Compile Data Set for Download or QSAR
Report error Found 142 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK [342-635]'
TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311138(example 6.09 on page 559 of WO15017610)
Affinity DataIC50: 0.100nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311136(example 5.20 on page 506 of WO15017610)
Affinity DataIC50: 0.200nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140389(US8912173, 114 | US9914735, Example 114 | US109472...)
Affinity DataIC50: 0.200nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140390(US8912173, 115 | US9914735, Example 115 | US109472...)
Affinity DataIC50: 0.200nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375967(US9914735, Example 45 | US10947243, Example 45)
Affinity DataIC50: 0.200nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311139(example 3B.22 on page 219 of WO15017610)
Affinity DataIC50: 0.800nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311126(US10155751, Example 13)
Affinity DataIC50: 0.900nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311114(US10155751, Example 1)
Affinity DataIC50: 1nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375964(US9914735, Example 41 | US10947243, Example 41)
Affinity DataIC50: 1nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140369(US8912173, 94 | US9914735, Example 94 | US10947243...)
Affinity DataIC50: 1nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140380(US8912173, 105 | US9914735, Example 105 | US109472...)
Affinity DataIC50: 1nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140384(US8912173, 109 | US9914735, Example 109 | US109472...)
Affinity DataIC50: 1nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375960(US9914735, Example 35 | US10947243, Example 35)
Affinity DataIC50: 1nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375942(US9914735, Example 8 | US10947243, Example 8)
Affinity DataIC50: 1nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375942(US9914735, Example 8 | US10947243, Example 8)
Affinity DataIC50: 1nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375944(US9914735, Example 10 | US10947243, Example 10)
Affinity DataIC50: 1nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375966(US9914735, Example 43 | US10947243, Example 43)
Affinity DataIC50: 1nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311122(US10155751, Example 9)
Affinity DataIC50: 1.10nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311131(US10155751, Example 18)
Affinity DataIC50: 1.10nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311134(US10155751, Example 21)
Affinity DataIC50: 1.20nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311135(US10155751, Example 22)
Affinity DataIC50: 1.20nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311115(US10155751, Example 2)
Affinity DataIC50: 1.30nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311120(US10155751, Example 7)
Affinity DataIC50: 1.30nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311121(US10155751, Example 8)
Affinity DataIC50: 1.40nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311124(US10155751, Example 11)
Affinity DataIC50: 1.5nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311132(US10155751, Example 19)
Affinity DataIC50: 1.80nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311137(example 3A.02, on page 196 of WO15017610)
Affinity DataIC50: 1.90nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311116(US10155751, Example 3)
Affinity DataIC50: 2nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375957(US9914735, Example 29 | US10947243, Example 29)
Affinity DataIC50: 2nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375965(US9914735, Example 42 | US10947243, Example 42)
Affinity DataIC50: 2nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375982(US9914735, Example 61 | US10947243, Example 61)
Affinity DataIC50: 2nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140360(US8912173, 85 | US9914735, Example 85 | US10947243...)
Affinity DataIC50: 2nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375941(US9914735, Example 7 | US10947243, Example 7)
Affinity DataIC50: 2nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375945(US9914735, Example 11 | US10947243, Example 11)
Affinity DataIC50: 2nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375949(US9914735, Example 15 | US9914735, Example 76 | US...)
Affinity DataIC50: 2nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140376(US8912173, 101 | US9914735, Example 101 | US109472...)
Affinity DataIC50: 2nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311117(US10155751, Example 4)
Affinity DataIC50: 2.20nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311128(US10155751, Example 15)
Affinity DataIC50: 2.20nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311133(US10155751, Example 20)
Affinity DataIC50: 2.5nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311119(US10155751, Example 6)
Affinity DataIC50: 2.60nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311125(US10155751, Example 12)
Affinity DataIC50: 2.90nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311130(US10155751, Example 17)
Affinity DataIC50: 2.90nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM376002(US9914735, Example 81 | US10947243, Example 81)
Affinity DataIC50: 3nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM144453(US8969568, 4 | US9914735, Example 4 | US10947243, ...)
Affinity DataIC50: 3nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311129(US10155751, Example 16)
Affinity DataIC50: 3.10nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311127(US10155751, Example 14)
Affinity DataIC50: 3.20nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311118(US10155751, Example 5)
Affinity DataIC50: 3.30nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM311123(US10155751, Example 10)
Affinity DataIC50: 3.30nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140280(US8912173, 6 | US9914735, Example 6 | US10947243, ...)
Affinity DataIC50: 4nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie Dept. of Biochemistry) in 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK [342-635](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375952(US9914735, Example 18 | US10947243, Example 18)
Affinity DataIC50: 4.60nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

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