Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Thiopurine S-methyltransferase'
TargetThiopurine S-methyltransferase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to thiopurine methyltransferase (unknown origin) by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetThiopurine S-methyltransferase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50530712(CHEMBL4591248)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human TPMT expressed in Escherichia coli assessed as reduction in SAH level using 6-mercaptopurine as substrate in presence of SAM incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetThiopurine S-methyltransferase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50530712(CHEMBL4591248)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human TPMT expressed in Escherichia coli assessed as reduction in SAH level using 6-mercaptopurine as substrate in presence of SAM incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed