)C(O)=O)C(F)(F)F

BDBM544843

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc2C(=CS(=O)(=O)c12)C(O)=O)C(F)(F)F |c:32|

BDBM544844

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1N1CCC(CC(O)=O)CC1)C(F)(F)F

BDBM544845

COc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544846

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544847

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cc(=O)n(C)c2c(csc12)C(O)=O)C(F)(F)F

BDBM544848

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2c1F

BDBM544849

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc4CNCCc4c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544850

CN1CCc2c(C1)cc1nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c1c2C#N

BDBM544851

CN1CCc2cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c(C#N)c2C1

BDBM544852

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(cnc3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544853

CCc1ncc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM544854

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(ncc(C#N)c3c2=O)C2CC2)c2scc(C(O)=O)c2n1

BDBM544855

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(ncc(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544856

Cc1cc(ccn1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM544857

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cncc(F)c4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544858

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cnccc4F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(9.34,2.69,;8,1.93,;6.67,2.7,;5.33,1.93,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.93,;2.67,.38,;1.33,-.38,;1.33,-1.93,;,-2.69,;,-4.23,;1.33,-5,;-1.33,-5,;-2.67,-4.23,;-4,-5,;-5.33,-4.23,;-5.33,-2.69,;-6.67,-1.92,;-8,-2.69,;-9.34,-1.92,;-9.34,-.38,;-8,.39,;-6.67,-.38,;-5.33,.38,;-4,-1.93,;-4,-.38,;-4,1.15,;-2.67,-2.69,;-1.33,-1.93,;-1.33,-.38,;-6.67,-5,;-8,-4.23,;-6.67,-6.54,;-8,-5.78,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.38,;8,.38,)|

BDBM544859

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccncc4F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(9.34,2.69,;8,1.93,;6.67,2.7,;5.33,1.93,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.93,;2.67,.38,;1.33,-.38,;1.33,-1.93,;,-2.69,;,-4.23,;1.33,-5,;-1.33,-5,;-2.67,-4.23,;-4,-5,;-5.33,-4.23,;-5.33,-2.69,;-6.67,-1.92,;-8,-2.69,;-9.34,-1.92,;-9.34,-.38,;-8,.39,;-6.67,-.38,;-5.33,.38,;-4,-1.93,;-4,-.38,;-4,1.15,;-2.67,-2.69,;-1.33,-1.93,;-1.33,-.38,;-6.67,-5,;-8,-4.23,;-6.67,-6.54,;-8,-5.78,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.38,;8,.38,)|

BDBM544860

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2ccccc2C#N)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544861

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2ccccc2C(N)=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544862

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2ccccc2CO)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544863

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cnsc4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544864

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccns4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544865

Cc1ccc(c(C)n1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-10,.38,;-8.67,-.38,;-8.67,-1.93,;-7.34,-2.7,;-6,-1.93,;-6,-.38,;-4.67,.38,;-7.34,.38,;-4.67,-2.69,;-4.67,-4.23,;-3.33,-5,;-2,-4.23,;-.67,-5,;.67,-4.23,;2,-5,;.67,-2.69,;2,-1.93,;2,-.38,;3.33,.38,;3.33,1.93,;2,2.69,;2,4.23,;3.33,5,;3.33,6.54,;4.67,4.23,;4.67,2.69,;6,1.93,;7.34,2.7,;8.67,1.93,;10,2.69,;8.67,.38,;7.34,-.38,;7.02,-1.89,;5.48,-2.05,;4.86,-.65,;6,.38,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;-.67,-1.93,;-.67,-.38,;-2,-2.69,;-3.33,-1.93,;-3.33,-.38,;-3.33,1.15,;-6,-5,;-7.34,-4.23,;-6,-6.54,;-7.34,-5.78,)|

BDBM544866

Cc1cc(C)c(cn1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-10,.38,;-8.67,-.38,;-7.34,.38,;-6,-.38,;-4.67,.38,;-6,-1.93,;-7.34,-2.7,;-8.67,-1.93,;-4.67,-2.69,;-4.67,-4.23,;-3.33,-5,;-2,-4.23,;-.67,-5,;.67,-4.23,;2,-5,;.67,-2.69,;2,-1.93,;2,-.38,;3.33,.38,;3.33,1.93,;2,2.69,;2,4.23,;3.33,5,;3.33,6.54,;4.67,4.23,;4.67,2.69,;6,1.93,;7.34,2.7,;8.67,1.93,;10,2.69,;8.67,.38,;7.34,-.38,;7.02,-1.89,;5.48,-2.05,;4.86,-.65,;6,.38,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;-.67,-1.93,;-.67,-.38,;-2,-2.69,;-3.33,-1.93,;-3.33,-.38,;-3.33,1.15,;-6,-5,;-7.34,-4.23,;-6,-6.54,;-7.34,-5.78,)|

BDBM544867

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(cc(O)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544868

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(ccc3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544869

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(C)(C)O)C(F)(F)F

BDBM544870

Cn1cc(CCOc2ccc(Cl)cc2-c2ccnc3c(csc23)C(O)=O)c(=O)c2c(cc(cc12)C(F)(F)F)C#N

BDBM544871

COc1nc(OCCn2c(C)nc3cc(cc(C#N)c3c2=O)C(F)(F)F)c(cc1Cl)-c1ccnc2c(csc12)C(O)=O

BDBM544872

CN1c2cc(cc(C#N)c2C(=O)N(CCOc2ccc(Cl)cc2-c2ccnc3c(csc23)C(O)=O)C1(C)C)C(F)(F)F

BDBM544873

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1[nH]c(=O)c(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544875

Cc1nc2c(ccc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544876

Cc1nc2c(OC(F)F)ccc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544877

Cc1nc2c(ccc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)F

BDBM544878

Cc1c(CCOc2ccc(Cl)cc2-c2ccnc3c(csc23)C(O)=O)c(=O)c2c(C#N)c(Cl)c(cc2n1C)C(F)(F)F

BDBM544879

Cc1c(CCOc2ccc(Cl)cc2-c2ccnc3c(csc23)C(O)=O)c(=O)c2c(cc(cc2n1CCF)C(F)(F)F)C#N

BDBM544880

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(C)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544881

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)c(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544882

CN(C)CCc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544883

CN1CCN(Cc2c(F)cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)CC1

BDBM544884

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(F)c(CN4CCOCC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544885

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(F)c(C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544886

COc1c(CN(C)C)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544887

CC(C)Oc1c(CN(C)C)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544888

CC(C)Oc1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544889

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(ncc(C#N)c3c2=O)C(F)F)c2scc(C(O)=O)c2n1

BDBM544890

CN1CCC(=CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O |c:4|

BDBM544891

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cccc(c3)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM544892

Cc1cccc(n1)-c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)c2=O

BDBM544893

Cc1nc2cc(c(CC3CN(CC(F)F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544894

Cc1nc2cc(c(N3CCN(CC(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)C(F)(F)F

BDBM544895

CC(=O)N1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cccc(c3)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM544896

Cc1nc2cc(c(N3CCN(CC3)c3ccccn3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)C(F)(F)F

BDBM544897

Cc1nc2cc(c(N3CCN(CC3)c3cccnc3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)C(F)(F)F

BDBM544898

Cc1nc2cnc(C3CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544899

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CC4)c(C#N)c3c2=O)c2scc(C(=O)NS(C)(=O)=O)c2n1

BDBM544900

Cc1nc2cc(c(-c3ccncc3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)C(F)(F)F

BDBM544901

Cc1nc2cc(c(N3CCN(CC3)c3ccncc3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)C(F)(F)F

BDBM544902

Cc1nc2cc(c(-c3cccnc3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)C(F)(F)F

BDBM544903

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cnc(C)c(C)c4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544904

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(Cc4ccccn4)nc3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544905

CCCCc1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM544906

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(-c4cc(F)cnc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1 |(10,1.93,;8.67,1.15,;7.34,1.93,;6,1.15,;4.67,1.93,;4.67,3.47,;3.33,4.23,;3.33,5.78,;2,3.47,;2,1.93,;3.33,1.15,;3.33,-.38,;2,-1.15,;2,-2.69,;.67,-3.47,;.67,-5,;2,-5.78,;-.67,-5.78,;-2,-5,;-3.33,-5.78,;-4.67,-5,;-6,-5.78,;-4.67,-3.47,;-6,-2.69,;-7.34,-3.47,;-8.67,-2.69,;-10,-3.47,;-8.67,-1.15,;-7.34,-.38,;-6,-1.15,;-4.67,-.39,;-3.33,-2.69,;-3.33,-1.15,;-3.33,.38,;-2,-3.47,;-.67,-2.69,;-.67,-1.15,;6,-.38,;4.86,-1.42,;5.48,-2.82,;7.02,-2.66,;8.05,-3.81,;9.55,-3.49,;7.57,-5.27,;7.34,-1.15,;8.67,-.38,)|

BDBM544907

Cc1cc(ccn1)-c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544908

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(-c4cncc(F)c4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544909

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(-c4cccnc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1 |(9.34,1.93,;8,1.15,;6.67,1.93,;5.33,1.15,;4,1.93,;4,3.47,;2.67,4.23,;2.67,5.78,;1.33,3.47,;1.33,1.93,;2.67,1.15,;2.67,-.38,;1.33,-1.15,;1.33,-2.69,;,-3.47,;,-5,;1.33,-5.78,;-1.33,-5.78,;-2.67,-5,;-4,-5.78,;-5.33,-5,;-6.67,-5.78,;-5.33,-3.47,;-6.67,-2.69,;-8,-3.47,;-9.34,-2.69,;-9.34,-1.15,;-8,-.38,;-6.67,-1.15,;-5.33,-.38,;-4,-2.69,;-4,-1.15,;-4,.38,;-2.67,-3.47,;-1.33,-2.69,;-1.33,-1.15,;5.33,-.38,;4.19,-1.42,;4.82,-2.82,;6.35,-2.66,;7.38,-3.81,;8.88,-3.49,;6.9,-5.27,;6.67,-1.15,;8,-.38,)|

BDBM544910

Cc1cc(cc(C)n1)-c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544911

CN(C)c1ccc(cn1)-c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544912

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(=O)NCC(O)=O)c2n1

BDBM544913

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(Cc4cccnc4)c(Cl)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544914

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(CC4CCOCC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544915

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc2c(csc12)C(O)=O)C(F)(F)F

BDBM544917

COc1ccc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM544918

COc1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544919

COc1cc(C#N)c2c(c1)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM544920

Cc1nc2ccc(OC(F)(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544921

Cc1nc2c(F)cc(Cl)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544922

CN(C)Cc1cc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM544923

Cc1cc(-c2cc(Cl)ccc2OCCc2c(C)n(C)c3cc(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544924

Cc1cc(cc(n1)C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM544925

Cc1cc(cc(CC(O)=O)n1)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM544926

CNC(=O)c1cc(C#N)c2c(c1)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM544927

CN(C)C(=O)c1cc(C#N)c2c(c1)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM544928

CC(=O)c1cnn2c(cc(C)nc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM544929

Cc1nc2cc(c(C)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544930

Cc1nc2c(C)c(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544931

CN1CCN(Cc2c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(C(O)=O)c(C)sc45)c(=O)c3c2C#N)C(F)(F)F)CC1

BDBM544932

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544933

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544934

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(c(C#N)c3c2=O)C(C)(C)C)c2scc(C(O)=O)c2n1

BDBM544935

Cc1sc2c(cc(C)nc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(-c3ccccn3)c(C#N)c2c1=O)C(F)(F)F

BDBM544936

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CCCC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544937

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CCCCC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544938

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CC4CNC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544939

CN1CC(Cc2c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)C(F)(F)F)C1

BDBM544940

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(cc3c2=O)-c2ccccn2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544941

CN1CCN(CC1)c1cc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM544942

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CCN(CC(F)F)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544943

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(C4=CCOCC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |t:23|

BDBM544944

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CCN(CCF)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544945

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(C4CCOCC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544946

CC(C)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544947

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ncc(F)cc4F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(10,2.7,;8.67,1.92,;7.34,2.69,;6,1.92,;4.67,2.69,;4.67,4.23,;3.33,5,;3.33,6.54,;2,4.23,;2,2.69,;3.33,1.92,;3.33,.38,;2,-.39,;2,-1.93,;.67,-2.7,;.67,-4.24,;2,-5.01,;-.67,-5.01,;-2,-4.24,;-3.33,-5.01,;-4.67,-4.24,;-4.67,-2.7,;-6,-1.93,;-7.34,-2.7,;-8.67,-1.93,;-8.67,-.39,;-10,.38,;-7.34,.39,;-6,-.39,;-4.67,.38,;-3.33,-1.92,;-3.33,-.38,;-3.33,1.16,;-2,-2.7,;-.67,-1.93,;-.67,-.39,;-6,-5,;-7.34,-4.23,;-6,-6.54,;-7.34,-5.77,;6,.38,;4.86,-.65,;5.48,-2.05,;7.02,-1.89,;8.05,-3.04,;9.55,-2.72,;7.57,-4.5,;7.34,-.39,;8.67,.38,)|

BDBM544948

Cc1ccc(F)c(n1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-10,-2.7,;-8.67,-1.93,;-8.67,-.39,;-7.34,.39,;-6,-.39,;-4.67,.38,;-6,-1.93,;-7.34,-2.7,;-4.67,-2.7,;-4.67,-4.24,;-3.33,-5.01,;-2,-4.24,;-.67,-5.01,;.67,-4.24,;2,-5.01,;.67,-2.7,;2,-1.93,;2,-.39,;3.33,.38,;3.33,1.92,;2,2.69,;2,4.23,;3.33,5,;3.33,6.54,;4.67,4.23,;4.67,2.69,;6,1.92,;7.34,2.69,;8.67,1.92,;10,2.7,;8.67,.38,;7.34,-.39,;7.02,-1.89,;5.48,-2.05,;4.86,-.65,;6,.38,;8.05,-3.04,;9.55,-2.72,;7.57,-4.5,;-.67,-1.93,;-.67,-.39,;-2,-2.7,;-3.33,-1.92,;-3.33,-.38,;-3.33,1.16,;-6,-5,;-7.34,-4.23,;-6,-6.54,;-7.34,-5.77,)|

BDBM544949

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CCC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544950

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2ccncc2C)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544951

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cnc(C)nc4C)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(10,2.7,;8.67,1.92,;7.34,2.69,;6,1.92,;4.67,2.69,;4.67,4.23,;3.33,5,;3.33,6.54,;2,4.23,;2,2.69,;3.33,1.92,;3.33,.38,;2,-.39,;2,-1.93,;.67,-2.7,;.67,-4.24,;2,-5.01,;-.67,-5.01,;-2,-4.24,;-3.33,-5.01,;-4.67,-4.24,;-4.67,-2.7,;-6,-1.93,;-7.34,-2.7,;-8.67,-1.93,;-8.67,-.39,;-10,.38,;-7.34,.39,;-6,-.39,;-4.67,.38,;-3.33,-1.92,;-3.33,-.38,;-3.33,1.16,;-2,-2.7,;-.67,-1.93,;-.67,-.39,;-6,-5,;-7.34,-4.23,;-6,-6.54,;-7.34,-5.77,;6,.38,;4.86,-.65,;5.48,-2.05,;7.02,-1.89,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;7.34,-.39,;8.67,.38,)|

BDBM544952

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(C(F)F)c(-c4cc(F)cnc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1 |(10,2.7,;8.67,1.93,;7.34,2.69,;6,1.93,;4.67,2.69,;4.67,4.23,;3.33,5,;3.33,6.54,;2,4.23,;2,2.69,;3.33,1.93,;3.33,.38,;2,-.38,;2,-1.93,;.67,-2.69,;.67,-4.23,;2,-5,;-.67,-5,;-2,-4.23,;-3.33,-5,;-4.67,-4.23,;-6,-5,;-7.34,-4.23,;-6,-6.54,;-4.67,-2.69,;-6,-1.92,;-7.34,-2.69,;-8.67,-1.92,;-10,-2.69,;-8.67,-.38,;-7.34,.39,;-6,-.38,;-4.67,.38,;-3.33,-1.93,;-3.33,-.38,;-3.33,1.15,;-2,-2.69,;-.67,-1.93,;-.67,-.38,;6,.38,;4.86,-.65,;5.48,-2.05,;7.02,-1.89,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;7.34,-.38,;8.67,.38,)|

BDBM544953

CN(C)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)F

BDBM544954

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(C(F)F)c(O)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544955

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(C(F)F)c(-c4cccnc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1 |(9.34,2.7,;8,1.92,;6.67,2.69,;5.33,1.92,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.92,;2.67,.38,;1.33,-.39,;1.33,-1.93,;,-2.7,;,-4.24,;1.33,-5.01,;-1.33,-5.01,;-2.67,-4.24,;-4,-5.01,;-5.33,-4.24,;-6.67,-5.01,;-8,-4.24,;-6.67,-6.54,;-5.33,-2.7,;-6.67,-1.92,;-8,-2.7,;-9.34,-1.92,;-9.34,-.38,;-8,.39,;-6.67,-.38,;-5.33,.38,;-4,-1.93,;-4,-.39,;-4,1.15,;-2.67,-2.7,;-1.33,-1.93,;-1.33,-.39,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.39,;8,.38,)|

BDBM544956

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4cc(F)cnc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544957

Cc1cc(cnn1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM544958

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(C(O)=O)c(sc12)C(C)(C)C)C(F)(F)F

BDBM544959

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cc(Cl)nc2c(csc12)C(O)=O)C(F)(F)F

BDBM544960

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cc(nc2c(csc12)C(O)=O)C(N)=O)C(F)(F)F

BDBM544961

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cc(nc2c(csc12)C(O)=O)C#N)C(F)(F)F

BDBM544962

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(cc(C#N)c3c2=O)C(F)(F)F)c2csc(C(O)=O)c2n1

BDBM544963

CN1CCN(CC1)c1nc(C)c2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544964

CN(C)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1OC(F)F

BDBM544965

CN1CCN(CC1)c1nc(C)c2nc(C)n(CC#Cc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544966

CN(C)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c(C#N)c1OC(F)F

BDBM544967

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cc(CN)nc2c(csc12)C(O)=O)C(F)(F)F

BDBM544968

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccnnc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544969

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1cnc(Cl)nc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM544970

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1cnc(nc1-c1ccnc2c(csc12)C(O)=O)C#N)C(F)(F)F

BDBM544971

Cc1nc2cc(OC(F)(F)F)cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM544972

CN(C)CCOc1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544973

CN(C)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1OC(F)F

BDBM544974

Cc1nc(C)c2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544975

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(C)nc3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544976

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2cccnc2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544977

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2ccccn2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544978

Cc1cc(ccn1)-c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM544979

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2ccncc2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544980

Cc1cc(cc(C)n1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM544981

CCc1ncccc1-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-5.33,1.93,;-5.33,.38,;-6.67,-.38,;-8,.38,;-9.34,-.38,;-9.34,-1.93,;-8,-2.69,;-6.67,-1.93,;-5.33,-2.69,;-5.33,-4.23,;-4,-5,;-2.67,-4.23,;-1.33,-5,;,-4.23,;1.33,-5,;,-2.69,;1.33,-1.93,;1.33,-.38,;2.67,.38,;2.67,1.93,;1.33,2.69,;1.33,4.23,;2.67,5,;2.67,6.54,;4,4.23,;4,2.69,;5.33,1.93,;6.67,2.69,;8,1.93,;9.34,2.69,;8,.38,;6.67,-.38,;6.35,-1.89,;4.82,-2.05,;4.19,-.65,;5.33,.38,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;-1.33,-1.93,;-1.33,-.38,;-2.67,-2.69,;-4,-1.93,;-4,-.38,;-4,1.15,;-6.67,-5,;-8,-4.23,;-6.67,-6.54,;-8,-5.78,)|

BDBM544982

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2ccccc2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544983

CCc1cc(ccn1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM544984

Cc1cc(c(C)cn1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-10,-2.69,;-8.67,-1.93,;-7.34,-2.69,;-6,-1.93,;-6,-.38,;-4.67,.38,;-7.34,.38,;-8.67,-.38,;-4.67,-2.69,;-4.67,-4.23,;-3.33,-5,;-2,-4.23,;-.67,-5,;.67,-4.23,;2,-5,;.67,-2.69,;2,-1.93,;2,-.38,;3.33,.38,;3.33,1.93,;2,2.69,;2,4.23,;3.33,5,;3.33,6.54,;4.67,4.23,;4.67,2.69,;6,1.93,;7.34,2.69,;8.67,1.93,;10,2.69,;8.67,.38,;7.34,-.38,;7.02,-1.89,;5.48,-2.05,;4.86,-.65,;6,.38,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;-.67,-1.93,;-.67,-.38,;-2,-2.69,;-3.33,-1.93,;-3.33,-.38,;-3.33,1.15,;-6,-5,;-7.34,-4.23,;-6,-6.54,;-7.34,-5.78,)|

BDBM544985

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cc(F)cnc4F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(10,2.69,;8.67,1.93,;7.34,2.69,;6,1.93,;4.67,2.69,;4.67,4.23,;3.33,5,;3.33,6.54,;2,4.23,;2,2.69,;3.33,1.93,;3.33,.38,;2,-.38,;2,-1.93,;.67,-2.69,;.67,-4.23,;2,-5,;-.67,-5,;-2,-4.23,;-3.33,-5,;-4.67,-4.23,;-4.67,-2.69,;-6,-1.93,;-7.34,-2.69,;-8.67,-1.93,;-10,-2.69,;-8.67,-.38,;-7.34,.38,;-6,-.38,;-4.67,.38,;-3.33,-1.93,;-3.33,-.38,;-3.33,1.15,;-2,-2.69,;-.67,-1.93,;-.67,-.38,;-6,-5,;-7.34,-4.23,;-6,-6.54,;-7.34,-5.78,;6,.38,;4.86,-.65,;5.48,-2.05,;7.02,-1.89,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;7.34,-.38,;8.67,.38,)|

BDBM544986

Cc1cc(c(F)cn1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-10,-2.7,;-8.67,-1.93,;-7.34,-2.7,;-6,-1.93,;-6,-.39,;-4.67,.38,;-7.34,.38,;-8.67,-.39,;-4.67,-2.7,;-4.67,-4.24,;-3.33,-5.01,;-2,-4.24,;-.67,-5.01,;.67,-4.24,;2,-5.01,;.67,-2.7,;2,-1.93,;2,-.39,;3.33,.38,;3.33,1.92,;2,2.69,;2,4.23,;3.33,5,;3.33,6.54,;4.67,4.23,;4.67,2.69,;6,1.92,;7.34,2.69,;8.67,1.92,;10,2.69,;8.67,.38,;7.34,-.39,;7.02,-1.89,;5.48,-2.05,;4.86,-.65,;6,.38,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;-.67,-1.93,;-.67,-.39,;-2,-2.7,;-3.33,-1.92,;-3.33,-.38,;-3.33,1.16,;-6,-5,;-7.34,-4.23,;-6,-6.54,;-7.34,-5.77,)|

BDBM544987

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccnc(C)c4F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(9.34,2.69,;8,1.92,;6.67,2.69,;5.33,1.92,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.92,;2.67,.38,;1.33,-.39,;1.33,-1.93,;,-2.7,;,-4.24,;1.33,-5.01,;-1.33,-5.01,;-2.67,-4.24,;-4,-5.01,;-5.33,-4.24,;-5.33,-2.7,;-6.67,-1.93,;-8,-2.7,;-9.34,-1.93,;-9.34,-.39,;-8,.38,;-8,1.92,;-6.67,-.39,;-5.33,.38,;-4,-1.92,;-4,-.38,;-4,1.16,;-2.67,-2.7,;-1.33,-1.93,;-1.33,-.39,;-6.67,-5,;-8,-4.23,;-6.67,-6.54,;-8,-5.77,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.39,;8,.38,)|

BDBM544988

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(Cc4ncccc4F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM544989

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4ccc(F)cc4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544990

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4cccc(F)c4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544991

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4ccccc4F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544992

Cc1ccc(cc1)-c1nc(C)c2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544993

Cc1cccc(c1)-c1nc(C)c2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM544994

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4ccccc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544995

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4ccc(Cl)cc4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544996

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4cccc(Cl)c4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544997

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4ccccc4Cl)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM544998

CN1CCN(Cc2c(cc(C#N)c3c2nc(C)n(CCOc2ccc(Cl)cc2-c2cc(C)nc4c(csc24)C(O)=O)c3=O)C(F)(F)F)CC1

BDBM544999

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cc(CO)nc2c(csc12)C(O)=O)C(F)(F)F

BDBM545000

CN1CCN(Cc2c(C#N)c3c(cc2C(F)(F)F)nc(C)n(CCOc2ccc(Cl)cc2-c2cc(C)nc4c(csc24)C(O)=O)c3=O)CC1

BDBM545001

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CN4CCOCC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545002

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C1=C(O)CCC1=O)C(F)(F)F |c:38|

BDBM545003

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(F)cc(C(F)F)c(C#N)c3c2=O)c2scc(c2n1)S(O)(=O)=O

BDBM545004

COCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CN4CCN(C)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545005

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(F)cc(C(F)F)c(C#N)c3c2=O)c2cccc(C(O)=O)c2n1

BDBM545006

CC(C)c1ncc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545007

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545008

Cc1nc2cc(Cl)c(c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)S(C)(=O)=O

BDBM545009

Cc1nc2cc(c(CC3CN(CC(F)(F)F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545010

Cc1cnc2c(csc2c1-c1cc(Cl)ccc1OCCn1c(C)nc2cc(cc(C#N)c2c1=O)C(F)(F)F)C(O)=O |(6.23,4.23,;6.23,2.69,;7.56,1.92,;7.56,.38,;6.23,-.39,;5.91,-1.89,;4.38,-2.05,;3.75,-.65,;4.89,.38,;4.89,1.92,;3.56,2.69,;3.56,4.23,;2.23,5,;2.23,6.54,;.89,4.23,;.89,2.69,;2.23,1.92,;2.23,.38,;.89,-.39,;.89,-1.93,;-.44,-2.7,;-.44,-4.24,;.89,-5.01,;-1.78,-5.01,;-3.11,-4.24,;-4.44,-5.01,;-5.78,-4.24,;-5.78,-2.7,;-4.44,-1.92,;-4.44,-.38,;-4.44,1.16,;-3.11,-2.7,;-1.78,-1.93,;-1.78,-.39,;-7.11,-5,;-8.44,-4.23,;-7.11,-6.54,;-8.44,-5.77,;6.94,-3.04,;6.46,-4.5,;8.44,-2.72,)|

BDBM545011

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2C(CCc12)C(O)=O)C(F)(F)F

BDBM545012

Cc1nc2c(Cl)cc(C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545013

Cc1nc2c(F)c(Cl)c(C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545014

Cc1nc2cc(cc(Cl)n2c(=O)c1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545016

Cc1nc2cc(c(CN3CCOCC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545017

CN1CCN(Cc2c(C#N)c3c(cc2C(F)(F)F)nc(C)n(CCOc2ccc(Cl)cc2-c2ccnc4c(csc24)C(O)=O)c3=O)CC1

BDBM545018

CN(C)Cc1c(cc2nc(C)n(CCOc3cc(F)c(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545019

Cc1nc2c(F)cc(C(F)F)c(C#N)c2c(=O)n1CCOc1cc(F)c(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545020

Cc1nc2cc(c(Cl)c(C#N)c2c(=O)n1CCOc1cc(F)c(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545021

Cc1nc2cc(F)c(F)c(C#N)c2c(=O)n1CCOc1cc(F)c(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545022

CN(C)CCc1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545023

CN(C)Cc1cc(F)c2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545024

CN(C)Cc1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545025

CN(C)Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C#N

BDBM545026

CN(C)Cc1c(cc2cc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C#N

BDBM545027

CN(C)Cc1cc(C#N)c2c(c1)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545028

CN(C)CCc1cc(C#N)c2c(c1)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545029

CN(C)CC(F)(F)c1cc(C#N)c2c(c1)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545030

CN(C)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1C(F)F

BDBM545031

CN(C)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1Cl

BDBM545032

CN(C)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1F

BDBM545033

CN(C)Cc1c(F)c2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1C(F)F

BDBM545034

Cc1nc2cc(c(Cl)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O)C(F)(F)F

BDBM545035

Cc1nc2cc(Cl)c(C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O

BDBM545036

CONC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(Cl)c(C#N)c2c1=O)C(F)(F)F

BDBM545037

Cc1nc2cc(c(CN3CCC(F)(F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545038

Cc1nc2cc(c(CN3[C@H]4CC[C@@H]3COC4)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F |r,THB:7:8:13.14.15:10.11|

BDBM545039

CN1CCCC(Cc2c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4ccnc5c(C(O)=O)c(C)sc45)c(=O)c3c2C#N)C(F)(F)F)C1

BDBM545040

CN(CC(F)F)Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545041

Cc1nc2cc(c(CN3CCCC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545042

CCN(CC)Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545043

Cc1nc2cc(c(CN3CCCCC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545044

CN(C)CC(F)(F)c1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545045

CN(C)Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)F

BDBM545046

CN(C)Cc1c(OC(F)F)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545047

CN(C)Cc1c(OC(F)(F)F)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545048

COCc1cc(F)c2cc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545049

CSCc1cc(F)c2cc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545050

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1C1CCNC(C1)C(O)=O)C(F)(F)F

BDBM545051

Cc1cc2cc(OC(F)F)c(F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545052

Cc1nc2cc(OC(F)F)c(Cl)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545053

Cc1nc2cc(OC(F)F)c(C#N)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545054

Cc1nc2cc(OC(F)F)c(C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545055

Cc1nc2cc(OC(F)F)c(c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545056

Cc1nc2cc(OC(F)F)c(OC(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545057

Cc1nc2cc(OC(F)(F)F)c(Cl)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545058

Cc1nc2cc(OC(F)(F)F)c(C#N)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545059

Cc1nc2cc(OC(F)(F)F)c(C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545060

Cc1nc2cc(F)c(OC(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545061

Cc1nc2cc(Cl)c(OC(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545062

Cc1nc2cc(C#N)c(OC(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545063

Cc1nc2cc(C(F)F)c(OC(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545064

Cc1nc2cc(c(OC(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545065

Cc1nc2cc(Cl)c(OC(F)(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545066

Cc1nc2cc(C(F)F)c(OC(F)(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545067

CN(C)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1OC(F)(F)F

BDBM545068

CN(C)Cc1c(cc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545069

Cc1nc2cc(c(Cl)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545070

Cc1sc2c(ccnc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(Cl)c(C#N)c2c1=O)C(F)(F)F

BDBM545071

CN(C)Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545072

Cc1nc2c(F)cc(C(F)F)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545073

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(Cl)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545074

CN(C)Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545075

Cc1cc(-c2cc(Cl)ccc2C#CCn2c(C)nc3cc(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545076

Cc1cc(-c2cc(Cl)ccc2C#CCn2c(C)nc3cc(c(Cl)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545077

CN(C)Cc1c(cc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545078

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cc(nc2c(csc12)C(O)=O)C(F)F)C(F)(F)F

BDBM545079

CN(C)Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccc(C)c4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545080

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(=O)NS(C)(=O)=O)c2n1

BDBM545081

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(F)cc(C(F)F)c(C#N)c3c2=O)c2scc(C(=O)NS(C)(=O)=O)c2n1

BDBM545082

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(F)c(F)c(C#N)c3c2=O)c2scc(C(=O)NS(C)(=O)=O)c2n1

BDBM545083

CN(C)Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545084

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O)C(F)(F)F

BDBM545085

CC(=O)NS(=O)(=O)c1csc2c(cc(C)nc12)-c1cc(Cl)ccc1OCCn1c(C)nc2c(F)cc(C(F)F)c(C#N)c2c1=O

BDBM545086

Cc1cc(-c2cc(Cl)c(F)cc2OCCn2c(C)nc3cc(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545087

Cc1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545088

Cc1cc(C#N)c2c(c1)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545089

Cc1ccc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545090

CN(C)CCc1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(OC(F)F)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545091

CN(C)CCc1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccc(C)c4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545092

CN(C)CCc1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccc(C(F)F)c4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545093

CN(C)CCc1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccc(c4c(csc34)C(O)=O)C(F)(F)F)c(=O)c2c1C#N

BDBM545094

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(OC(F)F)cc(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545095

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(OC(F)F)cc(C#N)c3c2=O)c2scc(C(=O)NS(C)(=O)=O)c2n1

BDBM545096

Cc1cc(-c2cc(Cl)ccc2C#CCn2c(C)nc3cc(OC(F)F)cc(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545097

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(Cl)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545098

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3ccc(OC(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545099

CN(C)CCc1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545100

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(OC(F)F)c(F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545101

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(C(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545102

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(F)cc(C(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545103

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(F)cc(Cl)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545104

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(F)c(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545105

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cn(C)c(=O)c2c(csc12)C(O)=O)C(F)(F)F

BDBM545106

CCc1sc2c(ccnc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM545107

CN(C)CCc1c(OC(F)F)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545108

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(F)cc(C(F)F)c(C#N)c3c2=O)c2scc(C(=O)NS(=O)(=O)C(F)(F)F)c2n1

BDBM545109

CN(C)C(=O)NC(=O)c1csc2c(cc(C)nc12)-c1cc(Cl)ccc1OCCn1c(C)nc2c(F)cc(C(F)F)c(C#N)c2c1=O

BDBM545110

CC1=Nc2cc(cc(C#N)c2C(=C)N1CCOc1ccc(Cl)cc1-c1cc(CCO)nc2c(csc12)C(O)=O)C(F)(F)F |t:1|

BDBM545111

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(cc3c2=O)C#N)c2scc(C(O)=O)c2n1

BDBM545112

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cncc(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545113

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(cc3c2=O)C#N)c2scc(C(=O)NS(C)(=O)=O)c2n1

BDBM545114

Cc1cc(-c2cc(Cl)ccc2C#CCn2c(C)nc3cnc(cc3c2=O)C#N)c2scc(C(O)=O)c2n1

BDBM545115

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cncc(C#N)c3c2=O)c2scc(C(=O)NS(C)(=O)=O)c2n1

BDBM545116

Cc1cc(-c2cc(Cl)ccc2C#CCn2c(C)nc3cncc(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545117

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(OC(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545118

CN1CCN(C2CC12)c1nc(C)c2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545119

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(OC(F)F)ncc(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545120

CN(C)CCCc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1Cl

BDBM545121

CN(C)CCc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1OC(F)F

BDBM545122

CN(C)CCc1cc(F)c2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545123

CN(C)CCc1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545124

CN(C)CCc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545125

CN(C)C1Cc2cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c(C#N)c2C1

BDBM545126

CN(C)C1CCc2cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c(C#N)c12

BDBM545127

CN(C)C1CCc2c1cc1nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c1c2C#N

BDBM545129

CN1CCN(Cc2c(cc3nc(C)n(CC#Cc4ccc(Cl)cc4-c4ccnc5c(csc45)C(O)=O)c(=O)c3c2C#N)C(F)(F)F)CC1

BDBM545130

CN1CCN(Cc2c(cc3nc(C)n(CC#Cc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)C(F)(F)F)CC1

BDBM545131

Cc1nc2cc(c(CN3CCOCC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545132

CN(Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1OC(F)F)C(C)(C)C

BDBM545133

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(CNC(C)(C)C)c(OC(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545134

CN(C)Cc1c(C)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545135

CN(C)Cc1c(F)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545136

CN(C)Cc1c(cc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)F

BDBM545137

CN(C)Cc1cc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1C(F)(F)F

BDBM545138

Cc1nc2cncc(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545139

Cc1nc2cnc(cc2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C#N

BDBM545140

CN(C)Cc1cc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1OC(F)F

BDBM545141

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(C(F)F)c(C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545142

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(C)c(C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545143

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccncc4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545144

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cccnc4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545145

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccccn4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545146

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(c(C#N)c3c2=O)-n2ccnc2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545147

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(c(C#N)c3c2=O)-n2cccn2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545148

CN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545149

CN(C)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1C(F)(F)F

BDBM545150

CN(C)Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545151

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CN4CCN(C)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545152

COc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CN4CCN(C)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545153

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(CN(C)C)c(OC(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545154

Cc1nc2cc(c(N3CCN(CC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545155

CN(C)Cc1c(cc2ncn(CCOc3ccc(Cl)cc3-c3ccnc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545156

C[C@H]1CN(Cc2c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)C(F)(F)F)C[C@@H](C)O1 |r|

BDBM545157

CN1CCN(Cc2c(cc3nc(C)n(CC#Cc4ccc(Cl)cc4-c4ccnc5c(C(O)=O)c(C)sc45)c(=O)c3c2C#N)C(F)(F)F)CC1

BDBM545158

CN1CCN(Cc2c(C#N)c3c(cc2C(F)(F)F)nc(C)n(CCOc2ccc(Cl)cc2-c2cc(CCF)nc4c(csc24)C(O)=O)c3=O)CC1

BDBM545159

CN1CCN(Cc2c(C#N)c3c(cc2C(F)(F)F)nc(C)n(CCOc2ccc(Cl)cc2-c2cc(CF)nc4c(csc24)C(O)=O)c3=O)CC1

BDBM545160

CN1CCN(Cc2c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)C(F)F)CC1

BDBM545161

CN1CCN(Cc2ccc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)CC1

BDBM545162

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(F)cc(C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545163

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CN4CCNCC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545164

CN(C)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1C

BDBM545165

CN(Cc1cn(C)nn1)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1OC(F)F

BDBM545166

CN1CC(C1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545167

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(-c4cccnc4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545168

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(cc(C#N)c3c2=O)-c2cccnc2)c2scc(C(O)=O)c2n1

BDBM545169

Cc1nc2cc(c(N3CCN(CCF)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545170

CN1CCN(C2CC12)c1nc(C)c2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545171

OC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c2ccccc2c2cccc(C#N)c2c1=O

BDBM545172

OC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c2cnncc2c2ccccc2c1=O

BDBM545173

Cc1nc2c3cnncc3ccc2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545174

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cncc(c1)-c1nn[nH]n1)C(F)(F)F

BDBM545175

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(cnn12)C(O)=O)C(F)(F)F

BDBM545176

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc(c1)-c1nnn[nH]1)C(F)(F)F

BDBM545177

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(O)csc12)C(F)(F)F

BDBM545178

COC(=O)c1sc2cc(cnc2c1O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM545179

Cc1c(CC#Cc2ccc(Cl)cc2-c2ccnc3c(csc23)C(O)=O)c(=O)c2c(cc(cc2n1C)C(F)(F)F)C#N

BDBM545180

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(C(O)=O)c(sc12)C(F)(F)F)C(F)(F)F

BDBM545181

CC(C)c1sc2c(ccnc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM545182

Cc1sc2c(cc(C)nc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM545183

Cc1c(CC#Cc2ccc(Cl)cc2-c2ccnc3c(csc23)C(O)=O)c(=O)c2c(C#N)c(Cl)c(cc2n1C)C(F)(F)F

BDBM545184

CN(C)Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545185

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c4cnncc4ccc3c2=O)c2scc(C(O)=O)c2n1

BDBM545186

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cc(nc2c(csc12)C(O)=O)C1CC1)C(F)(F)F

BDBM545187

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)ncc(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545188

Cc1nc2c(C)ncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545189

Cc1cccc(n1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545190

CN1CCN(CC1)c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545191

CN1CCN(CC1)c1cc(c2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2n1)C(F)(F)F

BDBM545192

CN1CCN(CC1)c1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2n1

BDBM545193

CN(C)c1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2n1

BDBM545194

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(cc(Cl)nc3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545195

Cc1cccc(n1)-c1c(Cl)cc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545196

CN1CCN(CC1)c1nc2c(cc1C(F)(F)F)nc(C)n(CC#Cc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545197

Cc1sc2c(cc(C)nc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(Cl)c(-c3cccc(C)n3)c(C#N)c2c1=O

BDBM545198

Cc1cc(F)cc(n1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545199

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(C)nc(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545200

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccnc(C)c4C)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(9.34,2.69,;8,1.93,;6.67,2.7,;5.33,1.93,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.93,;2.67,.38,;1.33,-.38,;1.33,-1.93,;,-2.69,;,-4.23,;1.33,-5,;-1.33,-5,;-2.67,-4.23,;-4,-5,;-5.33,-4.23,;-5.33,-2.69,;-6.67,-1.92,;-8,-2.69,;-9.34,-1.92,;-9.34,-.38,;-8,.39,;-8,1.93,;-6.67,-.38,;-5.33,.38,;-4,-1.93,;-4,-.38,;-4,1.15,;-2.67,-2.69,;-1.33,-1.93,;-1.33,-.38,;-6.67,-5,;-8,-4.23,;-6.67,-6.54,;-8,-5.78,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.38,;8,.38,)|

BDBM545201

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CC(F)(F)C4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545202

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CC(F)(F)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545203

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CC(C4)C(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545204

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CCC(F)(F)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545205

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CC(C)(C)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545206

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545207

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)cc(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545208

CNc1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545209

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(O)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545210

CN(C)c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545211

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CCCC4=O)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545212

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CC(O)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545213

Cc1ncsc1-c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545214

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(Nc4cccnc4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545215

COC1CN(C1)c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545216

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CC(C4)S(C)(=O)=O)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545217

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CC(C)(CO)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545218

CSC1CN(C1)c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545219

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4ccsc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545220

Cc1ncc(F)cc1-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4ccsc34)c(=O)c2c1C#N)C(F)(F)F |(-4,.38,;-5.33,-.38,;-6.67,.39,;-8,-.38,;-8,-1.92,;-9.34,-2.69,;-6.67,-2.69,;-5.33,-1.92,;-4,-2.69,;-4,-4.23,;-2.67,-5,;-1.33,-4.23,;,-5,;1.33,-4.23,;2.67,-5,;1.33,-2.69,;2.67,-1.93,;2.67,-.38,;4,.38,;4,1.93,;2.67,2.69,;2.67,4.23,;4,5,;4,6.54,;5.33,4.23,;5.33,2.69,;6.67,1.93,;8,2.7,;9.34,1.93,;9.34,.38,;8,-.38,;7.68,-1.89,;6.15,-2.05,;5.52,-.65,;6.67,.38,;,-1.93,;,-.38,;-1.33,-2.69,;-2.67,-1.93,;-2.67,-.38,;-2.67,1.15,;-5.33,-5,;-6.67,-4.23,;-5.33,-6.54,;-6.67,-5.78,)|

BDBM545221

CN1CCN(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545222

CN1CCCC1c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545223

CN(C)CCCc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545224

CC(N(C)C)c1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1OC(F)F

BDBM545225

CC(N(C)C)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545226

CN1Cc2cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c(C#N)c2C1

BDBM545227

CN1CCC(Cc2c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)C(F)(F)F)CC1

BDBM545228

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CC4CCNCC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545229

CN(C)Cc1c(cc2ncn(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545230

CN1CCN(Cc2c(C)cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)CC1

BDBM545231

CN1CCN(Cc2c(C#N)c3c(cc2C(F)(F)F)nc(C)n(CCOc2ccc(Cl)cc2-c2ccc(C)c4c(csc24)C(O)=O)c3=O)CC1

BDBM545232

Cc1nc2cc(Cl)c3n(C)ncc3c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545233

COc1ccc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)ncc(C#N)c3c2=O)c2scc(C(O)=O)c12

BDBM545234

Cc1ccc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)ncc(C#N)c3c2=O)c2scc(C(O)=O)c12

BDBM545235

Cc1nc2c(C)ncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccc(Cl)c2c(csc12)C(O)=O

BDBM545236

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(CF)c(C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545237

CN(C)c1ncc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccc(C)c3c(csc13)C(O)=O)c2=O

BDBM545238

COc1ncc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccc(C)c3c(csc13)C(O)=O)c2=O

BDBM545239

COCc1ncc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccc(C)c3c(csc13)C(O)=O)c2=O

BDBM545240

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(C(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545241

Cc1ccc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(nc(c(C)c3c2=O)-c2cccnc2)C#N)c2scc(C(O)=O)c12

BDBM545242

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545243

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)ncc(C#N)c3c2=O)c2scc(C(=O)NS(C)(=O)=O)c2n1

BDBM545244

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)ncc(C#N)c3c2=O)c2scc(c2n1)C(O)(O)C(F)(F)F

BDBM545245

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)ncc(C#N)c3c2=O)c2scc(C(O)C(F)(F)F)c2n1

BDBM545247

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cccnc4C)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(9.34,2.69,;8,1.93,;6.67,2.69,;5.33,1.93,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.93,;2.67,.38,;1.33,-.38,;1.33,-1.93,;,-2.69,;,-4.23,;1.33,-5,;-1.33,-5,;-2.67,-4.23,;-4,-5,;-5.33,-4.23,;-5.33,-2.69,;-6.67,-1.93,;-8,-2.69,;-9.34,-1.93,;-9.34,-.38,;-8,.38,;-6.67,-.38,;-5.33,.39,;-4,-1.93,;-4,-.38,;-4,1.15,;-2.67,-2.69,;-1.33,-1.93,;-1.33,-.38,;-6.67,-5,;-8,-4.23,;-6.67,-6.54,;-8,-5.78,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.38,;8,.38,)|

BDBM545248

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cnccc4C)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(9.34,2.69,;8,1.93,;6.67,2.69,;5.33,1.93,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.93,;2.67,.38,;1.33,-.38,;1.33,-1.93,;,-2.69,;,-4.23,;1.33,-5,;-1.33,-5,;-2.67,-4.23,;-4,-5,;-5.33,-4.23,;-5.33,-2.69,;-6.67,-1.93,;-8,-2.69,;-9.34,-1.93,;-9.34,-.38,;-8,.38,;-6.67,-.38,;-5.33,.39,;-4,-1.93,;-4,-.38,;-4,1.15,;-2.67,-2.69,;-1.33,-1.93,;-1.33,-.38,;-6.67,-5,;-8,-4.23,;-6.67,-6.54,;-8,-5.78,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.38,;8,.38,)|

BDBM545249

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4ccccc4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545250

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CN4CCN(CC4)C(C)(C)C)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545251

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CN4CCN(CC(F)F)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545252

CN1C2CCC1CN(Cc1c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c1C#N)C(F)(F)F)C2

BDBM545253

CN1CCN(CC1)c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N

BDBM545254

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(C4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545255

Cc1ccc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(nc(c(C)c3c2=O)-c2ccccn2)C#N)c2scc(C(O)=O)c12

BDBM545256

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(nc3c2=O)C2CC2)c2scc(C(O)=O)c2n1

BDBM545257

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nccc3c2=O)c2scc(C(O)=O)c2n1

BDBM545258

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(C)cc3c2=O)c2scc(C(O)=O)c2n1

BDBM545259

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccccn4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545260

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc4CCCc4c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545261

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)ncc(C#N)c3c2=O)c2scc(c2n1)C(O)(C(F)(F)F)C(F)(F)F

BDBM545262

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(nc3c2=O)N2CCC2)c2scc(C(O)=O)c2n1

BDBM545263

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ncccc4F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(9.34,2.69,;8,1.93,;6.67,2.69,;5.33,1.93,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.93,;2.67,.38,;1.33,-.38,;1.33,-1.93,;,-2.69,;,-4.23,;1.33,-5,;-1.33,-5,;-2.67,-4.23,;-4,-5,;-5.33,-4.23,;-5.33,-2.69,;-6.67,-1.93,;-8,-2.69,;-9.34,-1.93,;-9.34,-.38,;-8,.38,;-6.67,-.38,;-5.33,.38,;-4,-1.93,;-4,-.38,;-4,1.15,;-2.67,-2.69,;-1.33,-1.93,;-1.33,-.38,;-6.67,-5,;-8,-4.23,;-6.67,-6.54,;-8,-5.78,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.38,;8,.38,)|

BDBM545264

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CCC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545265

Cc1nc2cc(c(C)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cn(C)c(=O)c2c(csc12)C(O)=O)C(F)(F)F

BDBM545266

Cc1nc2cc(c(C)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1cn(C)c(=O)c2c(csc12)C(O)=O)C(F)(F)F

BDBM545267

CCCCn1cc(CN(C)Cc2cc3nc(C)n(CCOc4ccc(Cl)cc4-c4ccnc5c(csc45)C(O)=O)c(=O)c3c(C#N)c2OC(F)F)nn1

BDBM545268

Cc1nc2cnc(C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-n1cnc2c(cccc12)C(O)=O

BDBM545269

CSc1c(ccnc1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cnc(C3CC3)c(C#N)c2c1=O

BDBM545270

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(-c4cccc(n4)C(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545271

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(C)c(C#N)c3c2=O)-c2cccnc2)c2scc(C(O)=O)c2n1

BDBM545272

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3nc(c(C)nc3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545273

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3nc(c(nc3c2=O)-c2ccncc2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545274

Cc1ccc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4ccncc4)c(C#N)c3c2=O)c2scc(C(O)=O)c12

BDBM545275

Cc1cc(ccn1)-c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccc(C)c4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545276

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3nc(c(nc3c2=O)-c2cnccn2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545277

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2ncccn2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545278

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3nc(c(nc3c2=O)N2CCC2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545279

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2ccncn2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545280

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2cncnc2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545281

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2ccnc(C)n2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545282

Cc1nc2cnc(-c3ccncc3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545283

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2c1C

BDBM545284

COc1sc2c(ccnc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cnc(C3CC3)c(C#N)c2c1=O

BDBM545285

Cc1nc2cnc(C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccc(Cl)c2c(csc12)C(O)=O

BDBM545286

CCc1ccc(cn1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545287

Cc1cncc(c1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545289

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cc(F)ccn4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545290

Cc1cc(ccn1)-c1c(F)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545291

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccn(C)n4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545292

CC(=O)c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545293

CN(C)C(=O)c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545294

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)S(C)(=O)=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545295

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)C#C)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545296

CC#Cc1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545297

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)C#N)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545298

CN(C)c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545299

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2ccn(C)n2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545300

Cc1cc(ccn1)-c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccc(C#N)c3c(csc13)C(O)=O)c2=O

BDBM545301

Cc1cc(ccn1)-c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccc(C(N)=O)c3c(csc13)C(O)=O)c2=O

BDBM545302

CN(C)C(=O)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545303

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(C#C)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545304

CN(C)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545305

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(Cl)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545306

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545307

Cc1ccc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c12

BDBM545308

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)C2CC2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545309

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)N2CC(=O)C2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545310

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)N2CC(O)C2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545311

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CCCC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545312

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(C(F)F)c(N4CC(F)(F)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545313

CC1CCN(CC1)c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545314

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)N2CCC(C)(C)CC2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545315

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)N2CCC(F)(F)CC2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545316

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)N2CCC(CC2)C(F)(F)F)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545318

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(F)c(C4=CCCC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1 |t:24|

BDBM545319

CN(C)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cccc(c3)C(O)=O)c(=O)c2c(C#N)c1OC(F)F

BDBM545320

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CC4(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545321

CN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1)c2=O

BDBM545322

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C=C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545323

CN1CCN(CC1)c1cc2c(cn1)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545324

CN1CCN(CC1)c1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1

BDBM545325

CN1CCN(CC1)c1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N

BDBM545326

CCc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545327

CN1CCN(CC1(C)C)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545328

CN1CCN(c2ncc(C#N)c3c2nc(C)n(CCOc2ccc(Cl)cc2-c2ccnc4c(csc24)C(O)=O)c3=O)C(C)(C)C1

BDBM545329

Cc1nc2c(ncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)N1CCN(CCF)C2CC12

BDBM545330

Cc1nc2c(ncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)N1CCN(CC(F)F)C2CC12

BDBM545331

Cc1nc2cnc(OC3CCNCC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545332

Cc1nc2cnc(OC3CCN(CC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545333

CN1CCN(CC1)S(=O)(=O)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545334

Cc1nc2cnc(N3CC4(CN(C4)C4CC4)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545335

