Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 5'
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50196789(CHEMBL3892788)
Affinity DataIC50: 291nMAssay Description:Inhibition of human NHE5 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 1.51E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639614(CHEMBL5565656)
Affinity DataIC50: 3.11E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50104844(N-[(1R,3R)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...)
Affinity DataIC50: 3.36E+3nMAssay Description:Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639611(CHEMBL5568323)
Affinity DataIC50: 4.54E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639608(CHEMBL5542750)
Affinity DataIC50: 4.75E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639606(CHEMBL5560204)
Affinity DataIC50: 5.58E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639609(CHEMBL5567224)
Affinity DataIC50: 8.83E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639607(CHEMBL5556133)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639621(CHEMBL5556438)
Affinity DataIC50: 1.11E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639604(CHEMBL5563696)
Affinity DataIC50: 1.59E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639618(CHEMBL5563134)
Affinity DataIC50: 1.62E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639619(CHEMBL5561147)
Affinity DataIC50: 1.83E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639610(CHEMBL5555889)
Affinity DataIC50: 2.20E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | N-(diaminomethylene)-2-m...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639605(CHEMBL5559174)
Affinity DataIC50: 3.01E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639616(CHEMBL5560463)
Affinity DataIC50: 3.01E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639615(CHEMBL5562697)
Affinity DataIC50: 4.34E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM32332(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)
Affinity DataIC50: 4.95E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639600(CHEMBL5561432)
Affinity DataIC50: 5.51E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639620(CHEMBL5555508)
Affinity DataIC50: 6.95E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639612(CHEMBL5566999)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639613(CHEMBL5558607)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639617(CHEMBL5562282)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639601(CHEMBL5560348)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639602(CHEMBL5566603)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50639603(CHEMBL5559101)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed