Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with Target = 'cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1'
LigandPNGBDBM50025356(4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...)
Affinity DataIC50: 1.30nMpH: 6.5 T: 2°CAssay Description:The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
LigandPNGBDBM235657(4-Bromo-17α-hydroxypregn-4-ene-3,20-dione (7b...)
Affinity DataIC50: 1.60nMpH: 6.5 T: 2°CAssay Description:The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
LigandPNGBDBM235655(17α-Hydroxypregn-4-ene-3,20-dione (5))
Affinity DataIC50: 2nMpH: 6.5 T: 2°CAssay Description:The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
LigandPNGBDBM233039(Finasteride (3))
Affinity DataIC50: 8.5nMpH: 6.5 T: 2°CAssay Description:The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
LigandPNGBDBM233040(17α-Acetoxyprogesterone (6))
Affinity DataIC50: 10nMpH: 6.5 T: 2°CAssay Description:The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
LigandPNGBDBM233043(6-Chloro-3,20-dioxopregna-4,6-diene-17α-yl ac...)
Affinity DataIC50: 19nMpH: 6.5 T: 2°CAssay Description:The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
LigandPNGBDBM233042(3,20-Dioxo-6,7-epoxypregn-4-ene-7α-yl acetate...)
Affinity DataIC50: 22nMpH: 6.5 T: 2°CAssay Description:The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
LigandPNGBDBM235659(4-Bromo-3,20-dioxopregn-4-ene-17-yl-4-ethylbenzoat...)
Affinity DataIC50: 50nMpH: 6.5 T: 2°CAssay Description:The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
LigandPNGBDBM235656(4-Chloro-17α-hydroxypregn-4-ene-3,20-dione (7...)
Affinity DataIC50: 63nMpH: 6.5 T: 2°CAssay Description:The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
LigandPNGBDBM233041(3,20-Dioxopregna-4,6-dien-17α-yl acetate (7))
Affinity DataIC50: 70nMpH: 6.5 T: 2°CAssay Description:The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
LigandPNGBDBM235658(4-Chloro-3,20-dioxopregn-4-ene-17-yl-4-ethylbenzoa...)
Affinity DataIC50: 73nMpH: 6.5 T: 2°CAssay Description:The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
LigandPNGBDBM235654(3,20-Dioxopregn-4-ene-17-yl acetate (4))
Affinity DataIC50: 500nMpH: 6.5 T: 2°CAssay Description:The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed