Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'cGMP-dependent protein kinase 2 [41-418,G356E]'
TargetcGMP-dependent protein kinase 2 [41-418,G356E](Human)
Baylor College of Medicine

LigandPNGBDBM65501(Cyclic GMP analogs | 8-pCP-cGMP | cGMP)
Affinity DataEC50:  50nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-dependent protein kinase 2 [41-418,G356E](Human)
Baylor College of Medicine

LigandPNGBDBM65502(2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...)
Affinity DataEC50:  30nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-dependent protein kinase 2 [41-418,G356E](Human)
Baylor College of Medicine

LigandPNGBDBM65501(Cyclic GMP analogs | 8-pCP-cGMP | cGMP)
Affinity DataEC50: <1nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-dependent protein kinase 2 [41-418,G356E](Human)
Baylor College of Medicine

LigandPNGBDBM65505(PET-cGMP)
Affinity DataEC50:  5.30nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed