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Report error Found 12 Enz. Inhib. hit(s) with Target = 'Transforming growth factor beta-1 proprotein'
TargetTransforming growth factor beta-1 proprotein(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50353187(CHEMBL1829511)
Affinity DataIC50: 11nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTransforming growth factor beta-1 proprotein(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50015639(CHEMBL3260567 | USRE47141, Example 2)
Affinity DataIC50: 13nMAssay Description:Inhibition of TGF-beta receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTransforming growth factor beta-1 proprotein(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50184879(dimethyl-{2-[(4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTransforming growth factor beta-1 proprotein(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50353188(CHEMBL1829512)
Affinity DataIC50: 32nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTransforming growth factor beta-1 proprotein(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50610513(CHEMBL5280211)
Affinity DataIC50: 38nMAssay Description:Inhibition of TGF-beta receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTransforming growth factor beta-1 proprotein(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50610512(CHEMBL5272606)
Affinity DataIC50: 56nMAssay Description:Inhibition of TGF-beta receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTransforming growth factor beta-1 proprotein(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50353184(CHEMBL1828640)
Affinity DataIC50: 68nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTransforming growth factor beta-1 proprotein(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50353185(CHEMBL1829504)
Affinity DataIC50: 77nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTransforming growth factor beta-1 proprotein(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50353186(CHEMBL1829505)
Affinity DataIC50: 88nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTransforming growth factor beta-1 proprotein(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50184872(4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-...)
Affinity DataIC50: 446nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTransforming growth factor beta-1 proprotein(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50585028(CHEMBL5078185)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of TGF beta 1 (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetTransforming growth factor beta-1 proprotein(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50525413(CHEMBL4448117)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of TGF beta 1 (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed