Compile Data Set for Download or QSAR
Report error Found 151 Enz. Inhib. hit(s) with Target = 'Ryanodine receptor'
TargetRyanodine receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50241983(Bastadin-4 | CHEMBL453147 | Bastadin 4)
Affinity DataEC50:  1.47E+4nMAssay Description:Displacement of [3H]ryanodine from RyR1 calcium channel in sarcoplasmic reticulum assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRyanodine receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50241984(CHEMBL505907 | BASTADIN 6 | bastadin-6)
Affinity DataEC50:  2.60E+3nMAssay Description:Displacement of [3H]ryanodine from RyR1 calcium channel in sarcoplasmic reticulum assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRyanodine receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50241986(Bastadin-10 | CHEMBL504851)
Affinity DataEC50:  5.80E+3nMAssay Description:Displacement of [3H]ryanodine from RyR1 calcium channel in sarcoplasmic reticulum assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRyanodine receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50241985(CHEMBL508830 | Bastadin-19 | CHEMBL506286 | (E,Z)b...)
Affinity DataEC50: >1.00E+5nMAssay Description:Displacement of [3H]ryanodine from RyR1 calcium channel in sarcoplasmic reticulum assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRyanodine receptor(Fruit fly)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataEC50:  40nMAssay Description:Activation of Drosophila melanogaster ryanodine receptor in Sf9 cells assessed as induction of calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRyanodine receptor 1(Mouse)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataEC50:  1.40E+4nMAssay Description:Activation of ryanodine receptor 1 in mouse C2C12 cells assessed as induction of calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetRyanodine receptor(Fruit fly)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataEC50:  0.0500nMAssay Description:Activation of Drosophila melanogaster ryanodine receptor assessed as induction of calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetRyanodine receptor 2(Rat)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of ryanodine receptor 2 in rat PC12 cells assessed as induction of calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetRyanodine receptor 1(Rabbit)
University of California

Curated by ChEMBL
LigandPNGBDBM50191286(Bastadin-5 | bastadin 5 | CHEMBL439151)
Affinity DataEC50:  2.00E+3nMAssay Description:Displacement of [3H]ryanodine from Ry1R/FKBP12 receptor complex in rabbit sarcoplasmic reticulumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetRyanodine receptor 1(Rabbit)
University of California

Curated by ChEMBL
LigandPNGBDBM50292366(10-sulfatobastadin 3 | CHEMBL450681)
Affinity DataEC50:  1.00E+5nMAssay Description:Displacement of [3H]ryanodine from Ry1R/FKBP12 receptor complex in rabbit sarcoplasmic reticulumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetRyanodine receptor 1(Rabbit)
University of California

Curated by ChEMBL
LigandPNGBDBM50292367(15,34-O-disulfatobastadin 7 | CHEMBL509326)
Affinity DataEC50:  1.36E+4nMAssay Description:Displacement of [3H]ryanodine from Ry1R/FKBP12 receptor complex in rabbit sarcoplasmic reticulumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetRyanodine receptor 1(Rabbit)
University of California

Curated by ChEMBL
LigandPNGBDBM50292368(bastadin 20 | CHEMBL498932)
Affinity DataEC50:  2.06E+4nMAssay Description:Displacement of [3H]ryanodine from Ry1R/FKBP12 receptor complex in rabbit sarcoplasmic reticulumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetRyanodine receptor 1(Rabbit)
University of California

Curated by ChEMBL
LigandPNGBDBM50241985(CHEMBL508830 | Bastadin-19 | CHEMBL506286 | (E,Z)b...)
Affinity DataEC50: >1.00E+5nMAssay Description:Displacement of [3H]ryanodine from Ry1R/FKBP12 receptor complex in rabbit sarcoplasmic reticulumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetRyanodine receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50191278((+/-)-5,17-dibromo-4-hydroxy-2-oxa-10-aza-tricyclo...)
Affinity DataEC50:  1.10E+4nMAssay Description:Binding affinity to RYR1 channels by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetRyanodine receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50191286(Bastadin-5 | bastadin 5 | CHEMBL439151)
Affinity DataEC50:  2.20E+3nMAssay Description:Binding affinity to RYR1 channels by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetRyanodine receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50150778(polybrominated diphenyl ether derivative | Bastadi...)
Affinity DataEC50:  6.30E+3nMAssay Description:Binding affinity to RYR1 channels by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetRyanodine receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50241985(CHEMBL508830 | Bastadin-19 | CHEMBL506286 | (E,Z)b...)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to RYR1 channels by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetRyanodine receptor(Sea urchin)
Juntendo University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50238525(CHEMBL4106291)
Affinity DataEC50:  39nMAssay Description:Agonist activity at ryanodine receptor in Hemicentrotus pulcherrimus egg homogenate assessed as increase in intracellular calcium mobilization by Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2019
Entry Details Article
PubMed
TargetRyanodine receptor(Sea urchin)
Juntendo University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50238526(CHEMBL4106293)
Affinity DataEC50:  870nMAssay Description:Agonist activity at ryanodine receptor in Hemicentrotus pulcherrimus egg homogenate assessed as increase in intracellular calcium mobilization by Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2019
Entry Details Article
PubMed
TargetRyanodine receptor(Sea urchin)
Juntendo University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50238527(CHEMBL4106292)
Affinity DataEC50:  3.70E+4nMAssay Description:Agonist activity at ryanodine receptor in Hemicentrotus pulcherrimus egg homogenate assessed as increase in intracellular calcium mobilization by Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2019
Entry Details Article
PubMed
TargetRyanodine receptor(Sea urchin)
Juntendo University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50238528(CHEMBL4106294)
Affinity DataEC50:  1.20E+4nMAssay Description:Agonist activity at ryanodine receptor in Hemicentrotus pulcherrimus egg homogenate assessed as increase in intracellular calcium mobilization by Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2019
Entry Details Article
PubMed
TargetRyanodine receptor(Sea urchin)
Juntendo University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50238529(CHEMBL3350989)
Affinity DataEC50:  210nMAssay Description:Agonist activity at ryanodine receptor in Hemicentrotus pulcherrimus egg homogenate assessed as increase in intracellular calcium mobilization by Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2019
Entry Details Article
PubMed
TargetRyanodine receptor 2(Homo sapiens)
Max Planck Institute for Multidisciplinary Sciences

Curated by ChEMBL
LigandPNGBDBM50631111(CHEMBL5437537)
Affinity DataEC50:  8.17E+3nMAssay Description:Modulator activity at wild type RyR2 (unknown origin) expressed in HEK293T co-expressed with R-CEPIA1er assessed as decrease in RyR2-mediated calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRyanodine receptor 2(Homo sapiens)
Max Planck Institute for Multidisciplinary Sciences

Curated by ChEMBL
LigandPNGBDBM50631112(CHEMBL5398491)
Affinity DataEC50:  82nMAssay Description:Modulator activity at wild type RyR2 (unknown origin) expressed in HEK293T co-expressed with R-CEPIA1er assessed as decrease in RyR2-mediated calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRyanodine receptor 2(Homo sapiens)
Max Planck Institute for Multidisciplinary Sciences

Curated by ChEMBL
LigandPNGBDBM50631113(CHEMBL5413930)
Affinity DataEC50:  10nMAssay Description:Modulator activity at wild type RyR2 (unknown origin) expressed in HEK293T co-expressed with R-CEPIA1er assessed as decrease in RyR2-mediated calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRyanodine receptor 2(Homo sapiens)
Max Planck Institute for Multidisciplinary Sciences

Curated by ChEMBL
LigandPNGBDBM50631114(CHEMBL5435124)
Affinity DataEC50:  2.70E+3nMAssay Description:Modulator activity at wild type RyR2 (unknown origin) expressed in HEK293T co-expressed with R-CEPIA1er assessed as decrease in RyR2-mediated calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRyanodine receptor 2(Homo sapiens)
Max Planck Institute for Multidisciplinary Sciences

Curated by ChEMBL
LigandPNGBDBM50631115(CHEMBL5426069)
Affinity DataEC50: >2.30E+4nMAssay Description:Modulator activity at wild type RyR2 (unknown origin) expressed in HEK293T co-expressed with R-CEPIA1er assessed as decrease in RyR2-mediated calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRyanodine receptor 2(Homo sapiens)
Max Planck Institute for Multidisciplinary Sciences

Curated by ChEMBL
LigandPNGBDBM50631116(CHEMBL5409619)
Affinity DataEC50:  19nMAssay Description:Modulator activity at wild type RyR2 (unknown origin) expressed in HEK293T co-expressed with R-CEPIA1er assessed as decrease in RyR2-mediated calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652435(CHEMBL5639308)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652436(CHEMBL5641625)
Affinity DataEC50:  696nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652437(CHEMBL5639574)
Affinity DataEC50:  4.08E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652438(CHEMBL5647410)
Affinity DataEC50:  2.94E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652439(CHEMBL5647160)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652440(CHEMBL5646642)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652441(CHEMBL5646903)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652442(CHEMBL5647325)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652443(CHEMBL5639709)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652444(CHEMBL5639384)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652445(CHEMBL5646503)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652446(CHEMBL5639268)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652447(CHEMBL5641646)
Affinity DataEC50:  2.92E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652448(CHEMBL5646849)
Affinity DataEC50:  180nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652449(CHEMBL5639305)
Affinity DataEC50:  1.23E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652450(CHEMBL5641758)
Affinity DataEC50:  460nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652451(CHEMBL5639861)
Affinity DataEC50:  96nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652452(CHEMBL5647159)
Affinity DataEC50:  220nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652453(CHEMBL5646836)
Affinity DataEC50:  22nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652454(CHEMBL5639438)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652455(CHEMBL5641717)
Affinity DataEC50:  2.50E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRyanodine receptor 2(Mouse)
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50652456(CHEMBL5647032)
Affinity DataEC50:  136nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
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