Compile Data Set for Download or QSAR
Report error Found 1745 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1 [837-1142]'
TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM701120(US20240343747, Example B2)
Affinity DataKd: >3.00E+4nMAssay Description:The lysates were centrifuged and filtered to remove cell debris. The remaining kinases were produced in HEK-293 cells and subsequently tagged with DN...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM701121(US20240343747, Example B3)
Affinity DataKd: >3.00E+4nMAssay Description:The lysates were centrifuged and filtered to remove cell debris. The remaining kinases were produced in HEK-293 cells and subsequently tagged with DN...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM701122(US20240343747, Example B4)
Affinity DataKd: >3.00E+4nMAssay Description:The lysates were centrifuged and filtered to remove cell debris. The remaining kinases were produced in HEK-293 cells and subsequently tagged with DN...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM701123(US20240343747, Example B5)
Affinity DataKd: >3.00E+4nMAssay Description:The lysates were centrifuged and filtered to remove cell debris. The remaining kinases were produced in HEK-293 cells and subsequently tagged with DN...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM701124(US20240343747, Example B11)
Affinity DataKd: >3.00E+4nMAssay Description:The lysates were centrifuged and filtered to remove cell debris. The remaining kinases were produced in HEK-293 cells and subsequently tagged with DN...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM701133(US20240343747, Example B37)
Affinity DataKd: >3.00E+4nMAssay Description:The lysates were centrifuged and filtered to remove cell debris. The remaining kinases were produced in HEK-293 cells and subsequently tagged with DN...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM701134(US20240343747, Example B38)
Affinity DataKd: >3.00E+4nMAssay Description:The lysates were centrifuged and filtered to remove cell debris. The remaining kinases were produced in HEK-293 cells and subsequently tagged with DN...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM701136(US20240343747, Example B41)
Affinity DataKd: >3.00E+4nMAssay Description:The lysates were centrifuged and filtered to remove cell debris. The remaining kinases were produced in HEK-293 cells and subsequently tagged with DN...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM197716(US9216984, 1)
Affinity DataIC50: 0.340nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM197717(US9216984, 2)
Affinity DataIC50: 0.570nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM197716(US9216984, 1)
Affinity DataIC50: 0.630nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM197717(US9216984, 2)
Affinity DataIC50: 1.80nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM197717(US9216984, 2)
Affinity DataIC50: 2nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM197716(US9216984, 1)
Affinity DataIC50: 3.90nMpH: 7.8 T: 2°CAssay Description:The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400612({1-{1-[6-[(dimethylamino)methyl]-3-fluoro-2-(trifl...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM448803(US10695337, Example 369 | 3-[(4-{3-(cyanomethyl)-3...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400614({1-(1-{[6-[(dimethylamino)methyl]-2-(trifluorometh...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400615({1-(1-{[6-[(methylamino)methyl]-2-(trifluoromethyl...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400616({1-(1-{[6-(azetidin-1-ylmethyl)-2-(trifluoromethyl...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400617({1-(1-{[6-[(diethylamino)methyl]-2-(trifluoromethy...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400618({1-(1-{[6-{[ethyl(methyl)amino]methyl}-2-(trifluor...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400619({1-(1-{3-(difluoromethyl)-5-[(dimethylamino)methyl...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400620({1-(1-{[6-(pyrrolidin-1-ylmethyl)-2-(trifluorometh...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400621({1-(1-{[6-{[(3S)-3-fluoropyrrolidin-1-yl]methyl}-2...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400622({1-(1-{[6-{[(3R)-3-fluoropyrrolidin-1-yl]methyl}-2...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400623({1-(1-{[6-[(3,3-difluoropyrrolidin-1-yl)methyl]-2-...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400624({1-(1-{[6-[(tert-butylamino)methyl]-2-(trifluorome...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400625({1-(1-{[6-(hydroxymethyl)-2-(trifluoromethyl)pyrim...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400626({1-(1-{[6-[(isopropylamino)methyl]-2-(trifluoromet...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400627({1-(1-{[6-[(ethylamino)methyl]-2-(trifluoromethyl)...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400628({1-(1-{[6-{[(2-methoxyethyl)(methyl)amino]methyl}-...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400629({1-(1-{[6-{[(3-hydroxypropyl)(methyl)amino]methyl}...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400630(Propyl 4-{3-(cyanomethyl)-3-[4-(7H-pyrrolo[2,3-d]p...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400631(Cyclobutylmethyl 4-{3-(cyanomethyl)-3-[4-(7H-pyrro...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400633(benzyl 4-{3- (cyanomethyl)-3-[4-(7H- pyrrolo[2,3-d...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400634(isobutyl 4-{3- (cyanomethyl)-3-[4-(7H- pyrrolo[2,3...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400637(2,4-difluorobenzyl 4-{3- (cyanomethyl)-3-[4-(7H- p...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400639(3,5-difluorobenzyl 4-{3- (cyanomethyl)-3-[4-(7H- p...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400640(cyclopentylmethyl 4-{3- (cyanomethyl)-3-[4-(7H- py...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400641(US9999619, Example 397 | US10695337, Example 397 |...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM246868({1-{1-[3-Fluoro-2- (trifluoromethyl) isonicotinoyl...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400244({1-[1-(3-Fluoro-4-quinolin-6-ylbenzoyl)piperidin-4...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400247(US9999619, Example 3 | US9999619, Example 4 | US10...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400250(US9999619, Example 6 | US10695337, Example 5 | US1...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400251(US9999619, Example 7 | US10695337, Example 6 | US1...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400252(US9999619, Example 8 | US10695337, Example 7 | US1...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400254(US9999619, Example 10 | US10695337, Example 9 | US...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400258(US9999619, Example 14 | US10695337, Example 13 | U...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400264(US9999619, Example 20 | US10695337, Example 19 | U...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM400265(US9999619, Example 21 | US10695337, Example 20 | U...)
Affinity DataIC50: 5nMAssay Description:The catalytic domains of human JAK1 (a.a. 837-1142), Jak2 (a.a. 828-1132) and Jak3 (a.a. 781-1124) with an N-terminal His tag were expressed using ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

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