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Report error Found 85 Enz. Inhib. hit(s) with Target = 'Sodium/nucleoside cotransporter'
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172392(CHEMBL3808747)
Affinity DataIC50: 62nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085527(CHEMBL3427690)
Affinity DataIC50: 640nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085527(CHEMBL3427690)
Affinity DataIC50: 640nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172396(CHEMBL3809613)
Affinity DataIC50: 940nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172411(CHEMBL3809974)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172403(CHEMBL3809075)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172397(CHEMBL3809514)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172409(CHEMBL3808410)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172408(CHEMBL3809978)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172404(CHEMBL3809204)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172412(CHEMBL3809948)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Rat)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172392(CHEMBL3808747)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172394(CHEMBL3809286)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172407(CHEMBL3810002)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172410(CHEMBL3808652)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172398(CHEMBL3808498)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172400(CHEMBL3808970)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172406(CHEMBL3808769)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085530(CHEMBL3427687)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085538(CHEMBL3427681)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172402(CHEMBL3808969)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 1(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 5.50E+3nMAssay Description:Binding affinity to recombinant human CNT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172399(CHEMBL3808734)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 5.50E+3nMAssay Description:Binding affinity to recombinant human CNT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085532(CHEMBL3427686)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085539(CHEMBL3427680)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 1(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50088517(CHEBI:16704 | Uridine)
Affinity DataIC50: 5.80E+3nMAssay Description:Binding affinity to recombinant human CNT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172401(CHEMBL3808405)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50608215(CHEMBL5270911)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CNT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CNT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSodium/nucleoside cotransporter 1(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CNT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172405(CHEMBL3809428)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085540(CHEMBL3427679)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085537(CHEMBL3427682)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085534(CHEMBL3427684)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085542(CHEMBL3427678)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172393(CHEMBL3809118)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of human CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085528(CHEMBL3427689)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50088517(CHEBI:16704 | Uridine)
Affinity DataIC50: 3.20E+4nMAssay Description:Binding affinity to recombinant human CNT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085533(CHEMBL3427685)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Rat)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172396(CHEMBL3809613)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of rat CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 1(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50138530((2R,3S,4R)-2-Hydroxymethyl-5-{6-[(R)-(tetrahydro-f...)
Affinity DataIC50: 4.10E+4nMAssay Description:Binding affinity to recombinant human CNT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Rat)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172397(CHEMBL3809514)
Affinity DataIC50: 4.51E+4nMAssay Description:Inhibition of rat CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 1(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50608215(CHEMBL5270911)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of human CNT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM32372(adenosine-derived inhibitor, 6)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 1(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50608214(CHEMBL5285935)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of human CNT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSodium/nucleoside cotransporter 2(Rat)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50172394(CHEMBL3809286)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of rat CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085543(CHEMBL3427677)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085464(CHEMBL3427697)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50085525(CHEMBL3427691)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
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