Compile Data Set for Download or QSAR
Report error Found 592 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 2'
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358537(CHEMBL1923536)
Affinity DataEC50:  0.450nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358538(CHEMBL1923537)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358539(CHEMBL1923538)
Affinity DataEC50:  0.870nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358540(CHEMBL1923539)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358541(CHEMBL1923540)
Affinity DataEC50:  6.48nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358542(CHEMBL1923541)
Affinity DataEC50:  0.560nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358543(CHEMBL1923542)
Affinity DataEC50:  1.47nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358544(CHEMBL1923543)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358545(CHEMBL1923544)
Affinity DataEC50:  2.11nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358546(CHEMBL1923545)
Affinity DataEC50:  1.55nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358547(CHEMBL1923546)
Affinity DataEC50:  3.23nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358548(CHEMBL1923547)
Affinity DataEC50:  1.95nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358549(CHEMBL1923548)
Affinity DataEC50:  1.86nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358550(CHEMBL1923549 | US9676818, 6d)
Affinity DataEC50:  4.44nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358551(CHEMBL1923550)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358552(CHEMBL1923551)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358553(CHEMBL1923552)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358554(CHEMBL1923553)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358555(CHEMBL1923554)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358556(CHEMBL1923555)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358557(CHEMBL1923556)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358558(CHEMBL1923557)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50399450(CHEMBL2179403)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50399451(CHEMBL2179404)
Affinity DataEC50:  78nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50399452(CHEMBL2179778)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50399453(CHEMBL2179779)
Affinity DataEC50:  56nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50399456(CHEMBL2179399)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50399457(CHEMBL2179400)
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50399454(CHEMBL2179401)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50399455(CHEMBL2179402)
Affinity DataEC50:  39nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50386534(CHEMBL2048075 | US9676818, 11d)
Affinity DataEC50:  1.01nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50386535(CHEMBL2048219 | US9676818, 11h)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358550(CHEMBL1923549 | US9676818, 6d)
Affinity DataEC50:  3.63nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50386536(CHEMBL2048220 | US9676818, 16)
Affinity DataEC50:  5.52nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50386537(CHEMBL2048077 | US9676818, 11f)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50386538(CHEMBL2048076 | US9676818, 11e)
Affinity DataEC50:  1.64nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50386539(CHEMBL2048067 | US9676818, 6e)
Affinity DataEC50:  4.79nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50358550(CHEMBL1923549 | US9676818, 6d)
Affinity DataEC50:  3.63E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50386539(CHEMBL2048067 | US9676818, 6e)
Affinity DataEC50:  4.79E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50386534(CHEMBL2048075 | US9676818, 11d)
Affinity DataEC50:  1.01E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50386538(CHEMBL2048076 | US9676818, 11e)
Affinity DataEC50:  1.64E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50386537(CHEMBL2048077 | US9676818, 11f)
Affinity DataEC50:  3.80E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50386535(CHEMBL2048219 | US9676818, 11h)
Affinity DataEC50:  4.45E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM199102(US9676818, chem-us-00156)
Affinity DataEC50:  2.97E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM199104(US9676818, 14b)
Affinity DataEC50:  5.47E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM199106(US9676818, 14c)
Affinity DataEC50:  5.95E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50386536(CHEMBL2048220 | US9676818, 16)
Affinity DataEC50:  5.52E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM199112(US9676818, 23)
Affinity DataEC50:  225nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM199114(US9676818, 25)
Affinity DataEC50:  6.81E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM199116(US9676818, 26)
Affinity DataEC50:  7.10E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

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