Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Ribonucleoside-diphosphate reductase large subunit/subunit M2 B'
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2 B(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50214817(N6-aminoadenosine | CHEMBL236757)
Affinity DataIC50: 2.44E+5nMAssay Description:Inhibition of human recombinant ribonucleotide reductase p53R2/M1 expressed in Escherichia coli BL21 (DE3) after 30 mins by [3H]CDP reduction methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2 B(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50497567(CHEMBL3337770)
Affinity DataKi:  4.00E+5nMAssay Description:Competitive inhibition of human recombinant ribonucleotide reductase in presence of varying levels of ATP by Dixon plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed