Compile Data Set for Download or QSAR
Report error Found 188 Enz. Inhib. hit(s) with Target = 'Taste receptor type 2 member 1'
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataEC50: <1.00E+4nMAssay Description:Agonist activity at human TAS2R14 expressed in U2OS cells by Ga16gust44 Clone 7A FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetTaste receptor type 2 member 16(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50044849(CHEMBL3311308)
Affinity DataEC50: <5.01E+4nMAssay Description:Agonist activity at human TAS2R16 expressed in U2OS cells by summary (Abse5) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetTaste receptor type 2 member 1(Human)
Firmenich

Curated by ChEMBL
LigandPNGBDBM211262(US9247759, 10-10)
Affinity DataEC50:  1.50E+5nMAssay Description:Agonist activity at TAS2R1 (unknown origin) by stably expressed cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM211262(US9247759, 10-10)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at TAS2R14 (unknown origin) by stably expressed cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataEC50:  430nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124575(CHEMBL3623735)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50385711(CHEMBL22815)
Affinity DataEC50:  950nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613012(CHEMBL5276181)
Affinity DataEC50:  930nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613013(CHEMBL5285283)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613014(CHEMBL5278171)
Affinity DataEC50:  330nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613015(CHEMBL5279381)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613016(CHEMBL5275001)
Affinity DataEC50:  390nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613017(CHEMBL5288875)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613018(CHEMBL5278834)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613019(CHEMBL3088246)
Affinity DataEC50:  230nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613020(CHEMBL5286379)
Affinity DataEC50:  640nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613021(CHEMBL5277615)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613022(CHEMBL5289590)
Affinity DataEC50:  420nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613023(CHEMBL5273955)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613024(CHEMBL5278477)
Affinity DataEC50:  380nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613025(CHEMBL5279341)
Affinity DataEC50:  670nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613026(CHEMBL5268477)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613027(CHEMBL5274977)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613028(CHEMBL5285591)
Affinity DataEC50:  98nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613029(CHEMBL5265867)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613030(CHEMBL5274470)
Affinity DataEC50:  360nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613031(CHEMBL5265924)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613032(CHEMBL5274304)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613033(CHEMBL5279691)
Affinity DataEC50:  72nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613034(CHEMBL5268924)
Affinity DataEC50:  640nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613035(CHEMBL5279932)
Affinity DataEC50:  6.80E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613036(CHEMBL5280688)
Affinity DataEC50:  540nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613037(CHEMBL5289980)
Affinity DataEC50:  750nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613038(CHEMBL5277281)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613039(CHEMBL5280454)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613040(CHEMBL5280542)
Affinity DataEC50:  180nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50613041(CHEMBL5275180)
Affinity DataEC50:  100nMAssay Description:Partial agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM211090(US9247759, 5-11)
Affinity DataIC50: 14nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM211181(US9247759, 5-128)
Affinity DataIC50: 36nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM211114(US9247759, 5-37)
Affinity DataIC50: 54nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM211099(US9247759, 5-20)
Affinity DataIC50: 83nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM211176(US9247759, 5-123)
Affinity DataIC50: 92nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM211179(US9247759, 5-126)
Affinity DataIC50: 109nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM211119(US9247759, 5-43)
Affinity DataIC50: 188nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM60947(US9247759, compound C | BDBM50443972)
Affinity DataIC50: 200nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM60947(US9247759, compound C | BDBM50443972)
Affinity DataIC50: 220nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM211101(US9247759, 5-22)
Affinity DataIC50: 240nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM55311(cid_1518966 | N-(1,3-benzodioxol-5-yl)-1,3-dimethy...)
Affinity DataIC50: 264nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM211237(US9247759, 6-24)
Affinity DataIC50: 292nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

TargetTaste receptor type 2 member 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM211169(US9247759, 5-115)
Affinity DataIC50: 334nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
Go to US Patent

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