Cc1nc2cnc(N3CC4(C3)CN(C4)C(C)(C)C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545336

Cc1nc2cnc(N3CCN(CC(F)F)C4CC34)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545337

Cc1nc2cnc(N3CC4(C3)CN(C4)C3(CF)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545338

Cc1nc2cnc(N3CC4(C3)CN(C4)C(C)(C)CF)c(C#N)c2c(=O)n1CCCc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545339

CN(C1CC2(C1)CN(CC(F)(F)F)C2)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545340

CN(C1CC2(C1)CN(C2)C(C)(C)CF)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545341

CN(C1CC1)C1CC2(C1)CN(C2)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545342

CN(C1CC1)C1CC2(C1)CN(C2)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545343

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(c(C#N)c3c2=O)C2(C)CC2)c2scc(C(O)=O)c2n1

BDBM545344

CN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccccc1)c2=O

BDBM545345

CN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545346

CN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc(C)c1)c2=O

BDBM545347

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4ccsc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545348

Cc1nc2c(ncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)N1CCNCC(F)(F)C1

BDBM545349

CN1CCN(CC(F)(F)C1)c1ncc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545350

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(c(C#N)c3c2=O)C2(CC2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545351

Cc1nc2cnc(N3CC4(CN(CC(F)(F)F)C4)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545352

CN(C)CCOc1cncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c12

BDBM545353

CN1CCN(CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545354

Cc1nc2c(ncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)N1CCN(CCCC(F)(F)F)CC1

BDBM545355

Cc1nc2cnc(N3CCN(CCCC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545356

Cc1nc2cnc(N3CCN(CC3)C(C)(C)CC(F)(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545357

CN1CC(C1)Oc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N

BDBM545358

Cc1ncc(F)cc1-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-4.44,.38,;-5.78,-.38,;-7.11,.38,;-8.44,-.38,;-8.44,-1.93,;-9.78,-2.69,;-7.11,-2.69,;-5.78,-1.93,;-4.44,-2.69,;-4.44,-4.23,;-3.11,-5,;-1.78,-4.23,;-.44,-5,;.89,-4.23,;2.23,-5,;.89,-2.69,;2.23,-1.93,;2.23,-.38,;3.56,.38,;3.56,1.93,;2.23,2.69,;2.23,4.23,;3.56,5,;3.56,6.54,;4.89,4.23,;4.89,2.69,;6.23,1.93,;7.56,2.69,;8.89,1.93,;8.89,.38,;7.56,-.38,;7.24,-1.89,;5.71,-2.05,;5.08,-.65,;6.23,.38,;8.27,-3.04,;9.78,-2.72,;7.8,-4.5,;-.44,-1.93,;-.44,-.38,;-1.78,-2.69,;-3.11,-1.93,;-3.11,-.38,;-3.11,1.15,;-5.78,-5,;-7.11,-4.23,;-5.78,-6.54,;-7.11,-5.78,)|

BDBM545359

CN(C1CCN(C)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N

BDBM545360

CN1CCN(CC1)c1cc2c(nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c2=O)nc1C(F)(F)F

BDBM545361

CCc1nc(C)c2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545362

CCc1nc(C)c2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545363

Cc1nc2cc(c(N3CCN(CCO)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2ccsc12)C(F)(F)F

BDBM545364

Cc1nc2cc(c(OCCN3CCNCC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2ccsc12)C(F)(F)F

BDBM545365

CN(C1CCN(C)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545366

Cc1nc2cc(c(N3CCNCC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2ccsc12)C(F)(F)F

BDBM545367

Cc1cc(-c2cc(Cl)ccc2C#CCn2c(C)nc3cc(c(N4CCN(CCO)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545368

CN1CC2CCC(C1)N2c1ncc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545369

CN(C)CCc1cc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545370

Cc1nc2cc(c(N3CCN(CCO)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545371

Cc1nc2cnc(N3CCN(CC(F)(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545372

CN(C1CCN(CC(F)(F)F)CC1)c1ncc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545373

CN(C1CCN(C)CC1F)c1ncc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545374

CN(C1CC2CCC(C1)N2C)c1ncc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545375

CN(C1CCN(C)C(C1)C(F)F)c1ncc(C#N)c2c1nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545376

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545377

CN(C1CCN(C)C(C1)C(F)F)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545378

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CCS(=O)(=O)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545379

CN1C2CCC1CN(C2)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N

BDBM545380

Cc1sc2c(cc(C)nc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cnc(OC3CNC3)c(C#N)c2c1=O

BDBM545381

Cc1cnc(C)c(c1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4ccsc34)c(=O)c2c1C#N)C(F)(F)F |(-9.34,-2.69,;-8,-1.93,;-8,-.39,;-6.67,.38,;-5.33,-.38,;-4,.38,;-5.33,-1.93,;-6.67,-2.69,;-4,-2.69,;-4,-4.23,;-2.67,-5,;-1.33,-4.23,;,-5,;1.33,-4.23,;2.67,-5,;1.33,-2.69,;2.67,-1.93,;2.67,-.38,;4,.38,;4,1.93,;2.67,2.69,;2.67,4.23,;4,5,;4,6.54,;5.33,4.23,;5.33,2.69,;6.67,1.93,;8,2.7,;9.34,1.93,;9.34,.38,;8,-.38,;7.68,-1.89,;6.15,-2.05,;5.52,-.65,;6.67,.38,;,-1.93,;,-.38,;-1.33,-2.69,;-2.67,-1.93,;-2.67,-.38,;-2.67,1.15,;-5.33,-5,;-6.67,-5.78,;-5.33,-6.54,;-6.67,-4.23,)|

BDBM545382

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(c(C#N)c3c2=O)-c2c(C)cccc2F)c2scc(C(O)=O)c2n1 |(9.34,2.69,;8,1.93,;6.67,2.69,;5.33,1.93,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.93,;2.67,.38,;1.33,-.38,;1.33,-1.93,;,-2.69,;,-4.23,;1.33,-5,;-1.33,-5,;-2.67,-4.23,;-4,-5,;-4,-6.54,;-5.33,-4.23,;-5.33,-2.69,;-4,-1.93,;-4,-.38,;-4,1.15,;-2.67,-2.69,;-1.33,-1.93,;-1.33,-.38,;-6.67,-1.93,;-8,-2.69,;-8,-4.23,;-9.34,-1.93,;-9.34,-.38,;-8,.38,;-6.67,-.38,;-5.33,.38,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.38,;8,.38,)|

BDBM545383

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4c(C)cccc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1 |(9.34,2.69,;8,1.93,;6.67,2.69,;5.33,1.93,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.93,;2.67,.38,;1.33,-.38,;1.33,-1.93,;,-2.69,;,-4.23,;1.33,-5,;-1.33,-5,;-2.67,-4.23,;-4,-5,;-4,-6.54,;-5.33,-4.23,;-5.33,-2.69,;-6.67,-1.93,;-8,-2.69,;-8,-4.23,;-9.34,-1.93,;-9.34,-.38,;-8,.38,;-6.67,-.38,;-5.33,.38,;-4,-1.93,;-4,-.38,;-4,1.15,;-2.67,-2.69,;-1.33,-1.93,;-1.33,-.38,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.38,;8,.38,)|

BDBM545384

Cc1cc(cc(C)n1)-c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545385

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4cnc(N)cc4F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545386

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(Br)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545387

Cc1sc2c(cc(C)nc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(cc2c1=O)C1CCNCC1)C(F)(F)F

BDBM545388

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(N4CCNCC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545389

Cc1sc2c(cc(C)nc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(N3CCNCC3)c(C#N)c2c1=O)C(F)(F)F

BDBM545390

Cc1nc2cc(c(cc2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C1CCNCC1)C(F)(F)F

BDBM545391

CN1CCC(CC1)c1cc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545392

Cc1nc2cnc(C3=CCC(F)(F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |t:7|

BDBM545393

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CC[C@@H](O)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1 |r|

BDBM545394

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CCC(=O)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545395

Cc1nc2cnc(N3CCN(CCF)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545396

Cc1nc2c(C)nc(N3CCN(CC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545397

Cc1sc2c(ccnc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(C3CCNCC3)c(C#N)c2c1=O)C(F)(F)F

BDBM545398

CN1CCC(=CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |c:4|

BDBM545399

Cc1nc2cnc(C3=CCN(CC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |t:7|

BDBM545400

Cc1nc2cnc(OC3CCN(CC(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545401

Cc1nc2cnc(O)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545402

Cc1nc2cnc(N3CC4(CN(CCF)C4)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545403

Cc1nc2cnc(N3CC4(CN(CC(F)F)C4)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545404

Cc1nc2cnc(N3CC4(CN(CCOC(F)(F)F)C4)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545405

Cc1nc2cnc(N3CCN(CC4CC4)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545407

COc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545409

Cc1sc2c(cn(C)c(=O)c2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(C)c(C#N)c2c1=O)C(F)(F)F

BDBM545410

Cc1nc2cnc(C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cnc(C)c2c(csc12)C(O)=O

BDBM545411

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccncc4C)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(9.34,2.69,;8,1.93,;6.67,2.7,;5.33,1.93,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.93,;2.67,.38,;1.33,-.38,;1.33,-1.93,;,-2.69,;,-4.23,;1.33,-5,;-1.33,-5,;-2.67,-4.23,;-4,-5,;-5.33,-4.23,;-5.33,-2.69,;-6.67,-1.93,;-8,-2.69,;-9.34,-1.93,;-9.34,-.39,;-8,.38,;-6.67,-.38,;-5.33,.38,;-4,-1.93,;-4,-.38,;-4,1.15,;-2.67,-2.69,;-1.33,-1.93,;-1.33,-.38,;-6.67,-5,;-8,-5.78,;-6.67,-6.54,;-8,-4.23,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.38,;8,.38,)|

BDBM545412

Cc1cnc(C)c(c1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-10,-2.69,;-8.67,-1.93,;-8.67,-.39,;-7.34,.38,;-6,-.38,;-4.67,.38,;-6,-1.93,;-7.34,-2.69,;-4.67,-2.69,;-4.67,-4.23,;-3.33,-5,;-2,-4.23,;-.67,-5,;.67,-4.23,;2,-5,;.67,-2.69,;2,-1.93,;2,-.38,;3.33,.38,;3.33,1.93,;2,2.69,;2,4.23,;3.33,5,;3.33,6.54,;4.67,4.23,;4.67,2.69,;6,1.93,;7.34,2.7,;8.67,1.93,;10,2.69,;8.67,.38,;7.34,-.38,;7.02,-1.89,;5.48,-2.05,;4.86,-.65,;6,.38,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;-.67,-1.93,;-.67,-.38,;-2,-2.69,;-3.33,-1.93,;-3.33,-.38,;-3.33,1.15,;-6,-5,;-7.34,-5.78,;-6,-6.54,;-7.34,-4.23,)|

BDBM545413

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cncc(C)c4C)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(9.34,2.69,;8,1.93,;6.67,2.7,;5.33,1.93,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.93,;2.67,.38,;1.33,-.38,;1.33,-1.93,;,-2.69,;,-4.23,;1.33,-5,;-1.33,-5,;-2.67,-4.23,;-4,-5,;-5.33,-4.23,;-5.33,-2.69,;-6.67,-1.93,;-8,-2.69,;-9.34,-1.93,;-9.34,-.39,;-8,.38,;-8,1.92,;-6.67,-.38,;-5.33,.38,;-4,-1.93,;-4,-.38,;-4,1.15,;-2.67,-2.69,;-1.33,-1.93,;-1.33,-.38,;-6.67,-5,;-8,-5.78,;-6.67,-6.54,;-8,-4.23,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.38,;8,.38,)|

BDBM545414

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccc(C)c(C)n4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545415

Cc1cc(C)nc(c1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545416

Cc1ccc(C)c(n1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-10,-2.69,;-8.67,-1.93,;-8.67,-.39,;-7.34,.38,;-6,-.38,;-4.67,.38,;-6,-1.93,;-7.34,-2.69,;-4.67,-2.69,;-4.67,-4.23,;-3.33,-5,;-2,-4.23,;-.67,-5,;.67,-4.23,;2,-5,;.67,-2.69,;2,-1.93,;2,-.38,;3.33,.38,;3.33,1.93,;2,2.69,;2,4.23,;3.33,5,;3.33,6.54,;4.67,4.23,;4.67,2.69,;6,1.93,;7.34,2.7,;8.67,1.93,;10,2.69,;8.67,.38,;7.34,-.38,;7.02,-1.89,;5.48,-2.05,;4.86,-.65,;6,.38,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;-.67,-1.93,;-.67,-.38,;-2,-2.69,;-3.33,-1.93,;-3.33,-.38,;-3.33,1.15,;-6,-5,;-7.34,-5.78,;-6,-6.54,;-7.34,-4.23,)|

BDBM545417

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cn(C)cn4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545418

Cc1cc(-c2cc(Cl)ccc2C#CCn2c(C)nc3cc(c(-c4ccncn4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545419

CN(C)C(=O)Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545420

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(nc(C4CC4)c(C#N)c3c2=O)-c2ccccc2)c2scc(C(O)=O)c2n1

BDBM545421

Cc1cc(ccn1)-c1nc(C)c2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545422

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CCC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545423

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(c(C#N)c3c2=O)C(C)(F)F)c2scc(C(O)=O)c2n1

BDBM545424

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545425

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(CF)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545427

Cc1nc2cnc(C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cc(CF)nc2c(csc12)C(O)=O

BDBM545428

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CCC4(C)C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545429

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CCC(F)(F)CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545430

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CCCC4(C)C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545431

Cc1ncc(s1)-c1c(F)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545432

Cc1nc2cnc(C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1Sc1nc(cs1)C(O)=O

BDBM545433

CCc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545434

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4ccccc4C(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545435

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4cccc(c4)C(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545436

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4ccc(cc4)C(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545437

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4cc(F)ccc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545438

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CC(F)(F)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545439

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CCCC4(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545440

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CCC(F)(F)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545441

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CCCC(F)(F)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545442

Cc1cc(cc(C)n1)-c1c(F)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545443

Cc1cc(cc(C)n1)-c1c(CF)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545444

Cc1cc(cc(CF)n1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545445

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(F)c(-c4ccccc4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545447

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)C(C)(C)O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545449

Cc1nc2cnc(C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1Sc1cccc(n1)C(O)=O

BDBM545450

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4ccccc4F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545451

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4cccc(F)c4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545452

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4ccc(F)cc4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545453

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4ccccc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545454

Cc1cccc(c1)-c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545455

Cc1ccc(cc1)-c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545456

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4ccccc4Cl)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545457

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4cccc(Cl)c4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545458

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4ccc(Cl)cc4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545459

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4ccccc4C(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545460

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4cccc(c4)C(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545461

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4ccc(cc4)C(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545462

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4cc(Cl)ccc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545463

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4cc(Cl)ccc4Cl)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545464

CN(c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(C)(C)C

BDBM545465

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(NC(C)(C)C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545466

CN(C1CC1)c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545467

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(NC4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545468

CN(c1ccc(C)nc1)c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545469

Cc1ccc(Nc2c(Cl)cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)cn1

BDBM545470

CN(c1cncc(F)c1)c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545471

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(Nc4cncc(F)c4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545472

Cc1cc(nc(C)n1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545473

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4nc(C)ncc4F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(10,2.69,;8.67,1.93,;7.34,2.7,;6,1.93,;4.67,2.69,;4.67,4.23,;3.33,5,;3.33,6.54,;2,4.23,;2,2.69,;3.33,1.93,;3.33,.38,;2,-.38,;2,-1.93,;.67,-2.69,;.67,-4.23,;2,-5,;-.67,-5,;-2,-4.23,;-3.33,-5,;-4.67,-4.23,;-4.67,-2.69,;-6,-1.93,;-7.34,-2.69,;-8.67,-1.93,;-10,-2.69,;-8.67,-.38,;-7.34,.38,;-6,-.38,;-4.67,.38,;-3.33,-1.93,;-3.33,-.38,;-3.33,1.15,;-2,-2.69,;-.67,-1.93,;-.67,-.38,;-6,-5,;-7.34,-5.78,;-6,-6.54,;-7.34,-4.23,;6,.38,;4.86,-.65,;5.48,-2.05,;7.02,-1.89,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;7.34,-.38,;8.67,.38,)|

BDBM545474

Cc1cc(C)nc(n1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545475

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ncc(F)cn4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545476

Cc1ccc(nn1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545477

Cc1cnc(C)c(n1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-10,-2.69,;-8.67,-1.93,;-8.67,-.38,;-7.34,.38,;-6,-.38,;-4.67,.38,;-6,-1.93,;-7.34,-2.69,;-4.67,-2.69,;-4.67,-4.23,;-3.33,-5,;-2,-4.23,;-.67,-5,;.67,-4.23,;2,-5,;.67,-2.69,;2,-1.93,;2,-.38,;3.33,.38,;3.33,1.93,;2,2.69,;2,4.23,;3.33,5,;3.33,6.54,;4.67,4.23,;4.67,2.69,;6,1.93,;7.34,2.7,;8.67,1.93,;10,2.69,;8.67,.38,;7.34,-.38,;7.02,-1.89,;5.48,-2.05,;4.86,-.65,;6,.38,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;-.67,-1.93,;-.67,-.38,;-2,-2.69,;-3.33,-1.93,;-3.33,-.38,;-3.33,1.15,;-6,-5,;-7.34,-5.78,;-6,-6.54,;-7.34,-4.23,)|

BDBM545478

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cnc(C)c(C)n4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545479

Cc1nc2cnc(C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1Cc1cc(cs1)C(O)=O

BDBM545480

CN(CC(F)(F)F)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545481

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(NCC(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545482

CN(CC(F)F)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545483

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(NCC(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545484

CN(CCO)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545485

CON(C)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545486

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CCCC4=O)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545487

CN(C)N(C)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545488

CN(C)Nc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545489

COC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cnc(N(C)C3CCN(CC(C)(F)F)CC3)c(C#N)c2c1=O

BDBM545490

CN(C)c1ncc2nc(C(F)F)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545491

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CCc5ccccc45)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545492

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(c(C#N)c3c2=O)-n2ccc3ccccc23)c2scc(C(O)=O)c2n1

BDBM545493

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(c(C#N)c3c2=O)-n2cccn2)c2scc(C(O)=O)c2n1

BDBM545494

CNc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545495

CN(c1ccccc1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545496

CN(C)c1nc(-c2ccccc2)c2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545497

COC(C)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545498

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C(=C)C(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545499

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2nccnc2C(F)(F)F)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545500

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CCC(Cl)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545501

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CCSCC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545502

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4ccc5ncsc5c4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545503

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CC4C(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545504

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4nc(ccc4F)C(F)F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(10.67,2.69,;9.34,1.93,;8,2.7,;6.67,1.93,;5.33,2.69,;5.33,4.23,;4,5,;4,6.54,;2.67,4.23,;2.67,2.69,;4,1.93,;4,.38,;2.67,-.38,;2.67,-1.93,;1.33,-2.69,;1.33,-4.23,;2.67,-5,;,-5,;-1.33,-4.23,;-2.67,-5,;-4,-4.23,;-4,-2.69,;-5.33,-1.93,;-6.67,-2.69,;-8,-1.93,;-8,-.38,;-6.67,.38,;-5.33,-.38,;-4,.39,;-9.34,-2.69,;-9.34,-4.23,;-10.67,-1.93,;-2.67,-1.93,;-2.67,-.38,;-2.67,1.15,;-1.33,-2.69,;,-1.93,;,-.38,;-5.33,-5,;-6.67,-5.78,;-5.33,-6.54,;-6.67,-4.23,;6.67,.38,;5.52,-.65,;6.15,-2.05,;7.68,-1.89,;8.71,-3.04,;8.24,-4.5,;10.22,-2.72,;8,-.38,;9.34,.38,)|

BDBM545505

CN(C)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545506

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4cc(Cl)ccc4F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545507

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4cc(F)ccc4F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545508

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4cc(F)ccc4Cl)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545509

Cc1ccc(F)c(n1)-c1ncc2cc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545510

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)cc3cnc(-c4cc(F)cnc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545511

CN(C)c1ncc2cc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545512

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)cc3cnc(N4CCC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545513

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(O)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545514

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cn(C)c(=O)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545515

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(-c4ncco4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545516

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c[n+]([O-])c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545517

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(nc(N4CCC4)c(C#N)c3c2=O)-c2ccccc2)c2scc(C(O)=O)c2n1

BDBM545518

COC1CN(C1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545519

COC1CN(C1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545520

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CC(O)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545521

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccncc4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545522

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cccnc4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545523

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccn(C)n4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545524

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(-c4ccccc4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545525

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4ccccc4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545526

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cc(F)cnc4C)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(10.67,1.93,;9.34,2.7,;8,1.93,;6.67,2.7,;5.34,1.93,;4,2.7,;4,4.24,;2.67,5.01,;2.67,6.55,;1.34,4.24,;1.34,2.7,;2.67,1.93,;2.67,.38,;1.33,-.39,;1.33,-1.93,;-0,-2.7,;-0,-4.24,;1.33,-5.01,;-1.34,-5.01,;-2.67,-4.24,;-4,-5.01,;-5.34,-4.24,;-5.34,-2.7,;-6.67,-1.93,;-8,-2.7,;-9.34,-1.93,;-10.67,-2.7,;-9.34,-.39,;-8,.38,;-6.67,-.39,;-5.34,.38,;-4,-1.93,;-4,-.39,;-4,1.15,;-2.67,-2.7,;-1.34,-1.93,;-1.34,-.39,;-6.67,-5.01,;-8,-4.24,;-6.67,-6.55,;-8,-5.78,;5.34,.39,;4.19,-.64,;4.82,-2.04,;6.35,-1.88,;7.38,-3.03,;6.9,-4.49,;8.89,-2.71,;6.67,-.38,;8,.39,)|

BDBM545527

Cc1cnc(cn1)-c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545528

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2nccnc2C)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545529

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2cnc(cn2)C(F)F)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545530

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)-c2cncc(n2)C(F)(F)F)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545531

Cc1cnc(C)c(n1)-c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545532

Cc1cnc(c(C)n1)-c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545533

Cc1cnc(c(Cl)n1)-c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545534

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cnc(cn4)C(F)F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545535

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cncc(n4)C(F)(F)F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545536

Cc1cn(C)nc1-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-5.04,.63,;-6.18,-.4,;-7.69,-.08,;-8.46,-1.42,;-9.99,-1.58,;-7.43,-2.56,;-6.02,-1.93,;-4.69,-2.7,;-4.69,-4.24,;-3.35,-5.01,;-2.02,-4.24,;-.69,-5.01,;.65,-4.24,;1.98,-5.01,;.65,-2.7,;1.98,-1.93,;1.98,-.39,;3.32,.38,;3.32,1.93,;1.99,2.7,;1.99,4.24,;3.32,5.01,;3.32,6.55,;4.65,4.24,;4.65,2.7,;5.99,1.93,;7.32,2.7,;8.66,1.93,;9.99,2.7,;8.66,.39,;7.32,-.38,;7,-1.88,;5.47,-2.04,;4.84,-.64,;5.99,.39,;8.03,-3.03,;7.56,-4.49,;9.54,-2.71,;-.69,-1.93,;-.69,-.39,;-2.02,-2.7,;-3.35,-1.93,;-3.35,-.39,;-3.35,1.15,;-6.02,-5.01,;-7.35,-4.24,;-6.02,-6.55,;-7.35,-5.78,)|

BDBM545537

Cc1cc(-c2c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)C(F)(F)F)n(C)n1 |(-9.99,-1.58,;-8.46,-1.42,;-7.43,-2.56,;-6.02,-1.93,;-4.69,-2.7,;-4.69,-4.24,;-3.35,-5.01,;-2.02,-4.24,;-.69,-5.01,;.65,-4.24,;1.98,-5.01,;.65,-2.7,;1.98,-1.93,;1.98,-.39,;3.32,.38,;3.32,1.93,;1.99,2.7,;1.99,4.24,;3.32,5.01,;3.32,6.55,;4.65,4.24,;4.65,2.7,;5.99,1.93,;7.32,2.7,;8.66,1.93,;9.99,2.7,;8.66,.39,;7.32,-.38,;7,-1.88,;5.47,-2.04,;4.84,-.64,;5.99,.39,;8.03,-3.03,;7.56,-4.49,;9.54,-2.71,;-.69,-1.93,;-.69,-.39,;-2.02,-2.7,;-3.35,-1.93,;-3.35,-.39,;-3.35,1.15,;-6.02,-5.01,;-7.35,-4.24,;-6.02,-6.55,;-7.35,-5.78,;-6.18,-.4,;-5.04,.63,;-7.69,-.08,)|

BDBM545538

Cc1cc(nn1C)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545539

Cc1cnn(C)c1-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-8.61,-4.07,;-8.29,-2.56,;-9.32,-1.42,;-8.55,-.08,;-7.05,-.4,;-5.9,.63,;-6.89,-1.93,;-5.35,-2.7,;-5.35,-4.24,;-4.02,-5.01,;-2.69,-4.24,;-1.35,-5.01,;-.02,-4.24,;1.32,-5.01,;-.02,-2.7,;1.32,-1.93,;1.32,-.39,;2.65,.38,;2.65,1.93,;1.32,2.7,;1.32,4.24,;2.65,5.01,;2.65,6.55,;3.99,4.24,;3.99,2.7,;5.32,1.93,;6.65,2.7,;7.99,1.93,;9.32,2.7,;7.99,.39,;6.65,-.38,;6.33,-1.88,;4.8,-2.04,;4.18,-.64,;5.32,.39,;7.37,-3.03,;6.89,-4.49,;8.87,-2.71,;-1.35,-1.93,;-1.35,-.39,;-2.69,-2.7,;-4.02,-1.93,;-4.02,-.39,;-4.02,1.15,;-6.69,-5.01,;-8.02,-4.24,;-6.69,-6.55,;-8.02,-5.78,)|

