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Report error Found 44 Enz. Inhib. hit(s) with Target = 'YEATS domain-containing protein 4'
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616146(CHEMBL5411016)
Affinity DataKd:  530nMAssay Description:Binding affinity to C-terminal biotin-tagged YEATS4 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616147(CHEMBL5434894)
Affinity DataKd:  45nMAssay Description:Binding affinity to YEATS4 (unknown origin) assessed as dissociation constant by isothermal calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616151(CHEMBL5397585)
Affinity DataKd:  53nMAssay Description:Binding affinity to YEATS4 (unknown origin) assessed as dissociation constant by isothermal calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616146(CHEMBL5411016)
Affinity DataKd:  80nMAssay Description:Binding affinity to YEATS4 (unknown origin) assessed as dissociation constant by isothermal calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616142(CHEMBL5428051)
Affinity DataKd:  340nMAssay Description:Binding affinity to C-terminal biotin-tagged YEATS4 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616151(CHEMBL5397585)
Affinity DataKd:  103nMAssay Description:Binding affinity to C-terminal biotin-tagged YEATS4 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616147(CHEMBL5434894)
Affinity DataKd:  297nMAssay Description:Binding affinity to C-terminal biotin-tagged YEATS4 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616142(CHEMBL5428051)
Affinity DataKd:  53nMAssay Description:Binding affinity to YEATS4 (unknown origin) assessed as dissociation constant by isothermal calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616152(CHEMBL5439842)
Affinity DataKd:  30nMAssay Description:Binding affinity to YEATS4 (unknown origin) assessed as dissociation constant by isothermal calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50631859(CHEMBL5409682)
Affinity DataIC50: 96nMAssay Description:Inhibition of human N-terminal GST tagged GAS41 (1 to 148 residues) incubated for 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616142(CHEMBL5428051)
Affinity DataIC50: 170nMAssay Description:Inhibition of N-terminal nanoLuc-tagged YEATS4 in HEK293T cells co-transfected with C-terminal halo-tagged histone 3.3 incubated for 24 hrs in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616151(CHEMBL5397585)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal nanoLuc-tagged YEATS4 in HEK293T cells co-transfected with C-terminal halo-tagged histone 3.3 incubated for 24 hrs in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616146(CHEMBL5411016)
Affinity DataIC50: 290nMAssay Description:Inhibition of N-terminal nanoLuc-tagged YEATS4 in HEK293T cells co-transfected with C-terminal halo-tagged histone 3.3 incubated for 24 hrs in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616152(CHEMBL5439842)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal nanoLuc-tagged YEATS4 in HEK293T cells co-transfected with C-terminal halo-tagged histone 3.3 incubated for 24 hrs in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616147(CHEMBL5434894)
Affinity DataIC50: 730nMAssay Description:Inhibition of N-terminal nanoLuc-tagged YEATS4 in HEK293T cells co-transfected with C-terminal halo-tagged histone 3.3 incubated for 24 hrs in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50625616(CHEMBL5398308)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of YEATS4 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50625620(CHEMBL4762606)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of YEATS4 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of YEATS4 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50625618(CHEMBL5429859)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of YEATS4 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50625617(CHEMBL5421606)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of YEATS4 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50625615(CHEMBL5435042)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of YEATS4 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50625614(CHEMBL5427853)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of YEATS4 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50625613(CHEMBL5394670)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of YEATS4 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50625612(CHEMBL5416331)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of YEATS4 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50625604(CHEMBL5439680)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of YEATS4 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50566873(CHEMBL4859531)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human His-GAS41 YEATS domain and biotinylated H3K27ac peptide interaction by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50566867(CHEMBL4855926)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human His-GAS41 YEATS domain and biotinylated H3K27ac peptide interaction by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50566877(CHEMBL4863719)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human His-GAS41 YEATS domain and biotinylated H3K27ac peptide interaction by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50566890(CHEMBL4865432)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human His-GAS41 YEATS domain and biotinylated H3K27ac peptide interaction by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50631858(CHEMBL1573062)
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibition of human N-terminal GST tagged GAS41 (1 to 148 residues) incubated for 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616151(CHEMBL5397585)
Affinity DataKi:  21nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616142(CHEMBL5428051)
Affinity DataKi:  33nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616148(CHEMBL5414722)
Affinity DataKi:  33nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616152(CHEMBL5439842)
Affinity DataKi:  37nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616153(CHEMBL5432565)
Affinity DataKi:  43nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616149(CHEMBL5439506)
Affinity DataKi:  56nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616154(CHEMBL5426169)
Affinity DataKi:  57nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616147(CHEMBL5434894)
Affinity DataKi:  59nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616146(CHEMBL5411016)
Affinity DataKi:  63nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616150(CHEMBL5432083)
Affinity DataKi:  69nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616145(CHEMBL5429949)
Affinity DataKi:  141nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616144(CHEMBL5435884)
Affinity DataKi:  284nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616143(CHEMBL5439514)
Affinity DataKi:  540nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed