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Report error Found 105 Enz. Inhib. hit(s) with Target = 'Sodium/potassium-transporting ATPase subunit alpha-1'
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  553nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  6.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM46356(SMR000058529 | cid_441207 | MLS000069787 | DIGITOX...)
Affinity DataIC50: 8nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408112(CHEMBL2069115)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408116(CHEMBL2069118)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408117(CHEMBL2069066)
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408111(CHEMBL2069075)
Affinity DataIC50: 45.5nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50161249(3a,11a-dihydroxy-4''-imino-9,15a-dimethyl-1-(5-oxo...)
Affinity DataIC50: 68nMAssay Description:In vitro inhibitory activity against porcine Na+/K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50161262(11a-hydroxy-3a,13a-di(hydroxymethyl)-9,15a-dimethy...)
Affinity DataIC50: 75nMAssay Description:In vitro inhibitory activity against porcine Na+/K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50605867(CHEMBL469045 | US12343350, Compound ISTAROXIME)
Affinity DataIC50: 140nMAssay Description:Inhibition of Beagle dog kidney NA+/K+ ATPase alpha 1 by measuring 32P-ATP hydrolysis preincubated for 10 mins followed by addition of 32P-ATP measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50605867(CHEMBL469045 | US12343350, Compound ISTAROXIME)
Affinity DataIC50: 140nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408276(CHEMBL2068996)
Affinity DataIC50: 160nMAssay Description:Inhibition of Na+/K+ ATPase from dog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM46355(MLS000069819 | cid_2724385 | SMR000059217 | DIGOXI...)
Affinity DataIC50: 180nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408114(CHEMBL2069070)
Affinity DataIC50: 230nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408439(CHEMBL2068890)
Affinity DataIC50: 250nMAssay Description:In vitro inhibitory concentration against dog kidney Na+,K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM46355(MLS000069819 | cid_2724385 | SMR000059217 | DIGOXI...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human kidney Na(+)/K(+) ATPase alpha-1 assessed as amount of Pi release after 1 hr by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408921(CHEMBL2068972)
Affinity DataIC50: 320nMAssay Description:In vitro inhibitory concentration against dog kidney Na+,K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50096255(CHEMBL3594278)
Affinity DataIC50: 340nMAssay Description:Inhibition of human kidney Na(+)/K(+) ATPase alpha-1 assessed as amount of Pi release after 1 hr by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM66977(Digitoxigenin | cid_4369270 | MLS002153810 | 3-[(3...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Na+/K+ ATPase from dog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM46355(MLS000069819 | cid_2724385 | SMR000059217 | DIGOXI...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Na+/K+ ATPase from dog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM46355(MLS000069819 | cid_2724385 | SMR000059217 | DIGOXI...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory concentration against dog kidney Na+,K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM66977(Digitoxigenin | cid_4369270 | MLS002153810 | 3-[(3...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory concentration against dog kidney Na+,K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50096254(CHEMBL3594276)
Affinity DataIC50: 570nMAssay Description:Inhibition of human kidney Na(+)/K(+) ATPase alpha-1 assessed as amount of Pi release after 1 hr by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408115(CHEMBL2069067)
Affinity DataIC50: 660nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408917(CHEMBL2068902)
Affinity DataIC50: 1.25E+3nMAssay Description:In vitro inhibitory concentration against dog kidney Na+,K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408275(CHEMBL2068885)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of Na+/K+ ATPase from dog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408916(CHEMBL2068975)
Affinity DataIC50: 1.58E+3nMAssay Description:In vitro inhibitory concentration against dog kidney Na+,K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50161244(Uscharin derivative | CHEMBL369515)
Affinity DataIC50: 1.89E+3nMAssay Description:In vitro inhibitory activity against porcine Na+/K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408119(CHEMBL2069069)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408282(CHEMBL2069057)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Na+/K+ ATPase from dog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM754081(US12343350, Compound 2915)
Affinity DataIC50: 2.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408113(CHEMBL2069072)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408281(CHEMBL2068940 | CHEMBL2068935)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Na+/K+ ATPase from dog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408118(CHEMBL2069074)
Affinity DataIC50: 3.22E+3nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408279(CHEMBL2069128)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of Na+/K+ ATPase from dog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50161268(Uscharin derivative | CHEMBL366906)
Affinity DataIC50: 4.08E+3nMAssay Description:In vitro inhibitory activity against porcine Na+/K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50286739(4-[1,5,11,14-Tetrahydroxy-10-hydroxymethyl-13-meth...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant rat Na+/K+-ATPase alpha1/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408120(CHEMBL2069071)
Affinity DataIC50: 4.73E+3nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408280(CHEMBL2068992)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Na+/K+ ATPase from dog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408920(CHEMBL2069058)
Affinity DataIC50: 6.30E+3nMAssay Description:In vitro inhibitory concentration against dog kidney Na+,K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408278(CHEMBL2068942)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of Na+/K+ ATPase from dog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408281(CHEMBL2068940 | CHEMBL2068935)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of Na+/K+ ATPase from dog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408277(CHEMBL2068936)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of Na+/K+ ATPase from dog kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Rat)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50409816(ABAMECTIN)
Affinity DataIC50: 8.23E+3nMAssay Description:Inhibition of Wistar rat kidney Na+,K+-ATPase alpha1 after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50096256(CHEMBL3594279)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human kidney Na(+)/K(+) ATPase alpha-1 assessed as amount of Pi release after 1 hr by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50096257(CHEMBL3594280)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human kidney Na(+)/K(+) ATPase alpha-1 assessed as amount of Pi release after 1 hr by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
LigandPNGBDBM50161245(11a-hydroxy-3a-hydroxymethyl-4''-imino-9,15a-dimet...)
Affinity DataIC50: 1.21E+4nMAssay Description:In vitro inhibitory activity against porcine Na+/K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408915(CHEMBL2068981)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibitory concentration against dog kidney Na+,K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50408914(CHEMBL2068977)
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro inhibitory concentration against dog kidney Na+,K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50161253(Uscharin derivative | CHEMBL426228)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibitory activity against porcine Na+/K+-ATPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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