Compile Data Set for Download or QSAR
Report error Found 553 Enz. Inhib. hit(s) with Target = 'Sphingomyelin phosphodiesterase'
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521402(CHEMBL4471834)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370179(CHEMBL4163007)
Affinity DataIC50: 20nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521404(CHEMBL4449307)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521405(CHEMBL4551018)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM67506(4-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-2,6...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521420(CHEMBL4467223)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521425(CHEMBL4449305)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520416(CHEMBL4553570)
Affinity DataIC50: 20nMAssay Description:Inhibition of acid sphingomyelinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521419(CHEMBL1342201)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521419(CHEMBL1342201)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521406(CHEMBL4458407)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521413(CHEMBL4565746)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540386(CHEMBL4647644 | US11427590, Entry 44 | US202401155...)
Affinity DataIC50: 50nMAssay Description:The fluorescence based assay to monitor the activity of human nSMase2 in the presence or absence of potential inhibitors has been described recently....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM570145(US11427590, Entry 62 | US20240115574, Entry 62)
Affinity DataIC50: 50nMAssay Description:The fluorescence based assay to monitor the activity of human nSMase2 in the presence or absence of potential inhibitors has been described recently....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540386(CHEMBL4647644 | US11427590, Entry 44 | US202401155...)
Affinity DataIC50: 50nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM570145(US11427590, Entry 62 | US20240115574, Entry 62)
Affinity DataIC50: 50nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521408(CHEMBL4468906)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370125(CHEMBL4176817)
Affinity DataIC50: 70nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521399(CHEMBL4588691)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521407(CHEMBL4577390)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521427(CHEMBL4533205)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521428(CHEMBL4471548)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540386(CHEMBL4647644 | US11427590, Entry 44 | US202401155...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521421(CHEMBL4514045)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540378(CHEMBL4634085 | US11427590, Entry 22 | US202401155...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540378(CHEMBL4634085 | US11427590, Entry 22 | US202401155...)
Affinity DataIC50: 90nMAssay Description:The fluorescence based assay to monitor the activity of human nSMase2 in the presence or absence of potential inhibitors has been described recently....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540378(CHEMBL4634085 | US11427590, Entry 22 | US202401155...)
Affinity DataIC50: 90nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540363(CHEMBL4643888 | US11427590, Entry 32 | US202401155...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540366(CHEMBL4635335 | US11427590, Entry 37 | US202401155...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540376(CHEMBL4644091 | US11427590, Entry 24 | US202401155...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540383(CHEMBL4635273 | US11427590, Entry 25 | US202401155...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM570104(US11427590, Entry 21 | US20240115574, Entry 21)
Affinity DataIC50: 100nMAssay Description:The fluorescence based assay to monitor the activity of human nSMase2 in the presence or absence of potential inhibitors has been described recently....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540376(CHEMBL4644091 | US11427590, Entry 24 | US202401155...)
Affinity DataIC50: 100nMAssay Description:The fluorescence based assay to monitor the activity of human nSMase2 in the presence or absence of potential inhibitors has been described recently....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540383(CHEMBL4635273 | US11427590, Entry 25 | US202401155...)
Affinity DataIC50: 100nMAssay Description:The fluorescence based assay to monitor the activity of human nSMase2 in the presence or absence of potential inhibitors has been described recently....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540363(CHEMBL4643888 | US11427590, Entry 32 | US202401155...)
Affinity DataIC50: 100nMAssay Description:The fluorescence based assay to monitor the activity of human nSMase2 in the presence or absence of potential inhibitors has been described recently....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540366(CHEMBL4635335 | US11427590, Entry 37 | US202401155...)
Affinity DataIC50: 100nMAssay Description:The fluorescence based assay to monitor the activity of human nSMase2 in the presence or absence of potential inhibitors has been described recently....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM570104(US11427590, Entry 21 | US20240115574, Entry 21)
Affinity DataIC50: 100nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540376(CHEMBL4644091 | US11427590, Entry 24 | US202401155...)
Affinity DataIC50: 100nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540383(CHEMBL4635273 | US11427590, Entry 25 | US202401155...)
Affinity DataIC50: 100nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540363(CHEMBL4643888 | US11427590, Entry 32 | US202401155...)
Affinity DataIC50: 100nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540366(CHEMBL4635335 | US11427590, Entry 37 | US202401155...)
Affinity DataIC50: 100nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521412(CHEMBL4540577)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521430(CHEMBL4573101)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521429(CHEMBL4436316)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540349(CHEMBL4648675 | US11427590, Entry 9 | US2024011557...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540356(CHEMBL4632464 | US11427590, Entry 17 | US202401155...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540365(CHEMBL4633254 | US11427590, Entry 34 | US202401155...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540369(CHEMBL4632713 | US11427590, Entry 19 | US202401155...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540372(CHEMBL4648184 | US11427590, Entry 42 | US202401155...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50540381(CHEMBL4632415 | US11427590, Entry 30 | US202401155...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
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