BDBM545540

Cc1nn(C)cc1-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-5.04,.63,;-6.18,-.4,;-7.69,-.08,;-8.46,-1.42,;-9.99,-1.58,;-7.43,-2.56,;-6.02,-1.93,;-4.69,-2.7,;-4.69,-4.24,;-3.35,-5.01,;-2.02,-4.24,;-.69,-5.01,;.65,-4.24,;1.98,-5.01,;.65,-2.7,;1.98,-1.93,;1.98,-.39,;3.32,.38,;3.32,1.93,;1.99,2.7,;1.99,4.24,;3.32,5.01,;3.32,6.55,;4.65,4.24,;4.65,2.7,;5.99,1.93,;7.32,2.7,;8.66,1.93,;9.99,2.7,;8.66,.39,;7.32,-.38,;7,-1.88,;5.47,-2.04,;4.84,-.64,;5.99,.39,;8.03,-3.03,;7.56,-4.49,;9.54,-2.71,;-.69,-1.93,;-.69,-.39,;-2.02,-2.7,;-3.35,-1.93,;-3.35,-.39,;-3.35,1.15,;-6.02,-5.01,;-7.35,-4.24,;-6.02,-6.55,;-7.35,-5.78,)|

BDBM545541

Cc1c(cnn1C)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-5.8,.63,;-6.95,-.4,;-6.79,-1.93,;-8.19,-2.56,;-9.22,-1.42,;-8.45,-.08,;-9.08,1.32,;-5.45,-2.7,;-5.45,-4.24,;-4.12,-5.01,;-2.78,-4.24,;-1.45,-5.01,;-.12,-4.24,;1.22,-5.01,;-.12,-2.7,;1.22,-1.93,;1.22,-.39,;2.55,.38,;2.55,1.93,;1.22,2.7,;1.22,4.24,;2.55,5.01,;2.55,6.55,;3.89,4.24,;3.89,2.7,;5.22,1.93,;6.56,2.7,;7.89,1.93,;9.22,2.7,;7.89,.39,;6.56,-.38,;6.24,-1.88,;4.7,-2.04,;4.08,-.64,;5.22,.39,;7.27,-3.03,;6.79,-4.49,;8.77,-2.71,;-1.45,-1.93,;-1.45,-.39,;-2.78,-2.7,;-4.12,-1.93,;-4.12,-.39,;-4.12,1.15,;-6.79,-5.01,;-8.12,-4.24,;-6.79,-6.55,;-8.12,-5.78,)|

BDBM545542

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(OCc4ccccn4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545543

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(OC4CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545544

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(Oc4cccnc4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545545

COc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545546

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(OC4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545547

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(Oc4ccccc4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545548

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(OCc4ccccn4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545549

CN(C)c1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1-c1ccccc1

BDBM545550

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CC(C4)OC(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545551

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CC(C4)OC(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545552

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CC(C4)OCC(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545553

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CC(C4)OCC(F)(F)F)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545554

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CC(C4)OC(C)(C)C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545555

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(C4CCC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545556

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(C4CCC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545557

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(C(F)F)c(C4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545558

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(C4CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545559

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(C4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545560

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4cc(F)cnc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545561

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4cc(F)ccc4C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545562

CN(C(C)=O)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545563

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CCC(O)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545564

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CC(C)(O)C4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545565

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CCC(O)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545566

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CC(C)(O)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545567

Cc1cc(cc(C)n1)-c1c(cc2nc(C)n(CCOc3cc(F)c(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545568

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccc(Cl)nc4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545569

COc1cncc(c1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545570

COc1ccc(cn1)-c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545571

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(CC)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545572

CCCc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545573

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(CCF)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545574

CC(F)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545575

COCc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545576

CCOc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545577

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(OCC4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545578

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(N)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545579

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(N)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545580

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545581

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545582

CCOc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545583

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(OCC(F)(F)F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545584

CN1CCN(C(=O)C1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545585

CCCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(C4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545586

CCc1cc(-c2cc(Cl)ccc2OCCn2c(N)nc3cc(Cl)cc(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545587

CCc1cc(-c2cc(Cl)ccc2OCCn2c(=O)[nH]c3cc(Cl)cc(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545588

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)(O)C(F)(F)F)c(=O)c2c1C#N)C(F)(F)F

BDBM545589

CN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)C(F)(F)F)c2=O

BDBM545590

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cc(F)cnc4C)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(=O)OCCN3CCCC3)c2n1 |(9.35,4.69,;8.01,3.92,;6.68,4.69,;5.35,3.92,;4.01,4.69,;4.01,6.23,;2.68,7,;2.68,8.54,;1.35,6.23,;1.35,4.69,;2.68,3.92,;2.68,2.38,;1.35,1.61,;1.35,.07,;.01,-.7,;.01,-2.24,;1.35,-3.01,;-1.32,-3.01,;-2.66,-2.24,;-3.99,-3.01,;-5.32,-2.24,;-5.32,-.7,;-6.66,.07,;-7.99,-.7,;-9.32,.07,;-10.66,-.7,;-9.32,1.61,;-7.99,2.38,;-6.66,1.61,;-5.32,2.38,;-3.99,.07,;-3.99,1.61,;-3.99,3.15,;-2.66,-.7,;-1.32,.07,;-1.32,1.61,;-6.66,-3.01,;-7.99,-3.78,;-6.66,-4.55,;-7.99,-2.24,;5.35,2.38,;4.2,1.35,;4.83,-.06,;6.36,.1,;7.39,-1.04,;8.9,-.72,;6.91,-2.51,;7.95,-3.65,;7.47,-5.12,;8.5,-6.26,;8.18,-7.77,;9.51,-8.54,;10.66,-7.51,;10.03,-6.1,;6.68,1.61,;8.01,2.38,)|

BDBM545591

CC(OC(=O)OC1CCCCC1)OC(=O)c1csc2c(cc(C)nc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(N3CCN(C)CC3)c(C#N)c2c1=O)C(F)(F)F

BDBM545592

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(cc3c2=O)N2CCN(C)CC2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545593

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(nc3c2=O)N2CCN(C)CC2)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545594

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CCN(C)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545595

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CCN(C)CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545596

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CCN(C)CC4)c(C#N)c3c2=O)C(F)(F)F)c2sc(C)c(C(O)=O)c2n1

BDBM545597

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(C4=CCN(C)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |t:24|

BDBM545598

CN1CCN(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4ccsc34)c(=O)c2c1C#N

BDBM545599

C[C@H]1CN(C[C@@H](C)N1C)c1c(Cl)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N |r|

BDBM545600

C[C@H]1CN(C[C@@H](C)N1C)c1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c(C#N)c1F |r|

BDBM545601

CN(C)C1CN(C1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N

BDBM545602

CN1C[C@@H]2CC[C@H](C1)N2c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N |r,THB:9:8:7.1.2:4.5|

BDBM545603

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545604

CN1CCN(CC1)c1cc2c(cc1Cl)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545605

CN1CCN(CC1)c1cc2c(cc1F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545606

CN1CCN(CC1)c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(C(O)=O)c(C)sc13)c2=O

BDBM545607

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CCC(F)(F)CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545608

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(Cl)c(C#N)c3c2=O)-c2cccnc2)c2scc(C(O)=O)c2n1

BDBM545609

CN([C@H]1CC[C@@H](CC1)N1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:2.1,wD:5.8,(-7.78,-4.07,;-6.44,-3.3,;-6.44,-1.76,;-7.78,-.99,;-7.78,.55,;-6.44,1.32,;-5.11,.55,;-5.11,-.99,;-6.44,2.86,;-5.35,3.95,;-6.44,5.04,;-7.21,6.38,;-5.67,6.38,;-7.53,3.95,;-5.11,-4.07,;-5.11,-5.61,;-3.78,-6.38,;-2.44,-5.61,;-1.11,-6.38,;.23,-5.61,;1.56,-6.38,;.23,-4.07,;1.56,-3.3,;1.56,-1.76,;1.56,-.22,;1.56,1.32,;.23,2.09,;.23,3.63,;1.56,4.4,;1.56,5.94,;2.89,3.63,;2.89,2.09,;4.23,1.32,;5.56,2.09,;6.89,1.32,;6.89,-.22,;5.56,-.99,;5.24,-2.49,;3.71,-2.65,;3.08,-1.25,;4.23,-.22,;6.27,-3.64,;5.79,-5.1,;7.78,-3.32,;-1.11,-3.3,;-1.11,-1.76,;-2.44,-4.07,;-3.78,-3.3,;-3.78,-1.76,;-3.78,-.22,)|

BDBM545610

CN([C@H]1CC[C@H](CC1)N1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:2.1,5.8,(-7.78,-4.07,;-6.44,-3.3,;-6.44,-1.76,;-7.78,-.99,;-7.78,.55,;-6.44,1.32,;-5.11,.55,;-5.11,-.99,;-6.44,2.86,;-5.35,3.95,;-6.44,5.04,;-7.21,6.38,;-5.67,6.38,;-7.53,3.95,;-5.11,-4.07,;-5.11,-5.61,;-3.78,-6.38,;-2.44,-5.61,;-1.11,-6.38,;.23,-5.61,;1.56,-6.38,;.23,-4.07,;1.56,-3.3,;1.56,-1.76,;1.56,-.22,;1.56,1.32,;.23,2.09,;.23,3.63,;1.56,4.4,;1.56,5.94,;2.89,3.63,;2.89,2.09,;4.23,1.32,;5.56,2.09,;6.89,1.32,;6.89,-.22,;5.56,-.99,;5.24,-2.49,;3.71,-2.65,;3.08,-1.25,;4.23,-.22,;6.27,-3.64,;5.79,-5.1,;7.78,-3.32,;-1.11,-3.3,;-1.11,-1.76,;-2.44,-4.07,;-3.78,-3.3,;-3.78,-1.76,;-3.78,-.22,)|

BDBM545611

Cc1nc2cnc(N3CCN(CC3(C)C)C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545612

Cc1nc2cnc(N3CCN(CC3(C)C)C3CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545613

CN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545614

COC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cnc(N3CCN(CCOC(F)(F)F)CC3)c(C#N)c2c1=O

BDBM545615

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC(F)F)c(=O)c2c1C#N

BDBM545616

CN(CCF)C12CCC(CC1)(C2)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545617

CN(C1CCN(CC(F)(F)C(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545618

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N

BDBM545619

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N

BDBM545620

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cccnc3)c(=O)c2c1C#N

BDBM545621

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccncc3)c(=O)c2c1C#N

BDBM545622

CN(C1CCN(CC(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545623

COC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cnc(N(C)C3CCN(CC(F)F)CC3)c(C#N)c2c1=O

BDBM545624

CN(C1CCN(CC(C)(F)F)CC1)c1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1

BDBM545625

Cc1nc2c(ncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C1CCN(CC(F)(F)F)CC1

BDBM545626

Cc1nc2cnc(C3CCN(CC(F)(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545627

Cc1nc2cnc(C3CCN(CC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545628

CN(C1CCN(CC1)C1(C)COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545629

CN(C1CCN(CC(F)(F)C(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545630

CN(C1CCCCC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545631

Cc1nc2cnc(\C=C\CN3CCC(F)(F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545632

Cc1nc2cnc(\C=C\CN3CC(F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545633

CN(C)C1(CC1)\C=C\c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545634

CC(F)CN(C)C1(CC1)\C=C\c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545635

CN(C1CCN(CC(F)(F)C2CC2)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545636

CN(C1CCN(CC(F)(F)C2CC2)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545637

CC(C)C(=O)CN1CCC(CC1)N(C)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545638

CN(C1CCN(CC(=O)C2CC2)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545639

CC(C)C(F)(F)CN1CCC(CC1)N(C)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545640

CN(C1CCN(CC(O)(F)C(C)(C)O)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545641

CN(C1CCN(CC1)C1(CC1)C(F)(F)CO)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545642

CN(C1CCN(CC(F)(F)CO)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545643

COCC(F)(F)CN1CCC(CC1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545644

CN(C1CCN(CC(F)(F)CF)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545645

CN(C1CCN(CC1)[C@H]1C[C@@H](C1)OC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:8.8,wD:10.13,(-7.11,-5.32,;-5.78,-4.55,;-5.78,-3.01,;-4.44,-2.24,;-4.44,-.7,;-5.78,.07,;-7.11,-.7,;-7.11,-2.24,;-5.78,1.61,;-6.87,2.7,;-5.78,3.78,;-4.69,2.7,;-5.78,5.32,;-7.11,6.09,;-7.11,7.63,;-8.44,5.32,;-4.44,-5.32,;-4.44,-6.86,;-3.11,-7.63,;-1.78,-6.86,;-.44,-7.63,;.89,-6.86,;2.23,-7.63,;.89,-5.32,;2.23,-4.55,;2.23,-3.01,;2.23,-1.47,;2.23,.07,;.89,.84,;.89,2.38,;2.23,3.15,;2.23,4.69,;3.56,2.38,;3.56,.84,;4.89,.07,;6.23,.84,;7.56,.07,;7.56,-1.47,;6.23,-2.24,;5.91,-3.75,;4.38,-3.91,;3.75,-2.5,;4.89,-1.47,;6.94,-4.89,;6.46,-6.36,;8.44,-4.57,;-.44,-4.55,;-.44,-3.01,;-1.78,-5.32,;-3.11,-4.55,;-3.11,-3.01,;-3.11,-1.47,)|

BDBM545646

Cc1nc2cnc(N3CCC4(CN(CC(F)F)C4)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545647

Cc1nc2cnc(N3CCC4(CN(CC(C)(F)F)C4)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545648

CN(C)CCc1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N

BDBM545649

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545650

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545651

CN(C1CCN(CC(C)(C)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545652

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccncc3)c(=O)c2c1C#N

BDBM545653

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cccnc3)c(=O)c2c1C#N

BDBM545654

CN1CCN(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545655

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N

BDBM545656

Cc1nc2cccc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O

BDBM545657

Cc1nc2c(C)nc(-c3ccccc3C(F)(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545658

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(N4CCC(O)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545659

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)S(C)(=O)=O

BDBM545660

CN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(=O)NS(C)(=O)=O)c2=O

BDBM545661

CO[C@H]1C[C@H](C1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wD:4.6,2.1,(-10.28,-1.61,;-8.95,-.84,;-7.61,-1.61,;-7.21,-3.09,;-5.73,-2.69,;-6.12,-1.21,;-4.39,-3.47,;-4.39,-5,;-3.06,-5.78,;-1.72,-5,;-.39,-5.78,;.94,-5,;2.28,-5.78,;.94,-3.47,;2.28,-2.69,;2.28,-1.15,;3.61,-.38,;3.61,1.15,;2.28,1.93,;2.28,3.47,;3.61,4.23,;3.61,5.78,;4.94,3.47,;4.94,1.93,;6.28,1.15,;7.61,1.93,;8.95,1.15,;10.28,1.93,;8.95,-.38,;7.61,-1.15,;7.29,-2.66,;5.76,-2.82,;5.13,-1.42,;6.28,-.38,;8.32,-3.81,;7.85,-5.27,;9.83,-3.49,;-.39,-2.69,;-.39,-1.15,;-1.72,-3.47,;-3.06,-2.69,;-3.06,-1.15,;-3.06,.38,)|

BDBM545662

Cc1nc2cc(c(OCC(F)(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545663

CN1CCN(CC1)c1c(cc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3cccc(c3)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545664

CN1CCN(CC1)c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(=O)NS(C)(=O)=O)c2=O

BDBM545665

Cc1nc2cc(c(N3CCN(CCC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCCc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545666

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N

BDBM545667

Cc1nc2cc(c(N3CC4(CN(C4)C4CC4)C3)c(C#N)c2c(=O)n1CCCc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545668

Cc1nc2cc(c(N3CCN(CC3)C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O)C(F)(F)F

BDBM545669

Cc1nc2cnc(N3CCN(CCC(F)(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545670

Cc1nc2cnc(N3CCN(CCOC(F)(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545671

Cc1nc2cnc(N3CCN(CC3)C3CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545672

Cc1nc2cnc(N3CCN(CC3)C3CC(F)(F)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545673

Cc1nc2cnc(N3CCN(CC(C)(F)CF)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545674

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545675

CN(C1CCN(CC1)C1CCC1(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545676

Cc1nc2cnc(N3CCN(CC4(F)CC4)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545677

CCC(F)(F)CN1CCC(CC1)N(C)c1ncc2nc(C)n(COCc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545678

CN(C1CCN(CC2(F)CC2)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545679

CN(C1CCN(CCOC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545680

CN(C1CCN(CC1)C1CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545681

CN(C1CCN(CC1)[C@@H]1C[C@@H](C1)OC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:8.8,10.13,(-7.11,-5.32,;-5.78,-4.55,;-5.78,-3.01,;-4.44,-2.24,;-4.44,-.7,;-5.78,.07,;-7.11,-.7,;-7.11,-2.24,;-5.78,1.61,;-4.69,2.7,;-5.78,3.78,;-6.87,2.7,;-5.78,5.32,;-7.11,6.09,;-7.11,7.63,;-8.44,5.32,;-4.44,-5.32,;-4.44,-6.86,;-3.11,-7.63,;-1.78,-6.86,;-.44,-7.63,;.89,-6.86,;2.23,-7.63,;.89,-5.32,;2.23,-4.55,;2.23,-3.01,;2.23,-1.47,;2.23,.07,;.89,.84,;.89,2.38,;2.23,3.15,;2.23,4.69,;3.56,2.38,;3.56,.84,;4.89,.07,;6.23,.84,;7.56,.07,;7.56,-1.47,;6.23,-2.24,;5.91,-3.75,;4.38,-3.91,;3.75,-2.5,;4.89,-1.47,;6.94,-4.89,;6.46,-6.36,;8.44,-4.57,;-.44,-4.55,;-.44,-3.01,;-1.78,-5.32,;-3.11,-4.55,;-3.11,-3.01,;-3.11,-1.47,)|

BDBM545682

CN(C1CCN(CC1)[C@@H]1C[C@@H](C1)OC(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:8.8,10.13,(-7.11,-5.32,;-5.78,-4.55,;-5.78,-3.01,;-4.44,-2.24,;-4.44,-.7,;-5.78,.07,;-7.11,-.7,;-7.11,-2.24,;-5.78,1.61,;-4.69,2.7,;-5.78,3.78,;-6.87,2.7,;-5.78,5.32,;-7.11,6.09,;-7.11,7.63,;-8.44,5.32,;-8.44,6.86,;-4.44,-5.32,;-4.44,-6.86,;-3.11,-7.63,;-1.78,-6.86,;-.44,-7.63,;.89,-6.86,;2.23,-7.63,;.89,-5.32,;2.23,-4.55,;2.23,-3.01,;2.23,-1.47,;2.23,.07,;.89,.84,;.89,2.38,;2.23,3.15,;2.23,4.69,;3.56,2.38,;3.56,.84,;4.89,.07,;6.23,.84,;7.56,.07,;7.56,-1.47,;6.23,-2.24,;5.91,-3.75,;4.38,-3.91,;3.75,-2.5,;4.89,-1.47,;6.94,-4.89,;6.46,-6.36,;8.44,-4.57,;-.44,-4.55,;-.44,-3.01,;-1.78,-5.32,;-3.11,-4.55,;-3.11,-3.01,;-3.11,-1.47,)|

BDBM545683

COCCC(CCOC)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545684

CN(C1CCN(CC2(F)CCC2)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545685

CN(C1CCN(CC1)[C@@H]1C[C@H]1C(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM545686

CCN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545687

CCN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545688

CC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cc(c(N3CC4(CN(C4)C4CC4)C3)c(C#N)c2c1=O)C(F)(F)F

BDBM545690

Cc1nc2cnc(N3CCC(CC3)N3CCC(F)(F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545691

CN(C1CCN(CC1)C1C[C@H](F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wD:10.11,(-7.78,-4.17,;-6.44,-3.4,;-6.44,-1.86,;-5.11,-1.09,;-5.11,.45,;-6.44,1.22,;-7.78,.45,;-7.78,-1.09,;-6.44,2.76,;-7.53,3.85,;-6.44,4.94,;-6.44,6.48,;-5.35,3.85,;-5.11,-4.17,;-5.11,-5.71,;-3.78,-6.48,;-2.44,-5.71,;-1.11,-6.48,;.23,-5.71,;1.56,-6.48,;.23,-4.17,;1.56,-3.4,;1.56,-1.86,;1.56,-.32,;1.56,1.22,;.23,1.99,;.23,3.53,;1.56,4.3,;1.56,5.84,;2.89,3.53,;2.89,1.99,;4.23,1.22,;5.56,1.99,;6.89,1.22,;6.89,-.32,;5.56,-1.09,;5.24,-2.6,;3.71,-2.76,;3.08,-1.35,;4.23,-.32,;6.27,-3.74,;5.79,-5.2,;7.78,-3.42,;-1.11,-3.4,;-1.11,-1.86,;-2.44,-4.17,;-3.78,-3.4,;-3.78,-1.86,;-3.78,-.32,)|

BDBM545692

CN(C1CCN(CC1)C1(COC1)C(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545693

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3COC3)c(=O)c2c1C#N

BDBM545694

CCN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545695

CN(C1CCN(CC2(F)COC2)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545696

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545697

Cc1nc2cnc(N3CCC(CC3)N3CC(C3)OC(F)F)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545699

CN(C1CCN(CC2CC(C2)OC(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |(-5.5,-4.78,;-4.17,-4.01,;-4.17,-2.47,;-2.83,-1.7,;-2.83,-.16,;-4.17,.61,;-4.17,2.15,;-5.5,2.92,;-5.9,4.41,;-7.39,4.01,;-6.99,2.52,;-8.72,4.78,;-8.72,6.32,;-7.39,7.09,;-10.05,7.09,;-5.5,-.16,;-5.5,-1.7,;-2.83,-4.78,;-2.83,-6.32,;-1.5,-7.09,;-.17,-6.32,;1.17,-7.09,;2.5,-6.32,;3.84,-7.09,;2.5,-4.78,;3.84,-4.01,;3.84,-2.47,;3.84,-.93,;3.84,.61,;2.5,1.38,;2.5,2.92,;3.84,3.69,;3.84,5.23,;5.17,2.92,;5.17,1.38,;6.5,.61,;7.84,1.38,;9.17,.61,;9.17,-.93,;7.84,-1.7,;7.52,-3.21,;5.99,-3.37,;5.36,-1.96,;6.5,-.93,;8.55,-4.35,;8.07,-5.81,;10.05,-4.03,;1.17,-4.01,;1.17,-2.47,;-.17,-4.78,;-1.5,-4.01,;-1.5,-2.47,;-1.5,-.93,)|

BDBM545700

CN(C1CCN(CCC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545701

CCN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545702

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccnc5NCCc45)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(9.34,2.69,;8,1.93,;6.67,2.69,;5.33,1.93,;4,2.69,;4,4.23,;2.67,5,;2.67,6.54,;1.33,4.23,;1.33,2.69,;2.67,1.93,;2.67,.38,;1.33,-.38,;1.33,-1.93,;,-2.69,;,-4.23,;1.33,-5,;-1.33,-5,;-2.67,-4.23,;-4,-5,;-5.33,-4.23,;-5.33,-2.69,;-6.67,-1.93,;-8,-2.69,;-9.34,-1.93,;-9.34,-.38,;-8,.38,;-7.68,1.89,;-6.15,2.05,;-5.52,.65,;-6.67,-.38,;-4,-1.93,;-4,-.38,;-4,1.15,;-2.67,-2.69,;-1.33,-1.93,;-1.33,-.38,;-6.67,-5,;-8,-5.78,;-6.67,-6.54,;-8,-4.23,;5.33,.38,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;6.9,-4.5,;8.88,-2.72,;6.67,-.38,;8,.38,)|

BDBM545703

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(c(C#N)c(-c4ccccc4)n(C)c3=O)c2=O)c2scc(C(O)=O)c2n1

BDBM545704

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc([C@@H]4C[C@H](O)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1 |r,wD:22.22,24.25,(9.61,1.93,;8.28,1.15,;6.94,1.93,;5.61,1.15,;4.28,1.93,;4.28,3.47,;2.94,4.23,;2.94,5.78,;1.61,3.47,;1.61,1.93,;2.94,1.15,;2.94,-.38,;1.61,-1.15,;1.61,-2.69,;.28,-3.47,;.28,-5,;1.61,-5.78,;-1.06,-5.78,;-2.39,-5,;-3.72,-5.78,;-5.06,-5,;-5.06,-3.47,;-6.39,-2.69,;-7.88,-3.09,;-8.28,-1.61,;-9.61,-.84,;-6.79,-1.21,;-3.72,-2.69,;-3.72,-1.15,;-3.72,.38,;-2.39,-3.47,;-1.06,-2.69,;-1.06,-1.15,;5.61,-.38,;4.47,-1.42,;5.09,-2.82,;6.62,-2.66,;7.65,-3.81,;7.18,-5.27,;9.16,-3.49,;6.94,-1.15,;8.28,-.38,)|

BDBM545705

COC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cnc(N(C)C3CCN(CC(F)(F)F)CC3)c(C#N)c2c1=O

BDBM545706

CNC1CN(C1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545707

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(OCC(F)F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545708

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(Cl)nc(C4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545709

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(nc(C4CC4)c(C#N)c3c2=O)N(C)C)c2scc(C(O)=O)c2n1

BDBM545710

CN(C)CCc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545711

Cc1sc2c(cc(C)nc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(Cl)c(N3CCN(CC3)C(C)(C)C)c(C#N)c2c1=O

BDBM545712

CN1[C@H]2C[C@@H]1CN(C2)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N |r,THB:0:1:6.7.5:3|

BDBM545713

CN1C[C@@H]2C[C@H](C1)N2c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N |r,THB:8:7:6.1.2:4|

BDBM545714

Cc1nc2cnc(C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cc(CC(O)=O)n2nccc2c1

BDBM545715

CC1N=C2C(=O)C(F)=C(C(C#N)=C2C(=O)N1CCOc1ccc(Cl)cc1-c1cc(C)nc2c(C(O)=O)c(C)sc12)c1ccccc1 |c:7,11,t:2|

BDBM545716

COC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(N3CCN(CC3)C3CC3)c(C#N)c2c1=O)C(F)(F)F

BDBM545717

CN1CCN(CC1C(F)(F)F)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545718

COc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c(C#N)c1N1CCN(C)CC1

BDBM545719

CN1CCN(CC1)c1cc2c(cc1S(C)(=O)=O)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

BDBM545720

CN1CCN(CC1)c1cc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(C(O)=O)c(C)sc13)c2=O

BDBM545721

CN1CCN(CC1)c1cc2nc(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(C)nc2cc1C(F)(F)F

BDBM545722

CN1CCN(CC1)c1c(cc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545723

CN1CCN(CC1)c1c(cc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545724

CN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccc(F)c3c(csc13)C(O)=O)c2=O

BDBM545725

CCc1cc(-c2cc(F)c(F)cc2OCCn2c(C)nc3cc(c(N4CCN(C)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545726

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc([C@H]4[C@H]5CN(C)C[C@@H]45)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1 |r|

BDBM545727

CN1CCN(CC1)c1nc(-c2ccccc2)c2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545728

CN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccc(C)c3c(csc13)C(O)=O)c2=O

BDBM545729

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CCN(C)C5CC45)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545730

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CCNC5CC45)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545731

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc(c3)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545732

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc(c3)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545733

CCc1cc(cc(n1)C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(N3CCN(C)CC3)c(C#N)c2c1=O)C(F)(F)F

BDBM545734

COc1cc(cc(n1)C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(N3CCN(C)CC3)c(C#N)c2c1=O)C(F)(F)F

BDBM545735

CN(C)c1cc(cc(n1)C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(N3CCN(C)CC3)c(C#N)c2c1=O)C(F)(F)F

BDBM545736

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc(C(O)=O)c3C)c(=O)c2c1C#N)C(F)(F)F

BDBM545737

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4ccc(C)c(O)c4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545738

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)-c3nn[nH]n3)c(=O)c2c1C#N)C(F)(F)F

BDBM545739

CN(CCF)[C@H]1CC[C@@H](CC1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:8.11,wD:5.4,(-4.44,3.85,;-5.78,3.08,;-7.11,3.85,;-7.11,5.39,;-8.44,6.16,;-5.78,1.54,;-7.11,.77,;-7.11,-.77,;-5.78,-1.54,;-4.44,-.77,;-4.44,.77,;-5.78,-3.08,;-7.11,-3.85,;-4.44,-3.85,;-4.44,-5.39,;-3.11,-6.16,;-1.78,-5.39,;-.44,-6.16,;.89,-5.39,;2.23,-6.16,;.89,-3.85,;2.23,-3.08,;2.23,-1.54,;2.23,,;2.23,1.54,;.89,2.31,;.89,3.85,;2.23,4.62,;2.23,6.16,;3.56,3.85,;3.56,2.31,;4.89,1.54,;6.23,2.31,;7.56,1.54,;7.56,,;6.23,-.77,;5.91,-2.28,;4.38,-2.44,;3.75,-1.03,;4.89,,;6.94,-3.42,;8.44,-3.1,;6.46,-4.89,;-.44,-3.08,;-.44,-1.54,;-1.78,-3.85,;-3.11,-3.08,;-3.11,-1.54,;-3.11,,)|

BDBM545740

CN1CCN(CC1)c1cc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545741

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CCN(C)CC4=O)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545742

COC1CCN(C1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545743

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N4CCC(O)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545744

Cc1sc2c(cc(C)nc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cnc(N3CCC(O)C3)c(C#N)c2c1=O

BDBM545745

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(CF)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545746

COCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CCN(C)CC4)c(C#N)c3c2=O)C(F)(F)F)c2sc(C)c(C(O)=O)c2c1

BDBM545747

Cc1nc2cc(c(N3CCN(CC(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545748

CN1CCN(CC1)c1c(C#N)c2c(cc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c2=O)cc1C(F)(F)F

BDBM545749

Cc1nc2cc(c(N3CCN(CC3)C3COC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545750

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CCN(CC4)C4COC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545751

COCCN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545752

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4cc(sc34)C#C)c(=O)c2c1C#N)C(F)(F)F

BDBM545753

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4cc(sc34)C#N)c(=O)c2c1C#N)C(F)(F)F

BDBM545754

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4cc(Cl)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545755

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(Cl)csc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545756

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4cc(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545757

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(C)csc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545758

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ncnc4ccsc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545759

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4cnsc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545760

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(C)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545761

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(CF)nc4ccsc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545762

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C#N)c(=O)c2c1C#N)C(F)(F)F

BDBM545763

CN(C)CCc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4ccsc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545764

CN1CCN(Cc2c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4ccnc5ccsc45)c(=O)c3c2C#N)C(F)(F)F)CC1

BDBM545765

CN1CCN(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4ccsc34)c(=O)c2c1C#N

BDBM545766

Cc1nc2cnc(N3CCC(O)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2ccsc12

BDBM545767

CN(C)CC#Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545768

Cc1nc2cc(c(C#CCN)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545769

CN1CCN(CC1CO)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545770

CN1CCN(CC1C(F)(F)F)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545771

CN1CCC(C1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545772

CN1CCC(F)(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545773

CN1CC2(C1)CN(C2)c1nc(C)c2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545774

Cc1nc2c(C)nc(N3CC4(CNC4)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545775

CN(C)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1-c1cc(F)cnc1C |(-7.11,-6.93,;-5.78,-6.16,;-4.44,-6.93,;-5.78,-4.62,;-4.44,-3.85,;-3.11,-4.62,;-1.78,-3.85,;-.44,-4.62,;.89,-3.85,;2.23,-4.62,;.89,-2.31,;2.23,-1.54,;2.23,,;3.56,.77,;3.56,2.31,;2.23,3.08,;2.23,4.62,;3.56,5.39,;3.56,6.93,;4.89,4.62,;4.89,3.08,;6.23,2.31,;7.56,3.08,;8.89,2.31,;8.89,.77,;7.56,,;7.24,-1.51,;5.71,-1.67,;5.08,-.26,;6.23,.77,;8.27,-2.65,;7.8,-4.12,;9.78,-2.33,;-.44,-1.54,;-.44,,;-1.78,-2.31,;-3.11,-1.54,;-3.11,,;-3.11,1.54,;-4.44,-2.31,;-5.78,-1.54,;-7.11,-2.31,;-8.44,-1.54,;-9.78,-2.31,;-8.44,,;-7.11,.77,;-5.78,,;-4.44,.77,)|

BDBM545776

COc1ccc(cc1)-c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cnc(N3CCN(C)CC3)c(C#N)c2c1=O

BDBM545777

CN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCSc1ccc(Cl)cc1-c1ccnc3c(csc13)C(O)=O)c2=O

BDBM545778

CN1CCN(C(=O)C1)c1c(cc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545779

CN1CCN(CC1)c1c(cc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545780

CN1CCN(C(=O)C1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545781

CN1CCN(CC1)c1nc(C)c2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545782

Cc1nc2c(C)nc(N3CCN(CC(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545783

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CC4CCN(C)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545784

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CC4CCNCC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545785

Cc1nc2cc(CN3CC(F)(F)C3)c(OC(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545786

CN(CCF)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1OC(F)F

BDBM545787

Cc1nc2cnc(C3CCC(F)(F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545788

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3ccc(N4CCC(O)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545789

CN(C1CCN(CC(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(N)=O)c(=O)c2c1C#N

BDBM545790

CN1CCN(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N

BDBM545791

CN1CC(Cc2c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4ccnc5c(C(O)=O)c(C)sc45)c(=O)c3c2C#N)C(F)(F)F)C1

BDBM545792

CN(C)Cc1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(C(O)=O)c(C)sc34)c(=O)c2c(C#N)c1-c1cc(F)cnc1C |(-7.11,-6.93,;-5.78,-6.16,;-4.44,-6.93,;-5.78,-4.62,;-4.44,-3.85,;-3.11,-4.62,;-1.78,-3.85,;-.44,-4.62,;.89,-3.85,;2.23,-4.62,;.89,-2.31,;2.23,-1.54,;2.23,,;3.56,.77,;3.56,2.31,;2.23,3.08,;2.23,4.62,;3.56,5.39,;3.56,6.93,;4.89,4.62,;4.89,3.08,;6.23,2.31,;7.56,3.08,;8.89,2.31,;8.89,.77,;7.56,,;7.24,-1.51,;8.27,-2.65,;7.8,-4.12,;9.78,-2.33,;5.71,-1.67,;4.94,-3,;5.08,-.26,;6.23,.77,;-.44,-1.54,;-.44,,;-1.78,-2.31,;-3.11,-1.54,;-3.11,,;-3.11,1.54,;-4.44,-2.31,;-5.78,-1.54,;-7.11,-2.31,;-8.44,-1.54,;-9.78,-2.31,;-8.44,,;-7.11,.77,;-5.78,,;-4.44,.77,)|

BDBM545794

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccc(F)c4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545795

Cc1nc2cc(c(CCN3CC(F)(F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545796

CN(CCc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F)CC(F)F

BDBM545798

Cc1nc2cc(c(nc2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)N1CCN(CC(F)F)CC1)C(F)(F)F

BDBM545799

Cc1nc2cc(c(N3CCN(CC3)C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545800

Cc1nc2cc(c(N3CCN(CC3)C3CC(F)(F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545801

Cc1nc2cc(c(N3CCN(CCC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM545802

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)S(C)(=O)=O

BDBM545803

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)S(C)(=O)=O

BDBM545804

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)S(C)(=O)=O

BDBM545805

CN1CCN(CC1)c1nc(C)c2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N

BDBM545806

CN(C)CCc1c(cc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545807

CN1CCN(CC1)c1cc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1ccnc3c(csc13)C(=O)NS(C)(=O)=O)c2=O

BDBM545809

CN1CCN(C2CC12)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545811

Cc1nc2cnc(N3CCN(CC(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545812

Cc1nc2cnc(N3CCN(CC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545813

CN1CCN(CC1C(F)F)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545814

Cc1nc2cnc(N3CCN(CC3)C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545815

Cc1nc2cnc(N3CCN(CC3)C3CC(F)(F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545816

Cc1nc2cnc(N3CCN(CCC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545817

Cc1nc2cnc(N3CCN(CC3)C(C)(C)C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545818

Cc1nc2cnc(N3CCN(CC3)C3(CC3)C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545819

Cc1nc2cnc(N3CCN4CC(F)(F)CC4C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545820

CC(C(F)F)N1CCN(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545821

Cc1nc2cnc(N3CCN(CC3)C(C)(C)C)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545822

Cc1nc2cnc(N3CC4(CN(C4)C4CC4)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545823

CC(N1CCN(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM545824

Cc1nc2cnc(N3CCN(CC3)C(C)(C)C(F)(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545825

Cc1nc2cnc(N3CCN(CC(C)(C)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545826

CN(C1CCN(CC(F)F)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545827

CN(C1CCN(CC1)C1CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545828

CN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545829

Cc1nc2cnc(N3CCN(CC3)C3COC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545830

Cc1nc2cnc(N3CC4(CN(C4)C4COC4)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545831

CN(C1CCN(C)C1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545832

CN(C)c1cc(C)cc(c1)-c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545833

CN(C)Cc1ccc(cn1)-c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545834

CN(CCF)CC#Cc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545835

CN(CC#Cc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)CC(F)(F)F

BDBM545836

CN(CCF)C\C=C\c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545837

CN(C)C1(CC1)C#Cc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545838

CN1CCOC(C1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545839

CN(C)CCSc1cncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c12

BDBM545840

CN1CC(=C(C1)C(C)(C)C)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |c:3|

BDBM545841

Cc1nc2cnc(N3CCN(CCF)C(C)(C)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545842

CN1CCN(CC1C(F)(F)F)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545843

CC1CN(C)CCN1c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545844

Cc1nc2cnc(N3CCN(CC3)C3(CF)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545845

CN1CCN(CC11CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545846

Cc1nc2cnc(N3CCN(CCF)C4(CC4)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545847

Cc1nc2cnc(N3CCN(CCS(C)(=O)=O)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545848

Cc1nc2cnc(N3CC(C3)N3CCC(F)(F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545849

Cc1nc2cnc(N3CC(C3)N3CC(F)(F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545850

CN1CCN(CC1CC#N)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545851

Cc1nc2cnc(N3CCN(CC3)C(C)(C)CC#N)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545852

Cc1nc2cnc(C#CC3CCCN3C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545853

CN(CCF)CCCc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545854

CN(CC#Cc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C1(C)CC1

BDBM545855

CN1CCN(C2CC12)c1ncc2nc(C)n(C\C=C\c3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545856

Cc1nc2cnc(N3CCN4CCC3C4)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545857

Cc1nc2cnc(SC3CCN(CC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545858

C[C@H]1CN(C[C@@H](C)N1CC(F)F)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM545859

CN1CCN(CC11COC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545860

Cc1nc2cnc(N3CCN(CCF)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545864

Cc1nc2cnc(N3CCN(CC(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545865

Cc1nc2cnc(N3CC4CC3CN4CC(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545866

Cc1nc2cnc(N3CCN(CC(F)C(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545867

Cc1nc2cnc(N3CCN(CC(C(F)(F)F)C(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545868

CN(C1CCN(CCC(F)(F)F)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545869

Cc1nc2cnc(N3CCN(CC3)C3(CC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545870

Cc1nc2cnc(N3CCN(CC(F)(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O

BDBM545871

CN1C2(CC2)CN(CC11CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545872

Cc1nc2cnc(N3CCN(CC3)C(CF)CF)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545873

Cc1nc2cnc(N3CCN(CC3)C3(C)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545874

Cc1nc2cnc(N3CCN(CC3)C3(CC3)C(F)F)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545875

Cc1nc2cnc(N3CCN(CC3)C(C)(C)CC#N)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545876

Cc1nc2cnc(N3CCN(CC3)C3(CC3)C#N)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545877

Cc1nc2cnc(N3CC4(CN(C4)C4CCCC4)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545878

CN(C1CCN(CC2CC2)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545879

Cc1nc2cnc(N3CC4(CCC4C4CC4)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545880

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc(c1)C(=O)NS(C)(=O)=O)C(F)(F)F

BDBM545881

Cc1nc2c(F)ccc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545882

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cc(CCN)nc2c(csc12)C(O)=O)C(F)(F)F

BDBM545883

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)-c1cc(O)no1)C(F)(F)F

BDBM545884

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CN4CCSCC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545885

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CN4CCS(=O)(=O)CC4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545886

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(ncc(C#N)c3c2=O)-c2ccccc2)c2scc(C(O)=O)c2n1

BDBM545887

CN(C)Cc1c(C)cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545888

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ncccc4C)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(9.34,2.7,;8,1.93,;6.67,2.7,;5.33,1.93,;4,2.7,;4,4.24,;2.67,5,;2.67,6.54,;1.33,4.24,;1.33,2.7,;2.67,1.93,;2.67,.38,;1.33,-.38,;1.33,-1.93,;,-2.69,;,-4.23,;1.33,-5,;-1.33,-5,;-2.67,-4.23,;-4,-5,;-5.33,-4.23,;-5.33,-2.69,;-6.67,-1.93,;-8,-2.69,;-9.34,-1.93,;-9.34,-.38,;-8,.38,;-6.67,-.38,;-5.33,.38,;-4,-1.93,;-4,-.38,;-4,1.15,;-2.67,-2.69,;-1.33,-1.93,;-1.33,-.38,;-6.67,-5,;-6.67,-6.54,;-8,-5.78,;-8,-4.23,;5.33,.39,;4.19,-.65,;4.82,-2.05,;6.35,-1.89,;7.38,-3.04,;8.88,-2.72,;6.9,-4.5,;6.67,-.38,;8,.39,)|

BDBM545889

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccc(F)cn4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545890

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(-c4ccccc4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545891

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cnc(C)c(F)c4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545892

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4cnc(Cl)cc4F)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1 |(10,2.69,;8.67,1.93,;7.34,2.7,;6,1.93,;4.67,2.69,;4.67,4.23,;3.33,5,;3.33,6.54,;2,4.23,;2,2.69,;3.33,1.93,;3.33,.38,;2,-.38,;2,-1.93,;.67,-2.69,;.67,-4.23,;2,-5,;-.67,-5,;-2,-4.23,;-3.33,-5,;-4.67,-4.23,;-4.67,-2.69,;-6,-1.93,;-7.34,-2.69,;-8.67,-1.93,;-8.67,-.38,;-10,.38,;-7.34,.38,;-6,-.38,;-4.67,.38,;-3.33,-1.93,;-3.33,-.38,;-3.33,1.15,;-2,-2.69,;-.67,-1.93,;-.67,-.38,;-6,-5,;-7.34,-4.23,;-6,-6.54,;-7.34,-5.78,;6,.38,;4.86,-.65,;5.48,-2.05,;7.02,-1.89,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;7.34,-.38,;8.67,.38,)|

BDBM545893

Cc1cc(cc(C)n1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)F

BDBM545894

Cc1cc(ccn1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)F

BDBM545895

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(C(F)F)c(-c4cncc(F)c4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM545896

Cc1cc(F)c(cn1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-10,.38,;-8.67,-.38,;-7.34,.38,;-6,-.38,;-4.67,.38,;-6,-1.93,;-7.34,-2.69,;-8.67,-1.93,;-4.67,-2.69,;-4.67,-4.23,;-3.33,-5,;-2,-4.23,;-.67,-5,;.67,-4.23,;2,-5,;.67,-2.69,;2,-1.93,;2,-.38,;3.33,.38,;3.33,1.93,;2,2.69,;2,4.23,;3.33,5,;3.33,6.54,;4.67,4.23,;4.67,2.69,;6,1.93,;7.34,2.7,;8.67,1.93,;10,2.69,;8.67,.38,;7.34,-.38,;7.02,-1.89,;5.48,-2.05,;4.86,-.65,;6,.38,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;-.67,-1.93,;-.67,-.38,;-2,-2.69,;-3.33,-1.93,;-3.33,-.38,;-3.33,1.15,;-6,-5,;-7.34,-4.23,;-6,-6.54,;-7.34,-5.78,)|

BDBM545897

Cc1cc(O)c(cn1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F |(-10,.38,;-8.67,-.38,;-7.34,.38,;-6,-.38,;-4.67,.38,;-6,-1.93,;-7.34,-2.69,;-8.67,-1.93,;-4.67,-2.69,;-4.67,-4.23,;-3.33,-5,;-2,-4.23,;-.67,-5,;.67,-4.23,;2,-5,;.67,-2.69,;2,-1.93,;2,-.38,;3.33,.38,;3.33,1.93,;2,2.69,;2,4.23,;3.33,5,;3.33,6.54,;4.67,4.23,;4.67,2.69,;6,1.93,;7.34,2.7,;8.67,1.93,;10,2.69,;8.67,.38,;7.34,-.38,;7.02,-1.89,;5.48,-2.05,;4.86,-.65,;6,.38,;8.05,-3.04,;7.57,-4.5,;9.55,-2.72,;-.67,-1.93,;-.67,-.38,;-2,-2.69,;-3.33,-1.93,;-3.33,-.38,;-3.33,1.15,;-6,-5,;-7.34,-4.23,;-6,-6.54,;-7.34,-5.78,)|

BDBM545898

COC(=O)c1csc2c(cc(C)nc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(N3CCN(C)CC3)c(C#N)c2c1=O)C(F)(F)F

BDBM545899

Cc1sc2c(cc(C)nc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(OCCN3CCNCC3)c(C#N)c2c1=O)C(F)(F)F

BDBM545900

Cc1sc2c(cc(C)nc2c1C(O)=O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(N3CCN(CCO)CC3)c(C#N)c2c1=O)C(F)(F)F

BDBM545901

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(CC4CN(C)C4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM545902

Cc1nc2c(ncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)N1CCN(CCOC(F)(F)F)CC1

BDBM545903

Cc1nc2cnc(N3CCN(CCOC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545904

Cc1nc2c(ncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)N1CCN(CC1)C1(COC1)C(F)F

BDBM545906

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N

BDBM545907

Cc1nc2cnc(N3CCN(CC3)C(C)(C)CCC(F)(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545908

Cc1nc2cnc(N3CCN(CC3)C3(CCC(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545909

CN(CCF)C\C=C\c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545910

CN([C@@H]1[C@H]2CN(CC(F)F)C[C@@H]12)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM545911

COC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cnc(N3CCN(CC(F)F)CC3)c(C#N)c2c1=O

BDBM545913

CN([C@@H]1C[C@@H]2CC[C@H](C1)N2CC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(C)=O)c(=O)c2c1C#N |r,THB:10:9:2.3.8:6.5|

BDBM545914

CN([C@H]1[C@H]2CN(CC(F)F)C[C@@H]12)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM545915

Cc1nc2cnc(N3CCC4(CN(CC(F)F)C4)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(=O)(=O)C1COC1

BDBM545916

Cc1nc2cnc(N3CCC4(CN(CC(F)F)C4)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(=O)(=O)c1cccnc1

BDBM545917

Cc1nc2cnc(N3CCC4(CN(CC(F)F)C4)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O

BDBM545918

Cc1nc2cnc(N3CCC4(CN(CC(C)(F)F)C4)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(=O)(=O)C1COC1

BDBM545919

Cc1nc2cnc(N3CCC4(CN(CC(C)(F)F)C4)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(=O)(=O)c1cccnc1

BDBM545920

CN(c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)C1(C)CCN(CC(F)F)CC1

BDBM545921

CN(CC(F)F)C1(C)CCN(CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545922

CN1CCC(C)(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545923

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545924

CN1CCC(=CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F |c:4|

BDBM545925

CN1CCN(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N

BDBM545926

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(ncc(C#N)c3c2=O)C2COC2)c2scc(C(O)=O)c2n1

BDBM545927

CN1CC2(C1)CN(C2)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(C(O)=O)c(C)sc34)c(=O)c2c1C#N)C(F)(F)F

BDBM545928

CN1CC(F)(C1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545931

CC(CF)N1CCN(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545932

Cc1nc2cnc(N3CCN(CC3)C3(CCF)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545933

Cc1nc2cnc(N3CCC(CC3)C3(CF)CC(F)(F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545934

CN(CC(F)(F)F)C1CCC(C1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545935

CN(C1CCN(CC1)C1(CF)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545936

CN(C1CCN(CC1)C(C)(C)CF)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545937

CN(C1CCN(CC1)C1(CC1)C(F)F)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545938

CN(C1CCN(CC1)C(C)(C)C(F)F)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545939

CN(C1CCN(CC1)C(CF)CF)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545940

CCN(C1CCN(CC(F)F)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545941

Cc1nc2cnc(N3CC4(C3)CN(C4)C3(C)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545942

Cc1nc2cnc(N3CC4(C3)CN(C4)C3(C)CC(F)(F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545943

Cc1nc2cnc(N3CC4(CN(C4)C4CC4(C)C)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545944

Cc1nc2cnc(N3CC4(CN(C4)C4CCC4)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545945

Cc1nc2cnc(N3CCN(C4CC4)C(C3)C(F)(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545946

Cc1nc2cnc(N3CCN(C4CC4)C(C3)C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545947

Cc1nc2cnc(C(=O)C3CCN(CC(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545948

CN(C1CCN(CC(F)(F)Cl)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545949

CC(CF)N1CCN(CC1)c1ncc2cc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545950

Cc1cc2cnc(N3CCN(CC3)C3(C)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545951

Cc1cc2cnc(N3CCN(CC3)C3(CF)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545952

Cc1cc2cnc(N3CCN(CC3)C3(CCF)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545953

Cc1cc2cnc(N3CCN(CC3)C3CC3(C)C)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545954

Cc1cc2cnc(N3CCN(CC3)C(CF)CF)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545955

Cc1cc2cnc(N3CCN(CC(C)(F)CF)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545956

Cc1cc2cnc(N3CCN(CC(=C)CF)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545957

Cc1cc2cnc(N3CCN(CC4(C)CC4)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545958

Cc1cc2cnc(N3CCN(CC3)C(C)(C)CF)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545959

Cc1cc2cnc(N3CCN(CC(C)(C)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545960

Cc1cc2cnc(N3CCN(CC3)C(C)(C)CCF)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545961

Cc1cc2cnc(N3CCN(CC3)C(C)(C)C(F)F)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545962

Cc1cc2cnc(N3CCN(CCC(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545963

Cc1nc2cnc(N3CCN(CCCF)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545964

Cc1nc2cnc(N3CCN(CCCC(F)(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545965

CN1CCN(CC1CF)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545966

CN1CCN(CC1COC(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545967

Cc1nc2cnc(C3=CCN(CC3)C3CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |t:7|

BDBM545968

Cc1nc2cnc(C3=CCN(CCF)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |t:7|

BDBM545969

Cc1nc2cnc(C3=CCN(CC(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |t:7|

BDBM545970

Cc1nc2cnc(N3CCN(CCOC(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545971

COCC1(CC1)N1CCN(CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545972

CC(C(F)F)N1CCN(CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545973

Cc1nc2cnc(N3CCC(CC3)N3CC(F)(F)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545974

CN(CC#Cc1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)CC(F)(F)F

BDBM545975

CCC(F)(CC)CN1CCN(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545976

Cc1nc2cnc(N3CCN(CC4(F)CC4)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545977

Cc1nc2cnc(N3CCN(CC4(CC4)C(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545978

Cc1nc2cnc(N3CCN(CC(C)(C)C(F)(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545979

Cc1nc2cnc(N3CCN(CC3)C3C(C)(C)C3(C)C)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545980

Cc1nc2cnc(N3CCN(CC(F)(F)Cl)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545981

Cc1nc2cnc(N3CC4(CN(C4)C4CC(F)(F)C4)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545982

Cc1nc2cnc(N3CC4(CN(C4)C4C(C)(C)C4(C)C)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545983

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM545984

Cc1nc2cnc(N3C[C@@H]4CN(CC(F)F)C[C@@H]4C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |r|

BDBM545985

Cc1nc2cnc(OC3CCN(CCF)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545986

Cc1nc2cnc(C3CCC(F)(F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545987

Cc1nc2cnc(C3=CCC(F)(F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |t:7|

BDBM545988

Cc1nc2cnc(N3CCN(CC3)C(C)(C)CF)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O

BDBM545989

Cc1nc2cnc(CC3CCN(CC(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545990

CN(CCc1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)CC(F)F

BDBM545991

Cc1nc2cnc(N3CCN(CCC(F)(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O

BDBM545992

Cc1nc2cnc(N3CCN(CC(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O

BDBM545993

Cc1nc2cnc(N3CCN(CCF)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O

BDBM545994

Cc1nc2cnc(N3CCN(CC3)C3CCC3(F)F)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545995

Cc1nc2cnc(N3CCC4(CCN4CC(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545996

CN(CCN(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)CC(F)(F)F

BDBM545997

CN(CCc1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)CC(F)F

BDBM545998

Cc1nc2cnc(N3CCN(CC3)C3(C)CC(F)(F)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM545999

CN(C1CCN(CC1)C1(CC1)C#N)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546000

CN(C1CCN(C)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546001

CN(C1CCN(C2CC2)C2(CC2)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546002

CN(CCCN(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)CC(F)(F)F

BDBM546003

CN(C)C\C=C\c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546004

Cc1nc2cnc(N3CCC33CN(CC(F)F)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546005

Cc1nc2cnc(N3CCC33CCN(CC(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546006

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N

BDBM546007

CCC(F)(F)CN1CCC(CC1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546008

CN(C1CCN(CCOC(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546009

CN(C1CCN(CC1)C1(COC(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546011

CN(C1CCN(CC1)C(C)(C)C(C)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546012

CN(C1CCN(CC1)C(C)(C)C(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546013

CC(CF)N1CCC(CC1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546014

Cc1nc2cnc(N3CCN(CCCOC(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546015

Cc1nc2cnc(N3CCN(CC3)C3(COC(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546016

Cc1nc2cnc(N3CCN(CC3)[C@@H]3C[C@@H](C3)OC(F)F)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |r,wU:13.13,15.18,(5.17,-6.16,;3.84,-5.39,;2.5,-6.16,;1.17,-5.39,;-.17,-6.16,;-1.5,-5.39,;-1.5,-3.85,;-2.83,-3.08,;-2.83,-1.54,;-4.17,-.77,;-5.5,-1.54,;-5.5,-3.08,;-4.17,-3.85,;-6.83,-.77,;-7.23,.72,;-8.72,.32,;-8.32,-1.17,;-10.05,1.09,;-10.05,2.63,;-11.39,3.4,;-8.72,3.4,;-.17,-3.08,;-.17,-1.54,;-.17,,;1.17,-3.85,;2.5,-3.08,;2.5,-1.54,;3.84,-3.85,;5.17,-3.08,;5.17,-1.54,;5.17,,;5.17,1.54,;3.84,2.31,;3.84,3.85,;5.17,4.62,;5.17,6.16,;6.5,3.85,;6.5,2.31,;7.84,1.54,;9.17,2.31,;10.5,1.54,;10.5,,;9.17,-.77,;8.85,-2.28,;7.32,-2.44,;6.69,-1.03,;7.84,,;9.88,-3.42,;9.4,-4.89,;11.39,-3.1,)|

BDBM546017

Cc1nc2cnc(N3CC4(CN(C4)C4CCC4)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O

BDBM546018

CN(C1CCN(CCOC(F)F)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546019

CN(C1CCN(CC1)C(C)(C)C(F)(F)F)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546020

CN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546021

Cc1nc2cnc(N3CCN(CC(C)(C)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O

BDBM546022

CC(C(F)F)N1CCC(CC1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546023

CN(C1CCN(CC(C)=O)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546024

CN(C1CCN(CCC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546025

CN(C1CCN(CCCF)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546026

CN(C1CCN(CC1)C1(CC1)C(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546027

CN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546028

CN(C1CCN(CC1)C1(C)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546029

Cc1nc2cnc(N3CC4(CCN4C4CC4)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546030

Cc1nc2cnc(N3CCC(CC3)[C@@H]3C[C@H]3C(F)(F)F)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |r|

BDBM546031

CN(C1CC1)C1CCN(CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546032

CN(C1CCOCC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546033

CN(C1CCN(CC1)C1(CF)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546034

CN(C1CCN(CC1)C1(CC1)C(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546035

CN([C@H]1C[C@H]2CN(CC(F)F)C[C@H]2C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM546036

CN(CCF)[C@H]1C[C@@H](C1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:7.9,wD:5.4,(-4.44,2.95,;-5.78,2.18,;-7.11,2.95,;-7.11,4.49,;-8.44,5.26,;-5.78,.64,;-6.87,-.45,;-5.78,-1.54,;-4.69,-.45,;-5.78,-3.08,;-7.11,-3.85,;-4.44,-3.85,;-4.44,-5.39,;-3.11,-6.16,;-1.78,-5.39,;-.44,-6.16,;.89,-5.39,;2.23,-6.16,;.89,-3.85,;2.23,-3.08,;2.23,-1.54,;2.23,,;2.23,1.54,;.89,2.31,;.89,3.85,;2.23,4.62,;2.23,6.16,;3.56,3.85,;3.56,2.31,;4.89,1.54,;6.23,2.31,;7.56,1.54,;7.56,,;6.23,-.77,;5.91,-2.28,;4.38,-2.44,;3.75,-1.03,;4.89,,;6.94,-3.42,;6.46,-4.89,;8.44,-3.1,;-.44,-3.08,;-.44,-1.54,;-1.78,-3.85,;-3.11,-3.08,;-3.11,-1.54,;-3.11,,)|

BDBM546037

CN(CCF)[C@H]1CC[C@H](CC1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:8.11,5.4,(-4.44,3.85,;-5.78,3.08,;-7.11,3.85,;-7.11,5.39,;-8.44,6.16,;-5.78,1.54,;-4.44,.77,;-4.44,-.77,;-5.78,-1.54,;-7.11,-.77,;-7.11,.77,;-5.78,-3.08,;-7.11,-3.85,;-4.44,-3.85,;-4.44,-5.39,;-3.11,-6.16,;-1.78,-5.39,;-.44,-6.16,;.89,-5.39,;2.23,-6.16,;.89,-3.85,;2.23,-3.08,;2.23,-1.54,;2.23,,;2.23,1.54,;.89,2.31,;.89,3.85,;2.23,4.62,;2.23,6.16,;3.56,3.85,;3.56,2.31,;4.89,1.54,;6.23,2.31,;7.56,1.54,;7.56,,;6.23,-.77,;5.91,-2.28,;4.38,-2.44,;3.75,-1.03,;4.89,,;6.94,-3.42,;8.44,-3.1,;6.46,-4.89,;-.44,-3.08,;-.44,-1.54,;-1.78,-3.85,;-3.11,-3.08,;-3.11,-1.54,;-3.11,,)|

BDBM546038

CN(C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546039

CCN(C1CCN(CC(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546040

CN(C1CCN(CC(F)(F)c2ccn(C)n2)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546041

CN(C1CCN(CC1)C(C(F)F)c1ccn(C)n1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546042

CC(C)S(=O)(=O)NC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cnc(N(C)C3CCN(CC(F)(F)F)CC3)c(C#N)c2c1=O

BDBM546043

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC(F)F)c(=O)c2c1C#N

BDBM546044

CN(C1CCCN(CC(F)F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546045

CN(CC1CCN(CC(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546046

CN(CC1CN(CC(F)F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546047

Cc1nc2cnc(OC3CCN(CC3)C3CC(F)(F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546048

Cc1nc2cnc(N3CCC[C@@H]4CN(CC(F)F)CC[C@H]34)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |r|

BDBM546049

CN(C1C[C@@H]2C[C@H]1CN2CC(C)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM546050

CN(C)S(=O)(=O)NC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cnc(N(C)C3CCN(CC(F)(F)F)CC3)c(C#N)c2c1=O

BDBM546051

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3CC3)c(=O)c2c1C#N

BDBM546052

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccc3)c(=O)c2c1C#N

BDBM546053

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccc3C)c(=O)c2c1C#N

BDBM546054

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccc(F)cc3F)c(=O)c2c1C#N

BDBM546056

Cc1nc2cnc(N3CCC(CC3)N(CC(F)F)C3COC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546057

Cc1nc2cnc(N(C3CCN(CC(F)(F)F)CC3)c3cncs3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546058

CN(C1CCN(CC(F)(F)c2ccccc2)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546059

Cc1nc2cnc(N3CC[C@H]4CN(CC(F)F)CC[C@@H]34)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |r|

BDBM546060

CC(C#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)n1c(C)nc2cnc(N(C)C3CCN(CC(F)F)CC3)c(C#N)c2c1=O

BDBM546061

Cc1nc2cnc(-c3cccc4CN(CC(F)F)CCc34)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546062

CN(CC(F)F)Cc1cccc(c1)-c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546063

CN(C1CCN(CC(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NO)c(=O)c2c1C#N

BDBM546064

CN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N

BDBM546065

CN(C1CCN(CC(C)(F)F)CC1)c1nc(C)c2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546066

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546067

Cc1nc2cnc(N3CCC(CC3)N3CC(F)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546069

CN(C1CCN(CC(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N

BDBM546071

CN(c1ccncc1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546072

Cc1nc2cc(c(N3CC4(CN(C4)C4CC4)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM546073

Cc1nc2cnc(C3CCCN(CC(F)F)C3)c(C#N)c2c(=O)n1CCCc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546074

Cc1nc2cnc(c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)C1CCN(CC(F)F)CC1

BDBM546075

CN(CC(F)F)C1CCC(=CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |c:9|

BDBM546076

Cc1nc2cnc(C3CCCN(CC(F)F)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546077

CN(C1[C@H]2CC[C@@H]1CN(CC(C)(F)F)C2)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM546078

CN([C@H]1[C@H]2C[C@@H]1CN(CC(C)(F)F)C2)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM546079

CN([C@@H]1[C@H]2C[C@@H]1CN(CC(C)(F)F)C2)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM546080

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N

BDBM546081

CC(CO)N(CC(F)F)[C@H]1CC[C@@H](CC1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:9.8,wD:12.15,(-8.44,3.08,;-7.11,3.85,;-7.11,5.39,;-8.44,6.16,;-5.78,3.08,;-4.44,3.85,;-4.44,5.39,;-3.11,6.16,;-5.78,6.16,;-5.78,1.54,;-4.44,.77,;-4.44,-.77,;-5.78,-1.54,;-7.11,-.77,;-7.11,.77,;-5.78,-3.08,;-7.11,-3.85,;-4.44,-3.85,;-4.44,-5.39,;-3.11,-6.16,;-1.78,-5.39,;-.44,-6.16,;.89,-5.39,;2.23,-6.16,;.89,-3.85,;2.23,-3.08,;2.23,-1.54,;2.23,,;2.23,1.54,;.89,2.31,;.89,3.85,;2.23,4.62,;2.23,6.16,;3.56,3.85,;3.56,2.31,;4.89,1.54,;6.23,2.31,;7.56,1.54,;7.56,,;6.23,-.77,;5.91,-2.28,;4.38,-2.44,;3.75,-1.03,;4.89,,;6.94,-3.42,;6.46,-4.89,;8.44,-3.1,;-.44,-3.08,;-.44,-1.54,;-1.78,-3.85,;-3.11,-3.08,;-3.11,-1.54,;-3.11,,)|

BDBM546082

CN(CC(F)F)[C@@H]1CC[C@H](C1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM546083

CN(C1CCN(CC(F)(F)C2CC(F)(F)C2)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546084

CN(C[C@H]1CC[C@@H](CC1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)CC(C)(F)F |r,wU:6.9,wD:3.2,(-7.67,2.31,;-6.34,3.08,;-5.01,2.31,;-5.01,.77,;-6.34,,;-6.34,-1.54,;-5.01,-2.31,;-3.67,-1.54,;-3.67,,;-5.01,-3.85,;-6.34,-4.62,;-3.67,-4.62,;-3.67,-6.16,;-2.34,-6.93,;-1.01,-6.16,;.33,-6.93,;1.66,-6.16,;3,-6.93,;1.66,-4.62,;3,-3.85,;3,-2.31,;3,-.77,;3,.77,;1.66,1.54,;1.66,3.08,;3,3.85,;3,5.39,;4.33,3.08,;4.33,1.54,;5.66,.77,;7,1.54,;8.33,.77,;8.33,-.77,;7,-1.54,;6.68,-3.05,;5.15,-3.21,;4.52,-1.8,;5.66,-.77,;7.71,-4.19,;7.23,-5.66,;9.21,-3.87,;.33,-3.85,;.33,-2.31,;-1.01,-4.62,;-2.34,-3.85,;-2.34,-2.31,;-2.34,-.77,;-6.34,4.62,;-7.67,5.39,;-7.67,6.93,;-9.21,5.39,;-8.44,4.06,)|

BDBM546085

CN(C1CCN(CC2(CF)CCC2)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546086

CN(C1CCN(CC(F)(F)Cl)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546087

CN(C1CCN(CC(C)(C)C(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546088

CN(C1CCN(CC2(CC2)C(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546089

CN(C1CCN(CC2(CCC2)C(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546091

CN(C1CCN(CC1)C1(COC1)C(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N

BDBM546092

Cc1nc2cnc(N3CCC(CC3)N(CC(F)F)C3COC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(=O)(=O)CC(F)F

BDBM546093

CN(C1CC(F)(F)C1)C1CCN(CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546094

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC(F)(F)F)c(=O)c2c1C#N

BDBM546095

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(N)=O)c(=O)c2c1C#N

BDBM546096

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC(F)(F)F)c(=O)c2c1C#N

BDBM546097

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(N)=O)c(=O)c2c1C#N

BDBM546098

CN(C1CCN(CC(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC(F)(F)F)c(=O)c2c1C#N

BDBM546099

CN(C1CCN(CC(F)(F)C2(O)CCC2)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546100

CN(C1CCN(CC1)C(C)(C)C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546101

CCN(C1CCN(CC1)C1CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546102

CCN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N

BDBM546103

CN(C1CCN(CC1)[C@H]1C[C@H](F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N |r,wU:8.8,wD:10.11,(-7.87,-3.66,;-6.54,-2.89,;-6.54,-1.35,;-7.87,-.58,;-7.87,.96,;-6.54,1.73,;-5.21,.96,;-5.21,-.58,;-6.54,3.27,;-7.63,4.36,;-6.54,5.45,;-6.54,6.99,;-5.45,4.36,;-5.21,-3.66,;-5.21,-5.2,;-3.87,-5.97,;-2.54,-5.2,;-1.2,-5.97,;.13,-5.2,;1.46,-5.97,;.13,-3.66,;1.46,-2.89,;1.46,-1.35,;1.46,.19,;1.46,1.73,;.13,2.5,;.13,4.04,;1.46,4.81,;1.46,6.35,;2.8,4.04,;2.8,2.5,;4.13,1.73,;5.46,2.5,;6.8,1.73,;6.8,.19,;5.46,-.58,;5.14,-2.09,;3.61,-2.25,;2.99,-.84,;4.13,.19,;6.17,-3.23,;7.68,-2.91,;5.7,-4.7,;6.73,-5.84,;7.76,-6.99,;7.87,-4.81,;5.58,-6.87,;-1.2,-2.89,;-1.2,-1.35,;-2.54,-3.66,;-3.87,-2.89,;-3.87,-1.35,;-3.87,.19,)|

BDBM546104

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C(F)(F)F)c(=O)c2c1C#N

BDBM546105

CCS(=O)(=O)NC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cnc(N(C)C3CCN(CC(F)(F)F)CC3)c(C#N)c2c1=O

BDBM546106

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C(C)(C)C)c(=O)c2c1C#N

BDBM546107

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N

BDBM546108

CCN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N

BDBM546109

CCN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3COC3)c(=O)c2c1C#N

BDBM546110

CCN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N

BDBM546111

CN(C1CCN(CC1)[C@@H]1C[C@@H](C1)OC(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3COC3)c(=O)c2c1C#N |r,wU:8.8,10.13,(-7.92,-4.05,;-6.59,-3.28,;-6.59,-1.74,;-7.92,-.97,;-7.92,.57,;-6.59,1.34,;-5.25,.57,;-5.25,-.97,;-6.59,2.88,;-5.5,3.97,;-6.59,5.06,;-7.67,3.97,;-6.59,6.6,;-7.92,7.37,;-7.92,8.91,;-9.25,6.6,;-9.25,8.14,;-5.25,-4.05,;-5.25,-5.59,;-3.92,-6.36,;-2.58,-5.59,;-1.25,-6.36,;.08,-5.59,;1.42,-6.36,;.08,-4.05,;1.42,-3.28,;1.42,-1.74,;1.42,-.2,;1.42,1.34,;.08,2.11,;.08,3.65,;1.42,4.42,;1.42,5.96,;2.75,3.65,;2.75,2.11,;4.08,1.34,;5.42,2.11,;6.75,1.34,;6.75,-.2,;5.42,-.97,;5.1,-2.47,;3.57,-2.63,;2.94,-1.23,;4.08,-.2,;6.13,-3.62,;7.63,-3.3,;5.65,-5.08,;6.68,-6.23,;7.83,-5.2,;5.54,-7.26,;7.71,-7.37,;7.71,-8.91,;9.25,-8.91,;9.25,-7.37,;-1.25,-3.28,;-1.25,-1.74,;-2.58,-4.05,;-3.92,-3.28,;-3.92,-1.74,;-3.92,-.2,)|

BDBM546112

CN(C1CCN(CC1)[C@@H]1C[C@@H](C1)OC(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N |r,wU:8.8,10.13,(-8.42,-3.51,;-7.08,-2.74,;-7.08,-1.2,;-8.42,-.43,;-8.42,1.11,;-7.08,1.88,;-5.75,1.11,;-5.75,-.43,;-7.08,3.42,;-5.99,4.51,;-7.08,5.6,;-8.17,4.51,;-7.08,7.14,;-8.42,7.91,;-8.42,9.45,;-9.75,7.14,;-9.75,8.68,;-5.75,-3.51,;-5.75,-5.05,;-4.42,-5.82,;-3.08,-5.05,;-1.75,-5.82,;-.42,-5.05,;.92,-5.82,;-.42,-3.51,;.92,-2.74,;.92,-1.2,;.92,.34,;.92,1.88,;-.42,2.65,;-.42,4.19,;.92,4.96,;.92,6.5,;2.25,4.19,;2.25,2.65,;3.59,1.88,;4.92,2.65,;6.25,1.88,;6.25,.34,;4.92,-.43,;4.6,-1.94,;3.07,-2.1,;2.44,-.69,;3.59,.34,;5.63,-3.08,;7.14,-2.76,;5.15,-4.55,;6.18,-5.69,;7.33,-4.66,;5.04,-6.72,;7.21,-6.84,;6.74,-8.3,;7.77,-9.45,;9.28,-9.13,;9.75,-7.66,;8.72,-6.52,;-1.75,-2.74,;-1.75,-1.2,;-3.08,-3.51,;-4.42,-2.74,;-4.42,-1.2,;-4.42,.34,)|

BDBM546113

CCOP(=O)(OCC)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(N3CCN(C)CC3)c(C#N)c2c1=O)C(F)(F)F

BDBM546114

CN1CCN(CC1)c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)P(O)(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM546115

CCOP(=O)(OCC)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(N3CCN(CC3)C3CC3)c(C#N)c2c1=O)C(F)(F)F

BDBM546116

Cc1nc2cc(c(N3CCN(CC3)C3CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)P(O)(O)=O)C(F)(F)F

BDBM546117

CCOP(=O)(OCC)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cnc(N(C)C3CCN(CC(F)F)CC3)c(C#N)c2c1=O

BDBM546118

CN(C1CCN(CC(F)F)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)P(O)(O)=O)c(=O)c2c1C#N

BDBM546121

COC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cnc(N(C)C3CCN(CC(F)(F)F)CC3)c(C#N)c2c1=O

BDBM546122

CN(C)Cc1nc(C)c2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546123

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(c(C#N)c3c2=O)-c2c(F)cccc2F)c2scc(C(O)=O)c2n1 |(9.33,2.7,;7.99,1.93,;6.66,2.7,;5.33,1.93,;3.99,2.7,;3.99,4.24,;2.66,5.01,;2.66,6.55,;1.33,4.24,;1.33,2.7,;2.66,1.93,;2.66,.39,;1.34,-.39,;1.34,-1.93,;.01,-2.7,;.01,-4.24,;1.34,-5.01,;-1.33,-5.01,;-2.66,-4.24,;-3.99,-5.01,;-3.99,-6.55,;-5.33,-4.24,;-5.33,-2.7,;-3.99,-1.93,;-3.99,-.39,;-3.99,1.15,;-2.66,-2.7,;-1.33,-1.93,;-1.33,-.39,;-6.66,-1.93,;-6.66,-.39,;-5.33,.38,;-7.99,.38,;-9.33,-.39,;-9.33,-1.93,;-7.99,-2.7,;-7.99,-4.24,;5.33,.39,;4.18,-.64,;4.81,-2.05,;6.34,-1.89,;7.37,-3.03,;6.89,-4.49,;8.88,-2.71,;6.66,-.38,;7.99,.39,)|

BDBM546124

Cc1nc2c(C)nc(N3CCN(CCF)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546125

Cc1nc2cnc(C3=CCNCC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |t:7|

BDBM546126

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(N[N+](C)(C)C)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM546127

Cc1nc2cnc(N3CC4(CN(CCC(F)(F)F)C4)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546128

Cc1nc2cnc(N3CC4(CNC4)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546129

Cc1nc2cnc(N3CC4(CCN4CC(F)F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546130

Cc1nc2cnc(N3CC4(CCN4CC(C)(C)F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546131

Cc1nc2cnc(N3CCC4(CCN4CC(F)F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546132

CC(C)N1CCN(CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546133

Cc1nc2cnc(N3CCN(CC3)C3CC3(C)C)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546134

Cc1nc2cnc(N3CCN(CC3)C3CCC3(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546135

Cc1nc2cnc(N3CCN(CC3)C3(C)CC(F)(F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546136

Cc1nc2cnc(N3CCN(CC3)[C@H]3C[C@@H]3C(F)(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |r|

BDBM546137

Cc1nc2cnc(N3CCN(CC3)C3(CC(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546138

Cc1nc2cnc(N3CC[N+](CCO)(CC3)C(F)F)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546139

CN1CC2CC1CN2c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546140

Cc1nc2cnc(N3CCN(C4CC4)C4(CC4)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546141

Cc1nc2cnc(N3CCC4(CCN4CC(F)F)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546143

Cc1nc2cnc(N3CCCC4(CCN4CC(F)F)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546144

Cc1nc2cnc(N3CCC(C)(CC3)N3CC(F)(F)C3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546145

CN(C1CCN(CCF)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546146

CC(F)CN1CCC(CC1)N(C)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546147

CN(C1CCN(CC(C)(C)F)CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546148

CC(C(F)F)N1CCC(CC1)N(C)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546149

Cc1nc2cnc(NC3CC[N+](C)(CC(F)F)CC3)c(C#N)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O |(2.23,-6.16,;.89,-5.39,;-.44,-6.16,;-1.78,-5.39,;-3.11,-6.16,;-4.44,-5.39,;-4.44,-3.85,;-5.78,-3.08,;-5.78,-1.54,;-4.44,-.77,;-4.44,.77,;-5.78,1.54,;-4.44,2.31,;-5.78,3.08,;-7.11,3.85,;-7.11,5.39,;-8.44,3.08,;-7.11,.77,;-7.11,-.77,;-3.11,-3.08,;-3.11,-1.54,;-3.11,,;-1.78,-3.85,;-.44,-3.08,;-.44,-1.54,;.89,-3.85,;2.23,-3.08,;2.23,-1.54,;2.23,,;2.23,1.54,;.89,2.31,;.89,3.85,;2.23,4.62,;2.23,6.16,;3.56,3.85,;3.56,2.31,;4.89,1.54,;6.23,2.31,;7.56,1.54,;7.56,,;6.23,-.77,;5.91,-2.28,;4.38,-2.44,;3.75,-1.03,;4.89,,;6.94,-3.42,;8.44,-3.1,;6.46,-4.89,)|

BDBM546150

CC1C[C@H]2C[C@@H](C[C@@H]1N2CC(F)F)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,THB:9:8:5.4.6:1.2|

BDBM546151

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cn(C)cn3)c(=O)c2c1C#N

BDBM546152

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccnn3C)c(=O)c2c1C#N

BDBM546153

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CF)c(=O)c2c1C#N

BDBM546154

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC#N)c(=O)c2c1C#N

BDBM546155

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CCC#N)c(=O)c2c1C#N

BDBM546156

CN(C1CCN(CC(F)(F)F)CC1)C1=C(C#N)c2c(CN1)nc(C)n(CC#Cc1ccc(Cl)cc1-c1ccnc3c(csc13)C(=O)NS(=O)(=O)CC(C)(C)C#N)c2=O |c:14|

BDBM546157

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)Cc3ccccn3)c(=O)c2c1C#N

BDBM546158

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccc(nc3)C(F)(F)F)c(=O)c2c1C#N

BDBM546159

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cscn3)c(=O)c2c1C#N

BDBM546160

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccn(C)n3)c(=O)c2c1C#N

BDBM546161

CN(C1CCN(CC(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3CC(F)(F)C3)c(=O)c2c1C#N

BDBM546162

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cccc(C)n3)c(=O)c2c1C#N

BDBM546163

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccc(cn3)C(F)(F)F)c(=O)c2c1C#N

BDBM546164

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccc(C)nc3)c(=O)c2c1C#N

BDBM546165

COc1ccc(cn1)S(=O)(=O)NC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cnc(N(C)C3CCN(CC(C)(F)F)CC3)c(C#N)c2c1=O

BDBM546166

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccnc(C)c3)c(=O)c2c1C#N

BDBM546167

COc1cc(ccn1)S(=O)(=O)NC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cnc(N(C)C3CCN(CC(C)(F)F)CC3)c(C#N)c2c1=O

BDBM546168

CN(C1C[C@H]2C[C@@H]1CN2CC(C)(F)F)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM546169

CN(C1C[C@H]2C[C@@H]1CN2CC(C)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM546170

CN([C@@H]1[C@H]2CC[C@@H]1CN(CC(C)(F)F)C2)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM546171

CN(C1[C@H]2C[C@@H]1CN(CC(C)(F)F)C2)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM546172

CN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N

BDBM546173

CN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3COC3)c(=O)c2c1C#N

BDBM546174

CN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccncc3)c(=O)c2c1C#N

BDBM546175

CN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N

BDBM546176

CN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cccnc3)c(=O)c2c1C#N

BDBM546177

CCN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccncc3)c(=O)c2c1C#N

BDBM546178

CCN(C1CCN(CC(F)(F)C(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cccnc3)c(=O)c2c1C#N

BDBM546179

CN(C1CCN(CCC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N

BDBM546180

CN(C1CCN(CC2(CCO2)C(F)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546181

CN(C1CCN(CC1)[C@H]1C[C@@H]1C(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM546183

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC)c(=O)c2c1C#N

BDBM546184

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC(F)(F)F)c(=O)c2c1C#N

BDBM546185

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC#N)c(=O)c2c1C#N

BDBM546186

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CCC#N)c(=O)c2c1C#N

BDBM546187

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC(C)(C)C#N)c(=O)c2c1C#N

BDBM546188

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)Cc3ccccn3)c(=O)c2c1C#N

BDBM546189

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3CC(F)(F)C3)c(=O)c2c1C#N

BDBM546190

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccncc3)c(=O)c2c1C#N

BDBM546191

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cccnc3)c(=O)c2c1C#N

BDBM546192

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N

BDBM546193

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CF)c(=O)c2c1C#N

BDBM546194

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C(F)(F)F)c(=O)c2c1C#N

BDBM546195

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC(F)F)c(=O)c2c1C#N

BDBM546196

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C(C)C)c(=O)c2c1C#N

BDBM546197

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C(C)(C)C)c(=O)c2c1C#N

BDBM546198

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3CCC3)c(=O)c2c1C#N

BDBM546199

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3CC3)c(=O)c2c1C#N

BDBM546200

CCN(C1CCN(CC1)C1COC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3COC3)c(=O)c2c1C#N

BDBM546201

CN(C1CCN(CC1)[C@H]1C[C@@H](C1)OC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N |r,wU:8.8,wD:10.13,(-7.21,-4.82,;-5.87,-4.05,;-5.87,-2.51,;-7.21,-1.74,;-7.21,-.2,;-5.87,.57,;-4.54,-.2,;-4.54,-1.74,;-5.87,2.11,;-6.96,3.2,;-5.87,4.29,;-4.78,3.2,;-5.87,5.83,;-7.21,6.6,;-7.21,8.14,;-8.54,5.83,;-4.54,-4.82,;-4.54,-6.36,;-3.21,-7.13,;-1.87,-6.36,;-.54,-7.13,;.8,-6.36,;2.13,-7.13,;.8,-4.82,;2.13,-4.05,;2.13,-2.51,;2.13,-.97,;2.13,.57,;.8,1.34,;.8,2.88,;2.13,3.65,;2.13,5.19,;3.46,2.88,;3.46,1.34,;4.8,.57,;6.13,1.34,;7.46,.57,;7.46,-.97,;6.13,-1.74,;5.81,-3.24,;4.28,-3.4,;3.65,-2,;4.8,-.97,;6.84,-4.39,;8.35,-4.07,;6.36,-5.85,;7.4,-7,;8.43,-8.14,;8.54,-5.97,;6.25,-8.03,;-.54,-4.05,;-.54,-2.51,;-1.87,-4.82,;-3.21,-4.05,;-3.21,-2.51,;-3.21,-.97,)|

BDBM546202

CN(C1CCN(CC1)[C@H]1C[C@@H](C1)OC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3COC3)c(=O)c2c1C#N |r,wU:8.8,wD:10.13,(-7.92,-4.05,;-6.59,-3.28,;-6.59,-1.74,;-7.92,-.97,;-7.92,.57,;-6.59,1.34,;-5.25,.57,;-5.25,-.97,;-6.59,2.88,;-7.67,3.97,;-6.59,5.06,;-5.5,3.97,;-6.59,6.6,;-7.92,7.37,;-7.92,8.91,;-9.25,6.6,;-5.25,-4.05,;-5.25,-5.59,;-3.92,-6.36,;-2.58,-5.59,;-1.25,-6.36,;.08,-5.59,;1.42,-6.36,;.08,-4.05,;1.42,-3.28,;1.42,-1.74,;1.42,-.2,;1.42,1.34,;.08,2.11,;.08,3.65,;1.42,4.42,;1.42,5.96,;2.75,3.65,;2.75,2.11,;4.08,1.34,;5.42,2.11,;6.75,1.34,;6.75,-.2,;5.42,-.97,;5.1,-2.47,;3.57,-2.63,;2.94,-1.23,;4.08,-.2,;6.13,-3.62,;7.63,-3.3,;5.65,-5.08,;6.68,-6.23,;7.83,-5.2,;5.54,-7.26,;7.71,-7.37,;7.71,-8.91,;9.25,-8.91,;9.25,-7.37,;-1.25,-3.28,;-1.25,-1.74,;-2.58,-4.05,;-3.92,-3.28,;-3.92,-1.74,;-3.92,-.2,)|

BDBM546203

CN(C1CCN(CC1)[C@H]1C[C@@H](C1)OC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N |r,wU:8.8,wD:10.13,(-8.42,-3.51,;-7.08,-2.74,;-7.08,-1.2,;-8.42,-.43,;-8.42,1.11,;-7.08,1.88,;-5.75,1.11,;-5.75,-.43,;-7.08,3.42,;-8.17,4.51,;-7.08,5.6,;-5.99,4.51,;-7.08,7.14,;-8.42,7.91,;-8.42,9.45,;-9.75,7.14,;-5.75,-3.51,;-5.75,-5.05,;-4.42,-5.82,;-3.08,-5.05,;-1.75,-5.82,;-.42,-5.05,;.92,-5.82,;-.42,-3.51,;.92,-2.74,;.92,-1.2,;.92,.34,;.92,1.88,;-.42,2.65,;-.42,4.19,;.92,4.96,;.92,6.5,;2.25,4.19,;2.25,2.65,;3.59,1.88,;4.92,2.65,;6.25,1.88,;6.25,.34,;4.92,-.43,;4.6,-1.94,;3.07,-2.1,;2.44,-.69,;3.59,.34,;5.63,-3.08,;7.14,-2.76,;5.15,-4.55,;6.18,-5.69,;7.33,-4.66,;5.04,-6.72,;7.21,-6.84,;6.74,-8.3,;7.77,-9.45,;9.28,-9.13,;9.75,-7.66,;8.72,-6.52,;-1.75,-2.74,;-1.75,-1.2,;-3.08,-3.51,;-4.42,-2.74,;-4.42,-1.2,;-4.42,.34,)|

BDBM546204

CN(C1CCN(CC1)[C@H]1C[C@@H](C1)OC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccncc3)c(=O)c2c1C#N |r,wU:8.8,wD:10.13,(-8.42,-3.51,;-7.08,-2.74,;-7.08,-1.2,;-8.42,-.43,;-8.42,1.11,;-7.08,1.88,;-5.75,1.11,;-5.75,-.43,;-7.08,3.42,;-8.17,4.51,;-7.08,5.6,;-5.99,4.51,;-7.08,7.14,;-8.42,7.91,;-8.42,9.45,;-9.75,7.14,;-5.75,-3.51,;-5.75,-5.05,;-4.42,-5.82,;-3.08,-5.05,;-1.75,-5.82,;-.42,-5.05,;.92,-5.82,;-.42,-3.51,;.92,-2.74,;.92,-1.2,;.92,.34,;.92,1.88,;-.42,2.65,;-.42,4.19,;.92,4.96,;.92,6.5,;2.25,4.19,;2.25,2.65,;3.59,1.88,;4.92,2.65,;6.25,1.88,;6.25,.34,;4.92,-.43,;4.6,-1.94,;3.07,-2.1,;2.44,-.69,;3.59,.34,;5.63,-3.08,;7.14,-2.76,;5.15,-4.55,;6.18,-5.69,;7.33,-4.66,;5.04,-6.72,;7.21,-6.84,;6.74,-8.3,;7.77,-9.45,;9.28,-9.13,;9.75,-7.66,;8.72,-6.52,;-1.75,-2.74,;-1.75,-1.2,;-3.08,-3.51,;-4.42,-2.74,;-4.42,-1.2,;-4.42,.34,)|

BDBM546205

CN(C1CCN(CC1)[C@H]1C[C@@H](C1)OC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cccnc3)c(=O)c2c1C#N |r,wU:8.8,wD:10.13,(-8.42,-3.51,;-7.08,-2.74,;-7.08,-1.2,;-8.42,-.43,;-8.42,1.11,;-7.08,1.88,;-5.75,1.11,;-5.75,-.43,;-7.08,3.42,;-8.17,4.51,;-7.08,5.6,;-5.99,4.51,;-7.08,7.14,;-8.42,7.91,;-8.42,9.45,;-9.75,7.14,;-5.75,-3.51,;-5.75,-5.05,;-4.42,-5.82,;-3.08,-5.05,;-1.75,-5.82,;-.42,-5.05,;.92,-5.82,;-.42,-3.51,;.92,-2.74,;.92,-1.2,;.92,.34,;.92,1.88,;-.42,2.65,;-.42,4.19,;.92,4.96,;.92,6.5,;2.25,4.19,;2.25,2.65,;3.59,1.88,;4.92,2.65,;6.25,1.88,;6.25,.34,;4.92,-.43,;4.6,-1.94,;3.07,-2.1,;2.44,-.69,;3.59,.34,;5.63,-3.08,;7.14,-2.76,;5.15,-4.55,;6.18,-5.69,;7.33,-4.66,;5.04,-6.72,;7.21,-6.84,;6.74,-8.3,;7.77,-9.45,;9.28,-9.13,;9.75,-7.66,;8.72,-6.52,;-1.75,-2.74,;-1.75,-1.2,;-3.08,-3.51,;-4.42,-2.74,;-4.42,-1.2,;-4.42,.34,)|

BDBM546206

CCN(C1CCN(CC1)[C@H]1C[C@@H](C1)OC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N |r,wU:9.9,wD:11.14,(-8.54,-4.05,;-7.21,-4.82,;-5.87,-4.05,;-5.87,-2.51,;-7.21,-1.74,;-7.21,-.2,;-5.87,.57,;-4.54,-.2,;-4.54,-1.74,;-5.87,2.11,;-6.96,3.2,;-5.87,4.29,;-4.78,3.2,;-5.87,5.83,;-7.21,6.6,;-7.21,8.14,;-8.54,5.83,;-4.54,-4.82,;-4.54,-6.36,;-3.21,-7.13,;-1.87,-6.36,;-.54,-7.13,;.8,-6.36,;2.13,-7.13,;.8,-4.82,;2.13,-4.05,;2.13,-2.51,;2.13,-.97,;2.13,.57,;.8,1.34,;.8,2.88,;2.13,3.65,;2.13,5.19,;3.46,2.88,;3.46,1.34,;4.8,.57,;6.13,1.34,;7.46,.57,;7.46,-.97,;6.13,-1.74,;5.81,-3.24,;4.28,-3.4,;3.65,-2,;4.8,-.97,;6.84,-4.39,;8.35,-4.07,;6.36,-5.85,;7.4,-7,;8.43,-8.14,;8.54,-5.97,;6.25,-8.03,;-.54,-4.05,;-.54,-2.51,;-1.87,-4.82,;-3.21,-4.05,;-3.21,-2.51,;-3.21,-.97,)|

BDBM546207

CCN(C1CCN(CC1)[C@H]1C[C@@H](C1)OC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3COC3)c(=O)c2c1C#N |r,wU:9.9,wD:11.14,(-9.25,-3.28,;-7.92,-4.05,;-6.59,-3.28,;-6.59,-1.74,;-7.92,-.97,;-7.92,.57,;-6.59,1.34,;-5.25,.57,;-5.25,-.97,;-6.59,2.88,;-7.67,3.97,;-6.59,5.06,;-5.5,3.97,;-6.59,6.6,;-7.92,7.37,;-7.92,8.91,;-9.25,6.6,;-5.25,-4.05,;-5.25,-5.59,;-3.92,-6.36,;-2.58,-5.59,;-1.25,-6.36,;.08,-5.59,;1.42,-6.36,;.08,-4.05,;1.42,-3.28,;1.42,-1.74,;1.42,-.2,;1.42,1.34,;.08,2.11,;.08,3.65,;1.42,4.42,;1.42,5.96,;2.75,3.65,;2.75,2.11,;4.08,1.34,;5.42,2.11,;6.75,1.34,;6.75,-.2,;5.42,-.97,;5.1,-2.47,;3.57,-2.63,;2.94,-1.23,;4.08,-.2,;6.13,-3.62,;7.63,-3.3,;5.65,-5.08,;6.68,-6.23,;7.83,-5.2,;5.54,-7.26,;7.71,-7.37,;7.71,-8.91,;9.25,-8.91,;9.25,-7.37,;-1.25,-3.28,;-1.25,-1.74,;-2.58,-4.05,;-3.92,-3.28,;-3.92,-1.74,;-3.92,-.2,)|

BDBM546208

CCN(C1CCN(CC1)[C@H]1C[C@@H](C1)OC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccncc3)c(=O)c2c1C#N |r,wU:9.9,wD:11.14,(-9.75,-2.74,;-8.42,-3.51,;-7.08,-2.74,;-7.08,-1.2,;-8.42,-.43,;-8.42,1.11,;-7.08,1.88,;-5.75,1.11,;-5.75,-.43,;-7.08,3.42,;-8.17,4.51,;-7.08,5.6,;-5.99,4.51,;-7.08,7.14,;-8.42,7.91,;-8.42,9.45,;-9.75,7.14,;-5.75,-3.51,;-5.75,-5.05,;-4.42,-5.82,;-3.08,-5.05,;-1.75,-5.82,;-.42,-5.05,;.92,-5.82,;-.42,-3.51,;.92,-2.74,;.92,-1.2,;.92,.34,;.92,1.88,;-.42,2.65,;-.42,4.19,;.92,4.96,;.92,6.5,;2.25,4.19,;2.25,2.65,;3.59,1.88,;4.92,2.65,;6.25,1.88,;6.25,.34,;4.92,-.43,;4.6,-1.94,;3.07,-2.1,;2.44,-.69,;3.59,.34,;5.63,-3.08,;7.14,-2.76,;5.15,-4.55,;6.18,-5.69,;7.33,-4.66,;5.04,-6.72,;7.21,-6.84,;6.74,-8.3,;7.77,-9.45,;9.28,-9.13,;9.75,-7.66,;8.72,-6.52,;-1.75,-2.74,;-1.75,-1.2,;-3.08,-3.51,;-4.42,-2.74,;-4.42,-1.2,;-4.42,.34,)|

BDBM546209

CCN(C1CCN(CC1)[C@H]1C[C@@H](C1)OC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cccnc3)c(=O)c2c1C#N |r,wU:9.9,wD:11.14,(-9.75,-2.74,;-8.42,-3.51,;-7.08,-2.74,;-7.08,-1.2,;-8.42,-.43,;-8.42,1.11,;-7.08,1.88,;-5.75,1.11,;-5.75,-.43,;-7.08,3.42,;-8.17,4.51,;-7.08,5.6,;-5.99,4.51,;-7.08,7.14,;-8.42,7.91,;-8.42,9.45,;-9.75,7.14,;-5.75,-3.51,;-5.75,-5.05,;-4.42,-5.82,;-3.08,-5.05,;-1.75,-5.82,;-.42,-5.05,;.92,-5.82,;-.42,-3.51,;.92,-2.74,;.92,-1.2,;.92,.34,;.92,1.88,;-.42,2.65,;-.42,4.19,;.92,4.96,;.92,6.5,;2.25,4.19,;2.25,2.65,;3.59,1.88,;4.92,2.65,;6.25,1.88,;6.25,.34,;4.92,-.43,;4.6,-1.94,;3.07,-2.1,;2.44,-.69,;3.59,.34,;5.63,-3.08,;7.14,-2.76,;5.15,-4.55,;6.18,-5.69,;7.33,-4.66,;5.04,-6.72,;7.21,-6.84,;6.74,-8.3,;7.77,-9.45,;9.28,-9.13,;9.75,-7.66,;8.72,-6.52,;-1.75,-2.74,;-1.75,-1.2,;-3.08,-3.51,;-4.42,-2.74,;-4.42,-1.2,;-4.42,.34,)|

BDBM546210

CCN(C1CCN(CC1)[C@H]1C[C@@H](C1)OC(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N |r,wU:9.9,wD:11.14,(-9.75,-2.74,;-8.42,-3.51,;-7.08,-2.74,;-7.08,-1.2,;-8.42,-.43,;-8.42,1.11,;-7.08,1.88,;-5.75,1.11,;-5.75,-.43,;-7.08,3.42,;-8.17,4.51,;-7.08,5.6,;-5.99,4.51,;-7.08,7.14,;-8.42,7.91,;-8.42,9.45,;-9.75,7.14,;-5.75,-3.51,;-5.75,-5.05,;-4.42,-5.82,;-3.08,-5.05,;-1.75,-5.82,;-.42,-5.05,;.92,-5.82,;-.42,-3.51,;.92,-2.74,;.92,-1.2,;.92,.34,;.92,1.88,;-.42,2.65,;-.42,4.19,;.92,4.96,;.92,6.5,;2.25,4.19,;2.25,2.65,;3.59,1.88,;4.92,2.65,;6.25,1.88,;6.25,.34,;4.92,-.43,;4.6,-1.94,;3.07,-2.1,;2.44,-.69,;3.59,.34,;5.63,-3.08,;7.14,-2.76,;5.15,-4.55,;6.18,-5.69,;7.33,-4.66,;5.04,-6.72,;7.21,-6.84,;6.74,-8.3,;7.77,-9.45,;9.28,-9.13,;9.75,-7.66,;8.72,-6.52,;-1.75,-2.74,;-1.75,-1.2,;-3.08,-3.51,;-4.42,-2.74,;-4.42,-1.2,;-4.42,.34,)|

BDBM546211

CN(C1CCN(CC1)[C@@H]1C[C@@H](C1)OC(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N |r,wU:8.8,10.13,(-7.21,-4.82,;-5.87,-4.05,;-5.87,-2.51,;-7.21,-1.74,;-7.21,-.2,;-5.87,.57,;-4.54,-.2,;-4.54,-1.74,;-5.87,2.11,;-4.78,3.2,;-5.87,4.29,;-6.96,3.2,;-5.87,5.83,;-7.21,6.6,;-7.21,8.14,;-8.54,5.83,;-8.54,7.37,;-4.54,-4.82,;-4.54,-6.36,;-3.21,-7.13,;-1.87,-6.36,;-.54,-7.13,;.8,-6.36,;2.13,-7.13,;.8,-4.82,;2.13,-4.05,;2.13,-2.51,;2.13,-.97,;2.13,.57,;.8,1.34,;.8,2.88,;2.13,3.65,;2.13,5.19,;3.46,2.88,;3.46,1.34,;4.8,.57,;6.13,1.34,;7.46,.57,;7.46,-.97,;6.13,-1.74,;5.81,-3.24,;4.28,-3.4,;3.65,-2,;4.8,-.97,;6.84,-4.39,;8.35,-4.07,;6.36,-5.85,;7.4,-7,;8.43,-8.14,;8.54,-5.97,;6.25,-8.03,;-.54,-4.05,;-.54,-2.51,;-1.87,-4.82,;-3.21,-4.05,;-3.21,-2.51,;-3.21,-.97,)|

BDBM546212

CN(C1CCN(CC1)[C@@H]1C[C@@H](C1)OC(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccncc3)c(=O)c2c1C#N |r,wU:8.8,10.13,(-8.42,-3.51,;-7.08,-2.74,;-7.08,-1.2,;-8.42,-.43,;-8.42,1.11,;-7.08,1.88,;-5.75,1.11,;-5.75,-.43,;-7.08,3.42,;-5.99,4.51,;-7.08,5.6,;-8.17,4.51,;-7.08,7.14,;-8.42,7.91,;-8.42,9.45,;-9.75,7.14,;-9.75,8.68,;-5.75,-3.51,;-5.75,-5.05,;-4.42,-5.82,;-3.08,-5.05,;-1.75,-5.82,;-.42,-5.05,;.92,-5.82,;-.42,-3.51,;.92,-2.74,;.92,-1.2,;.92,.34,;.92,1.88,;-.42,2.65,;-.42,4.19,;.92,4.96,;.92,6.5,;2.25,4.19,;2.25,2.65,;3.59,1.88,;4.92,2.65,;6.25,1.88,;6.25,.34,;4.92,-.43,;4.6,-1.94,;3.07,-2.1,;2.44,-.69,;3.59,.34,;5.63,-3.08,;7.14,-2.76,;5.15,-4.55,;6.18,-5.69,;7.33,-4.66,;5.04,-6.72,;7.21,-6.84,;6.74,-8.3,;7.77,-9.45,;9.28,-9.13,;9.75,-7.66,;8.72,-6.52,;-1.75,-2.74,;-1.75,-1.2,;-3.08,-3.51,;-4.42,-2.74,;-4.42,-1.2,;-4.42,.34,)|

BDBM546213

CN(C1CCN(CC1)[C@@H]1C[C@@H](C1)OC(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cccnc3)c(=O)c2c1C#N |r,wU:8.8,10.13,(-8.42,-3.51,;-7.08,-2.74,;-7.08,-1.2,;-8.42,-.43,;-8.42,1.11,;-7.08,1.88,;-5.75,1.11,;-5.75,-.43,;-7.08,3.42,;-5.99,4.51,;-7.08,5.6,;-8.17,4.51,;-7.08,7.14,;-8.42,7.91,;-8.42,9.45,;-9.75,7.14,;-9.75,8.68,;-5.75,-3.51,;-5.75,-5.05,;-4.42,-5.82,;-3.08,-5.05,;-1.75,-5.82,;-.42,-5.05,;.92,-5.82,;-.42,-3.51,;.92,-2.74,;.92,-1.2,;.92,.34,;.92,1.88,;-.42,2.65,;-.42,4.19,;.92,4.96,;.92,6.5,;2.25,4.19,;2.25,2.65,;3.59,1.88,;4.92,2.65,;6.25,1.88,;6.25,.34,;4.92,-.43,;4.6,-1.94,;3.07,-2.1,;2.44,-.69,;3.59,.34,;5.63,-3.08,;7.14,-2.76,;5.15,-4.55,;6.18,-5.69,;7.33,-4.66,;5.04,-6.72,;7.21,-6.84,;6.74,-8.3,;7.77,-9.45,;9.28,-9.13,;9.75,-7.66,;8.72,-6.52,;-1.75,-2.74,;-1.75,-1.2,;-3.08,-3.51,;-4.42,-2.74,;-4.42,-1.2,;-4.42,.34,)|

BDBM546214

CCN(C1CCN(CC1)[C@@H]1C[C@@H](C1)OC(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:9.9,11.14,(-8.44,-4.55,;-7.11,-5.32,;-5.78,-4.55,;-5.78,-3.01,;-7.11,-2.24,;-7.11,-.7,;-5.78,.07,;-4.44,-.7,;-4.44,-2.24,;-5.78,1.61,;-4.69,2.7,;-5.78,3.78,;-6.87,2.7,;-5.78,5.32,;-7.11,6.09,;-7.11,7.63,;-8.44,5.32,;-8.44,6.86,;-4.44,-5.32,;-4.44,-6.86,;-3.11,-7.63,;-1.78,-6.86,;-.44,-7.63,;.89,-6.86,;2.23,-7.63,;.89,-5.32,;2.23,-4.55,;2.23,-3.01,;2.23,-1.47,;2.23,.07,;.89,.84,;.89,2.38,;2.23,3.15,;2.23,4.69,;3.56,2.38,;3.56,.84,;4.89,.07,;6.23,.84,;7.56,.07,;7.56,-1.47,;6.23,-2.24,;5.91,-3.75,;4.38,-3.91,;3.75,-2.5,;4.89,-1.47,;6.94,-4.89,;6.46,-6.36,;8.44,-4.57,;-.44,-4.55,;-.44,-3.01,;-1.78,-5.32,;-3.11,-4.55,;-3.11,-3.01,;-3.11,-1.47,)|

BDBM546215

CCN(C1CCN(CC1)[C@@H]1C[C@@H](C1)OC(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(C)(=O)=O)c(=O)c2c1C#N |r,wU:9.9,11.14,(-8.54,-4.05,;-7.21,-4.82,;-5.87,-4.05,;-5.87,-2.51,;-7.21,-1.74,;-7.21,-.2,;-5.87,.57,;-4.54,-.2,;-4.54,-1.74,;-5.87,2.11,;-4.78,3.2,;-5.87,4.29,;-6.96,3.2,;-5.87,5.83,;-7.21,6.6,;-7.21,8.14,;-8.54,5.83,;-8.54,7.37,;-4.54,-4.82,;-4.54,-6.36,;-3.21,-7.13,;-1.87,-6.36,;-.54,-7.13,;.8,-6.36,;2.13,-7.13,;.8,-4.82,;2.13,-4.05,;2.13,-2.51,;2.13,-.97,;2.13,.57,;.8,1.34,;.8,2.88,;2.13,3.65,;2.13,5.19,;3.46,2.88,;3.46,1.34,;4.8,.57,;6.13,1.34,;7.46,.57,;7.46,-.97,;6.13,-1.74,;5.81,-3.24,;4.28,-3.4,;3.65,-2,;4.8,-.97,;6.84,-4.39,;8.35,-4.07,;6.36,-5.85,;7.4,-7,;8.43,-8.14,;8.54,-5.97,;6.25,-8.03,;-.54,-4.05,;-.54,-2.51,;-1.87,-4.82,;-3.21,-4.05,;-3.21,-2.51,;-3.21,-.97,)|

BDBM546216

CCN(C1CCN(CC1)[C@@H]1C[C@@H](C1)OC(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccncc3)c(=O)c2c1C#N |r,wU:9.9,11.14,(-9.75,-2.74,;-8.42,-3.51,;-7.08,-2.74,;-7.08,-1.2,;-8.42,-.43,;-8.42,1.11,;-7.08,1.88,;-5.75,1.11,;-5.75,-.43,;-7.08,3.42,;-5.99,4.51,;-7.08,5.6,;-8.17,4.51,;-7.08,7.14,;-8.42,7.91,;-8.42,9.45,;-9.75,7.14,;-9.75,8.68,;-5.75,-3.51,;-5.75,-5.05,;-4.42,-5.82,;-3.08,-5.05,;-1.75,-5.82,;-.42,-5.05,;.92,-5.82,;-.42,-3.51,;.92,-2.74,;.92,-1.2,;.92,.34,;.92,1.88,;-.42,2.65,;-.42,4.19,;.92,4.96,;.92,6.5,;2.25,4.19,;2.25,2.65,;3.59,1.88,;4.92,2.65,;6.25,1.88,;6.25,.34,;4.92,-.43,;4.6,-1.94,;3.07,-2.1,;2.44,-.69,;3.59,.34,;5.63,-3.08,;7.14,-2.76,;5.15,-4.55,;6.18,-5.69,;7.33,-4.66,;5.04,-6.72,;7.21,-6.84,;6.74,-8.3,;7.77,-9.45,;9.28,-9.13,;9.75,-7.66,;8.72,-6.52,;-1.75,-2.74,;-1.75,-1.2,;-3.08,-3.51,;-4.42,-2.74,;-4.42,-1.2,;-4.42,.34,)|

BDBM546217

CCN(C1CCN(CC1)[C@@H]1C[C@@H](C1)OC(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cccnc3)c(=O)c2c1C#N |r,wU:9.9,11.14,(-9.75,-2.74,;-8.42,-3.51,;-7.08,-2.74,;-7.08,-1.2,;-8.42,-.43,;-8.42,1.11,;-7.08,1.88,;-5.75,1.11,;-5.75,-.43,;-7.08,3.42,;-5.99,4.51,;-7.08,5.6,;-8.17,4.51,;-7.08,7.14,;-8.42,7.91,;-8.42,9.45,;-9.75,7.14,;-9.75,8.68,;-5.75,-3.51,;-5.75,-5.05,;-4.42,-5.82,;-3.08,-5.05,;-1.75,-5.82,;-.42,-5.05,;.92,-5.82,;-.42,-3.51,;.92,-2.74,;.92,-1.2,;.92,.34,;.92,1.88,;-.42,2.65,;-.42,4.19,;.92,4.96,;.92,6.5,;2.25,4.19,;2.25,2.65,;3.59,1.88,;4.92,2.65,;6.25,1.88,;6.25,.34,;4.92,-.43,;4.6,-1.94,;3.07,-2.1,;2.44,-.69,;3.59,.34,;5.63,-3.08,;7.14,-2.76,;5.15,-4.55,;6.18,-5.69,;7.33,-4.66,;5.04,-6.72,;7.21,-6.84,;6.74,-8.3,;7.77,-9.45,;9.28,-9.13,;9.75,-7.66,;8.72,-6.52,;-1.75,-2.74,;-1.75,-1.2,;-3.08,-3.51,;-4.42,-2.74,;-4.42,-1.2,;-4.42,.34,)|

BDBM546218

CCN(C1CCN(CC1)[C@@H]1C[C@@H](C1)OC(F)(F)F)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N |r,wU:9.9,11.14,(-9.75,-2.74,;-8.42,-3.51,;-7.08,-2.74,;-7.08,-1.2,;-8.42,-.43,;-8.42,1.11,;-7.08,1.88,;-5.75,1.11,;-5.75,-.43,;-7.08,3.42,;-5.99,4.51,;-7.08,5.6,;-8.17,4.51,;-7.08,7.14,;-8.42,7.91,;-8.42,9.45,;-9.75,7.14,;-9.75,8.68,;-5.75,-3.51,;-5.75,-5.05,;-4.42,-5.82,;-3.08,-5.05,;-1.75,-5.82,;-.42,-5.05,;.92,-5.82,;-.42,-3.51,;.92,-2.74,;.92,-1.2,;.92,.34,;.92,1.88,;-.42,2.65,;-.42,4.19,;.92,4.96,;.92,6.5,;2.25,4.19,;2.25,2.65,;3.59,1.88,;4.92,2.65,;6.25,1.88,;6.25,.34,;4.92,-.43,;4.6,-1.94,;3.07,-2.1,;2.44,-.69,;3.59,.34,;5.63,-3.08,;7.14,-2.76,;5.15,-4.55,;6.18,-5.69,;7.33,-4.66,;5.04,-6.72,;7.21,-6.84,;6.74,-8.3,;7.77,-9.45,;9.28,-9.13,;9.75,-7.66,;8.72,-6.52,;-1.75,-2.74,;-1.75,-1.2,;-3.08,-3.51,;-4.42,-2.74,;-4.42,-1.2,;-4.42,.34,)|

BDBM546219

CN(C1CCN(CC1)[C@H]1C[C@H](F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3COC3)c(=O)c2c1C#N |r,wU:8.8,wD:10.11,(-8.59,-2.89,;-7.25,-2.12,;-7.25,-.58,;-8.59,.19,;-8.59,1.73,;-7.25,2.5,;-5.92,1.73,;-5.92,.19,;-7.25,4.04,;-8.34,5.13,;-7.25,6.22,;-7.25,7.76,;-6.16,5.13,;-5.92,-2.89,;-5.92,-4.43,;-4.59,-5.2,;-3.25,-4.43,;-1.92,-5.2,;-.58,-4.43,;.75,-5.2,;-.58,-2.89,;.75,-2.12,;.75,-.58,;.75,.96,;.75,2.5,;-.58,3.27,;-.58,4.81,;.75,5.58,;.75,7.12,;2.08,4.81,;2.08,3.27,;3.42,2.5,;4.75,3.27,;6.08,2.5,;6.08,.96,;4.75,.19,;4.43,-1.32,;2.9,-1.48,;2.27,-.07,;3.42,.96,;5.46,-2.46,;6.97,-2.14,;4.99,-3.93,;6.02,-5.07,;7.16,-4.04,;4.87,-6.1,;7.05,-6.22,;7.05,-7.76,;8.59,-7.76,;8.59,-6.22,;-1.92,-2.12,;-1.92,-.58,;-3.25,-2.89,;-4.59,-2.12,;-4.59,-.58,;-4.59,.96,)|

BDBM546220

CN(C1CCN(CC1)[C@H]1C[C@H](F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccncc3)c(=O)c2c1C#N |r,wU:8.8,wD:10.11,(-9.08,-2.36,;-7.75,-1.59,;-7.75,-.05,;-9.08,.72,;-9.08,2.26,;-7.75,3.03,;-6.42,2.26,;-6.42,.72,;-7.75,4.57,;-8.84,5.66,;-7.75,6.75,;-7.75,8.29,;-6.66,5.66,;-6.42,-2.36,;-6.42,-3.9,;-5.08,-4.67,;-3.75,-3.9,;-2.42,-4.67,;-1.08,-3.9,;.25,-4.67,;-1.08,-2.36,;.25,-1.59,;.25,-.05,;.25,1.49,;.25,3.03,;-1.08,3.8,;-1.08,5.34,;.25,6.11,;.25,7.65,;1.58,5.34,;1.58,3.8,;2.92,3.03,;4.25,3.8,;5.59,3.03,;5.59,1.49,;4.25,.72,;3.93,-.78,;2.4,-.94,;1.77,.46,;2.92,1.49,;4.96,-1.93,;6.47,-1.61,;4.49,-3.39,;5.52,-4.54,;6.66,-3.51,;4.37,-5.57,;6.55,-5.68,;6.07,-7.15,;7.1,-8.29,;8.61,-7.97,;9.08,-6.51,;8.05,-5.36,;-2.42,-1.59,;-2.42,-.05,;-3.75,-2.36,;-5.08,-1.59,;-5.08,-.05,;-5.08,1.49,)|

BDBM546221

CN(C1CCN(CC1)[C@H]1C[C@H](F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N |r,wU:8.8,wD:10.11,(-9.08,-2.36,;-7.75,-1.59,;-7.75,-.05,;-9.08,.72,;-9.08,2.26,;-7.75,3.03,;-6.42,2.26,;-6.42,.72,;-7.75,4.57,;-8.84,5.66,;-7.75,6.75,;-7.75,8.29,;-6.66,5.66,;-6.42,-2.36,;-6.42,-3.9,;-5.08,-4.67,;-3.75,-3.9,;-2.42,-4.67,;-1.08,-3.9,;.25,-4.67,;-1.08,-2.36,;.25,-1.59,;.25,-.05,;.25,1.49,;.25,3.03,;-1.08,3.8,;-1.08,5.34,;.25,6.11,;.25,7.65,;1.58,5.34,;1.58,3.8,;2.92,3.03,;4.25,3.8,;5.59,3.03,;5.59,1.49,;4.25,.72,;3.93,-.78,;2.4,-.94,;1.77,.46,;2.92,1.49,;4.96,-1.93,;6.47,-1.61,;4.49,-3.39,;5.52,-4.54,;6.66,-3.51,;4.37,-5.57,;6.55,-5.68,;6.07,-7.15,;7.1,-8.29,;8.61,-7.97,;9.08,-6.51,;8.05,-5.36,;-2.42,-1.59,;-2.42,-.05,;-3.75,-2.36,;-5.08,-1.59,;-5.08,-.05,;-5.08,1.49,)|

BDBM546222

CN(C1CCN(CC1)[C@H]1C[C@H](F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cccnc3)c(=O)c2c1C#N |r,wU:8.8,wD:10.11,(-9.08,-2.36,;-7.75,-1.59,;-7.75,-.05,;-9.08,.72,;-9.08,2.26,;-7.75,3.03,;-6.42,2.26,;-6.42,.72,;-7.75,4.57,;-8.84,5.66,;-7.75,6.75,;-7.75,8.29,;-6.66,5.66,;-6.42,-2.36,;-6.42,-3.9,;-5.08,-4.67,;-3.75,-3.9,;-2.42,-4.67,;-1.08,-3.9,;.25,-4.67,;-1.08,-2.36,;.25,-1.59,;.25,-.05,;.25,1.49,;.25,3.03,;-1.08,3.8,;-1.08,5.34,;.25,6.11,;.25,7.65,;1.58,5.34,;1.58,3.8,;2.92,3.03,;4.25,3.8,;5.59,3.03,;5.59,1.49,;4.25,.72,;3.93,-.78,;2.4,-.94,;1.77,.46,;2.92,1.49,;4.96,-1.93,;6.47,-1.61,;4.49,-3.39,;5.52,-4.54,;6.66,-3.51,;4.37,-5.57,;6.55,-5.68,;6.07,-7.15,;7.1,-8.29,;8.61,-7.97,;9.08,-6.51,;8.05,-5.36,;-2.42,-1.59,;-2.42,-.05,;-3.75,-2.36,;-5.08,-1.59,;-5.08,-.05,;-5.08,1.49,)|

BDBM546223

CCN(C1CCN(CC1)[C@H]1C[C@H](F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:9.9,wD:11.12,(-8.44,-3.4,;-7.11,-4.17,;-5.78,-3.4,;-5.78,-1.86,;-7.11,-1.09,;-7.11,.45,;-5.78,1.22,;-4.44,.45,;-4.44,-1.09,;-5.78,2.76,;-6.87,3.85,;-5.78,4.94,;-5.78,6.48,;-4.69,3.85,;-4.44,-4.17,;-4.44,-5.71,;-3.11,-6.48,;-1.78,-5.71,;-.44,-6.48,;.89,-5.71,;2.23,-6.48,;.89,-4.17,;2.23,-3.4,;2.23,-1.86,;2.23,-.32,;2.23,1.22,;.89,1.99,;.89,3.53,;2.23,4.3,;2.23,5.84,;3.56,3.53,;3.56,1.99,;4.89,1.22,;6.23,1.99,;7.56,1.22,;7.56,-.32,;6.23,-1.09,;5.91,-2.6,;4.38,-2.76,;3.75,-1.35,;4.89,-.32,;6.94,-3.74,;6.46,-5.2,;8.44,-3.42,;-.44,-3.4,;-.44,-1.86,;-1.78,-4.17,;-3.11,-3.4,;-3.11,-1.86,;-3.11,-.32,)|

BDBM546224

CCS(=O)(=O)NC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cnc(N(C)C3CCN(CC3)C3CC(F)(F)C3)c(C#N)c2c1=O

BDBM546225

CC(C)S(=O)(=O)NC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1C#CCn1c(C)nc2cnc(N(C)C3CCN(CC3)C3CC(F)(F)C3)c(C#N)c2c1=O

BDBM546226

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3CC3)c(=O)c2c1C#N

BDBM546227

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3CCC3)c(=O)c2c1C#N

BDBM546228

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3COC3)c(=O)c2c1C#N

BDBM546229

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C(C)(C)C)c(=O)c2c1C#N

BDBM546230

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CF)c(=O)c2c1C#N

BDBM546231

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C(F)(F)F)c(=O)c2c1C#N

BDBM546232

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC(F)F)c(=O)c2c1C#N

BDBM546233

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC(F)(F)F)c(=O)c2c1C#N

BDBM546234

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC#N)c(=O)c2c1C#N

BDBM546235

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CCC#N)c(=O)c2c1C#N

BDBM546236

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)CC(C)(C)C#N)c(=O)c2c1C#N

BDBM546240

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)Cc3ccccn3)c(=O)c2c1C#N

BDBM546241

CN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C3CC(F)(F)C3)c(=O)c2c1C#N

BDBM546242

CCN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccncc3)c(=O)c2c1C#N

BDBM546243

CCN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3cccnc3)c(=O)c2c1C#N

BDBM546244

CCN(C1CCN(CC1)C1CC(F)(F)C1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)c3ccccn3)c(=O)c2c1C#N

BDBM546245

CN(CC(F)F)[C@H]1CC[C@@H](CC1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:6.5,wD:9.12,(-4.44,3.85,;-5.78,3.08,;-7.11,3.85,;-7.11,5.39,;-8.44,6.16,;-5.78,6.16,;-5.78,1.54,;-4.44,.77,;-4.44,-.77,;-5.78,-1.54,;-7.11,-.77,;-7.11,.77,;-5.78,-3.08,;-7.11,-3.85,;-4.44,-3.85,;-4.44,-5.39,;-3.11,-6.16,;-1.78,-5.39,;-.44,-6.16,;.89,-5.39,;2.23,-6.16,;.89,-3.85,;2.23,-3.08,;2.23,-1.54,;2.23,,;2.23,1.54,;.89,2.31,;.89,3.85,;2.23,4.62,;2.23,6.16,;3.56,3.85,;3.56,2.31,;4.89,1.54,;6.23,2.31,;7.56,1.54,;7.56,,;6.23,-.77,;5.91,-2.28,;4.38,-2.44,;3.75,-1.03,;4.89,,;6.94,-3.42,;6.46,-4.89,;8.44,-3.1,;-.44,-3.08,;-.44,-1.54,;-1.78,-3.85,;-3.11,-3.08,;-3.11,-1.54,;-3.11,,)|

BDBM546246

CN(CC(F)F)[C@H]1CC[C@H](CC1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r,wU:6.5,9.12,(-4.44,3.85,;-5.78,3.08,;-7.11,3.85,;-7.11,5.39,;-8.44,6.16,;-5.78,6.16,;-5.78,1.54,;-4.44,.77,;-4.44,-.77,;-5.78,-1.54,;-7.11,-.77,;-7.11,.77,;-5.78,-3.08,;-7.11,-3.85,;-4.44,-3.85,;-4.44,-5.39,;-3.11,-6.16,;-1.78,-5.39,;-.44,-6.16,;.89,-5.39,;2.23,-6.16,;.89,-3.85,;2.23,-3.08,;2.23,-1.54,;2.23,,;2.23,1.54,;.89,2.31,;.89,3.85,;2.23,4.62,;2.23,6.16,;3.56,3.85,;3.56,2.31,;4.89,1.54,;6.23,2.31,;7.56,1.54,;7.56,,;6.23,-.77,;5.91,-2.28,;4.38,-2.44,;3.75,-1.03,;4.89,,;6.94,-3.42,;6.46,-4.89,;8.44,-3.1,;-.44,-3.08,;-.44,-1.54,;-1.78,-3.85,;-3.11,-3.08,;-3.11,-1.54,;-3.11,,)|

BDBM546247

CN(CC(F)F)[C@H]1CC[C@H](C1)N(C)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N |r|

BDBM546248

CN(C\C=C\c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N)CC(F)(F)F

BDBM546250

COC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM546252

CC(C)c1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM546253

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1cc(F)c(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM546254

Cc1nc2cc(c(Cl)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM546255

COC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(Cl)c(C#N)c2c1=O)C(F)(F)F

BDBM546256

COC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(c(CN(C)C)c(C#N)c2c1=O)C(F)(F)F

BDBM546257

CN1CCC(Cc2c(cc3nc(C)n(CCOc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)C(F)(F)F)C(=O)C1

BDBM546258

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(-c4ccc(F)c(C)n4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM546259

Cc1ccc(cn1)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM546260

CCc1ncc(cc1F)-c1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c(=O)c2c1C#N)C(F)(F)F

BDBM546261

Cc1nc2cc(c(N3CCC4(CN(CC(F)F)C4)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM546262

Cc1nc2cc(c(N3CCC4(CN(CC(F)F)C4)CC3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O)C(F)(F)F

BDBM546263

Cc1nc2cc(c(N3CC4(CN(C4)C4CC4)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O)C(F)(F)F

BDBM546264

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CC5(CN(C5)C5CC5)C4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM546265

CCc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(N4CC5(CN(C5)C5CC5)C4)c(C#N)c3c2=O)C(F)(F)F)c2scc(C(=O)NS(C)(=O)=O)c2n1

BDBM546266

CN1CCN(CC1)c1c(C#N)c2c(nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(C(O)=O)c(C)sc34)c2=O)c(C)c1C(F)(F)F

BDBM546267

CN1CCN(CC1)c1c(C#N)c2c(nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c2=O)c(C)c1C(F)(F)F

BDBM546268

Cc1nc2ccc(c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM546269

CN(C)Cc1ccc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546270

Cc1nc2cc(F)cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546271

OC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(nc2cc(F)cc(C#N)c2c1=O)C(F)F

BDBM546272

Cc1nc2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)F

BDBM546273

Cc1nc2cc(OC(F)F)cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546274

OC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(nc2c(F)ccc(C#N)c2c1=O)C(F)F

BDBM546275

Cc1nc2c(Cl)ccc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546276

OC(=O)c1csc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(nc2c(ccc(C#N)c2c1=O)C#N)C(F)F

BDBM546278

Cc1nc2c(F)cc(C(F)F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(=O)NS(C)(=O)=O

BDBM546279

Cc1nc2c3ccccc3cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546280

Cc1nc2cc(F)c(F)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546281

CN(C)S(=O)(=O)c1cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c(C#N)c1Cl

BDBM546282

Cc1nc2cc(Cl)c(C#N)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O

BDBM546283

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CC5(CCC5)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

BDBM546285

CN1Cc2cc3nc(C)n(CCOc4ccc(Cl)cc4-c4ccnc5c(csc45)C(O)=O)c(=O)c3c(C#N)c2S1(=O)=O

BDBM546286

CN1CCc2cc3nc(C)n(CCOc4ccc(Cl)cc4-c4ccnc5c(csc45)C(O)=O)c(=O)c3c(C#N)c2S1(=O)=O

BDBM546287

CN(C)Cc1cc2c(nc(C)n(CCOc3ccc(Cl)cc3-c3cc(C)nc4c(csc34)C(O)=O)c2=O)c(C)n1

BDBM546288

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)OC(C)(C)C)c(=O)c2c1C(N)=O

BDBM546289

CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C(N)=O

BDBM546290

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(ncc(Cl)c3c2=O)C2CC2)c2scc(C(O)=O)c2n1

BDBM546291

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(nc(C4CC4)c(C)c3c2=O)C#N)c2scc(C(O)=O)c2n1

BDBM546292

Cc1nc2c(nc(CC3CCOCC3)c(C)c2c(=O)n1CC#Cc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C#N

BDBM546294

CN1CCC(CC1)c1cc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(C(O)=O)c(C)sc13)c2=O

BDBM546295

Cc1nc2cc(c3COC(=O)c3c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM546296

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(nc2cccc(C#N)c2c1=O)C(F)F

BDBM546297

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c4CCC(=O)c4c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM546298

Cc1cc(-c2cc(Cl)ccc2OCCn2c(=O)n(C)c3cc(cc(C#N)c3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM546299

Cc1cc2cc(cc(C#N)c2c(O)c1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F

BDBM546300

COc1c(CCOc2ccc(Cl)cc2-c2ccnc3c(csc23)C(O)=O)c(C)cc2cc(cc(C#N)c12)C(F)(F)F

BDBM546301

Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(c(Cl)nc3c2=O)C(F)(F)F)c2scc(C(O)=O)c2n1

BDBM546302

CN1CCN(CC1)c1cc(c2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2n1)C(F)(F)F

BDBM546303

Cc1nc2cncc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O

BDBM546304

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(nc2cncc(C#N)c2c1=O)C(F)F

BDBM546306

CCC#Cc1c(cccc1-c1cc(Cl)ccc1OCCn1c(nc2cccc(C#N)c2c1=O)C(F)F)C(O)=O

BDBM546307

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1cnc2cc(Br)cc(C#N)c2c1=O

BDBM546308

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1cnc2cc(cc(C#N)c2c1=O)C#N

BDBM546309

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1cnc2c(ccc(C#N)c2c1=O)C#N

BDBM546310

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1nnc2ccccc2c1=O

BDBM546311

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1cnc2cnccc2c1=O

BDBM546312

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1cnc2c(nccc2c1=O)C(F)(F)F

BDBM546313

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1cnc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM546314

Cc1nc2cnc(cc2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)C#N

BDBM546315

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(nc2cnc(cc2c1=O)C#N)C(F)F

BDBM546316

Cc1nc2c(nc(cc2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)C#N)C#N

BDBM546317

Cc1nc2cnc(CN)cc2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O

BDBM546318

Cc1nc2cncc(Br)c2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O

BDBM546319

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(Nc2ccccc2)nc2c(O)nccc2c1=O

BDBM546320

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(Nc2ccccc2)nc2c(Cl)nccc2c1=O

BDBM546321

Cc1nc2cnc(Nc3cc(F)cc(F)c3)cc2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O

BDBM546322

Cc1nc2cnc(NC3CCCCC3)cc2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O

BDBM546323

Cc1nc2cnc(Nc3ccccc3)cc2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O

BDBM546324

Cc1nc2cnc(NC3CCCC3)cc2c(=O)n1CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O

BDBM546325

CNc1cc2c(cn1)nc(C)n(CCOc1ccc(Cl)cc1-c1cccc(c1)C(O)=O)c2=O

BDBM546326

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(nc2cnc(Cl)cc2c1=O)C(F)(F)F

BDBM546327

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(nc2cnc(Cl)cc2c1=O)C(F)F

BDBM546328

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(nc2cccc(Br)c2c1=O)C(F)F

BDBM546329

OC(=O)c1cccc(c1)-c1cc(Cl)ccc1OCCn1c(nc2cncc(Br)c2c1=O)C(F)F

BDBM546330

CN1Cc2ccc3nc(C)n(CCOc4ccc(Cl)cc4-c4cccc(c4)C(O)=O)c(=O)c3c2C1=O

BDBM546331

OC(=O)c1cc-2ccc1CCCCCc1nc3cc(cc(Br)c3c(=O)n1CCOc1ccc(Cl)cc-21)C(F)(F)F

BDBM546332

OC(=O)c1cc(ccn1)-c1cc(Cl)ccc1OCCn1nnc2ccccc2c1=O

BDBM546333

Cc1nc2cc(c(N3CC4(CN(C4)C4CC4)C3)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2ccsc12)C(F)(F)F

BDBM546334

CN(C)Cc1c(cc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4ccsc34)c(=O)c2c1C#N)C(F)(F)F

BDBM546335

OC(=O)c1csc2c(cccc12)-c1cc(Cl)ccc1OCCn1c(nc2cccc(C#N)c2c1=O)C(F)F

BDBM546337

COC(=O)c1ccc2c(cc[nH]c12)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(cc(C#N)c2c1=O)C(F)(F)F

BDBM546338

CN1CCN(C2CC12)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3cccc4c(csc34)C(O)=O)c(=O)c2c1C#N

BDBM546339

OC(=O)c1cccc(c1)-c1cc(ccc1OCCn1cnc2cnc(cc2c1=O)C#N)C#N

BDBM546340

CN1CCN(Cc2ccc(OCCn3c(C)nc4cc(F)c(CN5CCN(C)CC5)c(C#N)c4c3=O)c(c2)-c2cc(C)nc3c(csc23)C(O)=O)CC1

BDBM546342

OC(=O)c1scc(c1C#C)-c1cc(Cl)ccc1OCCn1c(nc2cccc(C#N)c2c1=O)C(F)F

BDBM546343

OC(=O)c1scc2c(ccnc12)-c1cc(Cl)ccc1OCCn1c(nc2cccc(C#N)c2c1=O)C(F)F

BDBM546344

Cc1cc(-c2cc(ccc2OCCn2c(C)nc3cc(c(N4CC(F)(F)C4)c(C#N)c3c2=O)C(F)(F)F)N2CC(F)(F)C2)c2scc(C(O)=O)c2n1

BDBM546345

COC(=O)c1sc2c(ccnc2c1O)-c1cc(Cl)ccc1OCCn1c(C)nc2cc(cc(C#N)c2c1=O)C(F)(F)F