Compile Data Set for Download or QSAR
Report error Found 1477 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2 [828-1132]'
TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM197716(US9216984, 1)
Affinity DataIC50: 0.260nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2016
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM197716(US9216984, 1)
Affinity DataIC50: 0.290nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2016
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM197717(US9216984, 2)
Affinity DataIC50: 0.300nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2016
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM197717(US9216984, 2)
Affinity DataIC50: 0.650nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2016
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM197717(US9216984, 2)
Affinity DataIC50: 1.40nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM197716(US9216984, 1)
Affinity DataIC50: 2.20nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM400481(US9999619, Example 236 | US10695337, Example 236 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
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Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM400486({1-[8-(2-Chloro-3,6-difluorobenzyl)-8-azabicyclo[3...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
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Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400491(US9999619, Example 247 | US10695337, Example 247 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
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Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400495(US9999619, Example 251 | US10695337, Example 251 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
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Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400497(US9999619, Example 253 | US10695337, Example 253 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
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Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM400502(US9999619, Example 258 | US10695337, Example 258 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
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Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400503(US9999619, Example 259 | US10695337, Example 259 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400514(US9999619, Example 270 | US10695337, Example 270 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400517(US9999619, Example 273 | US10695337, Example 273)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
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Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM400520(US9999619, Example 276 | US10695337, Example 276 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM400522(US9999619, Example 278 | US10695337, Example 278 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400523(US9999619, Example 279 | US10695337, Example 279 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400524(US9999619, Example 280 | US10695337, Example 280 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400532(US9999619, Example 288 | US10695337, Example 288 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM400541(US9999619, Example 297 | US10695337, Example 297 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400566(US9999619, Example 322 | US10695337, Example 322 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400567(US9999619, Example 323 | US10695337, Example 323 |...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400579(US9999619, Example 335 | US11285140, Example 335)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400580(US9999619, Example 336 | US11285140, Example 336)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM400599({3-[4-(5-Fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400251(US9999619, Example 7 | US10695337, Example 6 | US1...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400263(US9999619, Example 19 | US10695337, Example 18 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400264(US9999619, Example 20 | US10695337, Example 19 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400268(US9999619, Example 24 | US10695337, Example 23 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400270(US9999619, Example 26 | US10695337, Example 25 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400272(US9999619, Example 28 | US10695337, Example 27 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400273(US9999619, Example 29 | US10695337, Example 28 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400274(US9999619, Example 30 | US10695337, Example 29 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400275(US9999619, Example 31 | US10695337, Example 30 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400277(US9999619, Example 33 | US10695337, Example 32 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400280(US9999619, Example 36 | US10695337, Example 35 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400281(US9999619, Example 37 | US10695337, Example 36 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400282(US9999619, Example 38 | US10695337, Example 37 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400283(US9999619, Example 39 | US10695337, Example 38 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400285(US9999619, Example 40 | US10695337, Example 39 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400286(US9999619, Example 41 | US10695337, Example 40 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400287(US9999619, Example 42 | US10695337, Example 41 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400289(US9999619, Example 44 | US10695337, Example 43 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400292(US9999619, Example 47 | US10695337, Example 46 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400294(US9999619, Example 49 | US10695337, Example 48 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400295(US9999619, Example 50 | US10695337, Example 49 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400296(US9999619, Example 51 | US10695337, Example 50 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400301(US9999619, Example 56 | US10695337, Example 55 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM400304(US9999619, Example 59 | US10695337, Example 58 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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