Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with Target = 'Tubulin beta-1 chain'
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152133(4-{[3,3-Dimethyl-2-(3-methyl-2-methylamino-3-pheny...)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152123(4-({2-[3-(4-Methoxy-phenyl)-3-methyl-2-methylamino...)
Affinity DataKd:  700nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152118(4-[(2-{2-[(2-Hydroxy-ethyl)-methyl-amino]-3-methyl...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152105(Ethyl-(S)-N,beta,beta-Trimethylphenylalanyl-(S)-te...)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152135(4-{[2-(3-Cyclohexyl-3-methyl-2-methylamino-butyryl...)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150585(2,5-Dimethyl-4-{methyl-[3-methyl-2-(3-methyl-2-met...)
Affinity DataKd:  700nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150589(CHEMBL182319 | 4-{[3,3-Dimethyl-2-(3-methyl-2-meth...)
Affinity DataKd:  260nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159307(2-Methoxy-5-[(Z)-2-(3,4,5-trimethyl-phenyl)-vinyl]...)
Affinity DataIC50: 120nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159294(2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-prope...)
Affinity DataIC50: 130nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159292(2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-but-1...)
Affinity DataIC50: 130nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 180nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50: 200nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159295((E)-3-(3-Hydroxy-4-methoxy-phenyl)-1-(2,3,4-trimet...)
Affinity DataIC50: 450nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50070107((E)-3-(3''-Hydroxy-4''-methoxyphenyl)-2-methyl-1-(...)
Affinity DataIC50: 460nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159301((Z)-3-(3-Fluoro-4-methoxy-phenyl)-2-methoxy-1-(3,4...)
Affinity DataIC50: 470nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159305(2-Methoxy-5-[(Z)-2-(3,4,5-triethoxy-phenyl)-vinyl]...)
Affinity DataIC50: 500nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159313((Z)-3-(3-Hydroxy-4-methoxy-phenyl)-2-methoxy-1-(3,...)
Affinity DataIC50: 510nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50095321(2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-benzaldeh...)
Affinity DataIC50: 560nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50070104(3-hydroxy-3',4,4',5'-tetramethoxychalcone | (2E)-3...)
Affinity DataIC50: 620nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159300((E)-3-(3-Fluoro-4-methoxy-phenyl)-2-methyl-1-(3,4,...)
Affinity DataIC50: 650nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159290(5-[(Z)-2-(4-Methoxy-phenyl)-vinyl]-1,2,3-trimethyl...)
Affinity DataIC50: 650nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159311(5-[(Z)-2-(3-Fluoro-4-methoxy-phenyl)-vinyl]-1,2,3-...)
Affinity DataIC50: 700nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50151097((6-Methoxy-2-methyl-1H-indol-3-yl)-(3,4,5-trimetho...)
Affinity DataIC50: 900nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50168445(5-[(Z)-2-(3-Bromo-4-methoxy-phenyl)-vinyl]-1,2,3-t...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159306(1,2,3-Triethoxy-5-[(Z)-2-(3-fluoro-4-methoxy-pheny...)
Affinity DataIC50: 1.20E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159297((E)-3-(3-Fluoro-4-methoxy-phenyl)-1-(3,4,5-trimeth...)
Affinity DataIC50: 1.20E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159298(5-[(Z)-2-(3-Fluoro-4-methoxy-phenyl)-vinyl]-2,3-di...)
Affinity DataIC50: 1.25E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159309(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-1-met...)
Affinity DataIC50: 1.30E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50064482(N-(2-Hydroxy-1,3-dimethoxy-10-methylsulfanyl-9-oxo...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against tubulin assemblyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159312((Z)-3-(3'',5''-Difluoro-4''-methoxyphenyl)-2-metho...)
Affinity DataIC50: 1.70E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159296(5-[(Z)-2-(3,4-Dimethyl-phenyl)-vinyl]-1,2,3-trimet...)
Affinity DataIC50: 2.00E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159318((E)-3-(3-amino-4-methoxyphenyl)-1-(3,4,5-trimethox...)
Affinity DataIC50: 2.00E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50151101((6-methoxy-1H-indol-3-yl)(3,4,5-trimethoxyphenyl)m...)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159317((E)-3-(3'',5''-Difluoro-4''-methoxyphenyl)-2-methy...)
Affinity DataIC50: 2.40E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159316(2-Methoxy-5-((Z)-styryl)-phenol | CHEMBL364969)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50168443(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-3-nitro-pheny...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50151100((3,5-Dimethoxy-phenyl)-(6-methoxy-1H-indol-3-yl)-m...)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50168446(2-{2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vi...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157477(N-((S)-10-Hydroxy-1,2,3-trimethoxy-9-oxo-5,6,7,9-t...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitory concentration against tubulin assemblyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159310(5-[(Z)-2-(3,4-Dimethyl-phenyl)-vinyl]-2-methoxy-ph...)
Affinity DataIC50: 3.10E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50151098((5-Methoxy-2-methyl-indol-1-yl)-(3,4,5-trimethoxy-...)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50006675(5-[2-(4-Ethyl-phenyl)-vinyl]-1,2,3-trimethoxy-benz...)
Affinity DataIC50: 3.40E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50151115((5-Methoxy-indol-1-yl)-(3,4,5-trimethoxy-phenyl)-m...)
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157478(CHEMBL180503 | CHEMBL180388 | Dimethylamino-acetic...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory concentration against tubulin assemblyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159302(3-(3''-Hydroxy-4''-methoxyphenyl)-2-methyl-1-(3',4...)
Affinity DataIC50: 4.00E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159304((Z)-2-methoxy-5-(3,4,5-trifluorostyryl)phenol | 2-...)
Affinity DataIC50: 4.50E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157479(N-(2-Hydroxy-1,3,10-trimethoxy-9-oxo-5,6,7,9-tetra...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibitory concentration against tubulin assemblyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159299(1,2,3-Trifluoro-5-[(Z)-2-(3-fluoro-4-methoxy-pheny...)
Affinity DataIC50: 5.50E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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