Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein phosphatase 5'
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217370(IEEVD)
Affinity DataKd:  426nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50646842(CHEMBL5593159)
Affinity DataKd:  0.540nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50646842(CHEMBL5593159)
Affinity DataKd:  3.72E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50646843(CHEMBL5592027)
Affinity DataKd:  1.44E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50646843(CHEMBL5592027)
Affinity DataKd:  1.66E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50646842(CHEMBL5593159)
Affinity DataKd:  811nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50646842(CHEMBL5593159)
Affinity DataKd:  1.14E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50646842(CHEMBL5593159)
Affinity DataEC50:  5.28E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50408824(CHAULMOOGRIC ACID | CHEBI:61391 | Chaulmoogric Aci...)
Affinity DataEC50:  1.30nMAssay Description:Activation of recombinant human PP5 (16 to 499 residues) Escherichia coli BL21 (DE3) using pNPP incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM22319([1-14C]Arachidonic acid | (5Z,8Z,11Z,14Z)-icosa-5,...)
Affinity DataEC50:  7.80nMAssay Description:Activation of recombinant human PP5 (16 to 499 residues) Escherichia coli BL21 (DE3) using pNPP incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50618394(CHEMBL5402473)
Affinity DataEC50:  1.35E+5nMAssay Description:Activation of PPP5C (unknown origin) TPR domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM22319([1-14C]Arachidonic acid | (5Z,8Z,11Z,14Z)-icosa-5,...)
Affinity DataEC50:  7.76E+4nMAssay Description:Activation of PPP5C (unknown origin) TPR domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50367033(COENZYME_A)
Affinity DataEC50:  1nMAssay Description:Activation of PPP5C (unknown origin) TPR domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50618393(CHEMBL1343129)
Affinity DataKd:  7.80E+3nMAssay Description:Binding affinity to rat PPP5C (428 to 430 residues) phosphatase domain expressed in Escherichia coli BL21-codonplus (DE3)-RIL cells using para-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217369(MEEVD)
Affinity DataKd:  140nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217373(SSGPTIEEVD)
Affinity DataKd:  1.06E+3nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217374(GSGPTIEEVD)
Affinity DataKd:  1.55E+3nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217371(DDTSRMEEVD)
Affinity DataKd:  79nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217372(EDASRMEEVD)
Affinity DataKd:  77nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217375(DVEEM)
Affinity DataKd: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217377(GSGPTMEEVD)
Affinity DataKd:  133nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM217376(DDTSRIEEVD)
Affinity DataKd:  420nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50061067(8-[3-amino(imino)methylaminopropyl]-15-isobutyl-5-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PP5 (unknown origin) using [3H]-phosphohistone as substrate by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50061067(8-[3-amino(imino)methylaminopropyl]-15-isobutyl-5-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50110681(Calyculin-A | CHEMBL430266)
Affinity DataIC50: 3nMAssay Description:Inhibition of human PP5 using [3H]-phosphohistone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50647778(CHEMBL5597987)
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50408820(CHEMBL5268133)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50408822(CHEMBL5276260)
Affinity DataIC50: 4nMAssay Description:Inhibition of PP5 (unknown origin) using [3H]-phosphohistone as substrate by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50366883(TAUTOMYCIN)
Affinity DataIC50: 10nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50408823(CHEMBL5276593)
Affinity DataIC50: 12nMAssay Description:Inhibition of PP5 (unknown origin) using [3H]-phosphohistone as substrate by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50639669(CHEMBL5561795)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50090505((1R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human PP5 using [3H]-phosphohistone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50090505((1R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2...)
Affinity DataIC50: 600nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50090505((1R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2...)
Affinity DataIC50: 600nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domain using phosphohistone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50618392(CHEMBL5405890)
Affinity DataIC50: 700nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50618391(CHEMBL5421006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50090503((1R,2S,6R,7S)-4,10-Dioxa-tricyclo[5.2.1.0*2,6*]dec...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50618390(CHEMBL5415208)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of MBP fused recombinant human PPP5C phosphatase domain expressed in Escherichia coli using DiFMUP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50639657(CHEMBL5558181)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50639658(CHEMBL5558644)
Affinity DataIC50: 2.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50646844(Lb-100 | LB 100)
Affinity DataIC50: 2.11E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50646844(Lb-100 | LB 100)
Affinity DataIC50: 2.21E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50112358(CHEMBL3609374)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PP5 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50112357(CHEMBL3609375)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PP5 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.00E+4nMpH: 7.0Assay Description:Inhibition of PP5 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PP5 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
University of Michigan

LigandPNGBDBM50607110(CHEMBL5219519)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
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