Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with Target = 'Ryanodine receptor 1 [4317-4329]'
TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430056(US10538528, Compound 43)
Affinity DataIC50: 0.400nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430057(US10538528, Compound 44)
Affinity DataIC50: 0.5nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430051(US10538528, Compound 37)
Affinity DataIC50: 0.5nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430053(US10538528, Compound 40)
Affinity DataIC50: 0.600nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430052(US10538528, Compound 39)
Affinity DataIC50: 0.600nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430047(US10538528, Compound 32)
Affinity DataIC50: 0.600nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430029(US10538528, Compound 5)
Affinity DataIC50: 0.700nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430030(US10538528, Compound 11)
Affinity DataIC50: 0.700nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430034(US10538528, Compound 16)
Affinity DataIC50: 0.800nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430038(US10538528, Compound 20)
Affinity DataIC50: 0.900nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430066(US10538528, Compound 38)
Affinity DataIC50: 0.900nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430050(US10538528, Compound 34)
Affinity DataIC50: 0.900nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430037(US10538528, Compound 19)
Affinity DataIC50: 0.900nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430063(US10538528, Compound 10)
Affinity DataIC50: 0.900nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430059(US10538528, Compound 6)
Affinity DataIC50: 1nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430049(US10538528, Compound 33)
Affinity DataIC50: 1nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430035(US10538528, Compound 17)
Affinity DataIC50: 1.10nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430062(US10538528, Compound 9)
Affinity DataIC50: 1.10nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430033(US10538528, Compound 15)
Affinity DataIC50: 1.10nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430055(US10538528, Compound 42)
Affinity DataIC50: 1.20nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430039(US10538528, Compound 21)
Affinity DataIC50: 1.30nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430036(US10538528, Compound 18)
Affinity DataIC50: 1.40nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430031(US10538528, Compound 13)
Affinity DataIC50: 1.40nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430065(US10538528, Compound 35)
Affinity DataIC50: 1.5nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430058(US10538528, Compound 2)
Affinity DataIC50: 1.5nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430028(US10538528, Compound 1)
Affinity DataIC50: 1.5nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430041(US10538528, Compound 23)
Affinity DataIC50: 1.5nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430054(US10538528, Compound 41)
Affinity DataIC50: 1.60nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430032(US10538528, Compound 14)
Affinity DataIC50: 1.70nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430061(US10538528, Compound 8)
Affinity DataIC50: 1.70nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430060(US10538528, Compound 7)
Affinity DataIC50: 1.70nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430045(US10538528, Compound 30)
Affinity DataIC50: 1.70nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430064(US10538528, Compound 12)
Affinity DataIC50: 1.80nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430046(US10538528, Compound 31)
Affinity DataIC50: 1.80nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430044(US10538528, Compound 27)
Affinity DataIC50: 1.80nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
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