Compile Data Set for Download or QSAR
Report error Found 4198 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH'
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50620682(CHEMBL513181 | Ro-9187)
Affinity DataEC50:  0.0300nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50620683(CHEMBL5398494)
Affinity DataEC50:  0.0300nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 0.0910nMAssay Description:Inhibition of HIV-1BH10 reverse transcriptase expressed in Escherichia coli assessed as polymerization by real time FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 0.0910nMAssay Description:Inhibition of wild type HIV-1 NL4-3 reverse transcriptase using random mRNA as template and GADPH as primer measured at 42 degreeC for 5 mins, 95 deg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50610496(CHEMBL441158)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of HIV-1 reverse transcriptase incubated for 90 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50597919(CHEMBL5187795)
Affinity DataEC50:  0.200nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptase assessed as reduction in luciferase reporter activity by single-round assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50594991(CHEMBL415320)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of HIV-1 reverse transcriptase using rC.dG as primer/templateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50094288(5-(2,6-Diamino-purin-9-yl)-2-ethynyl-2-hydroxymeth...)
Affinity DataEC50:  0.300nMAssay Description:Tested in vitro against HIV-1 LAI from MT-4 cells using MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50594992(CHEMBL316785)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of HIV-1 reverse transcriptase using rC.dG as primer/templateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM222178(Rilpivirine)
Affinity DataEC50:  0.400nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptase assessed as reduction in luciferase reporter activity by single-round assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50572547(CHEMBL4868702)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of wild type HIV-1 NL4-3 reverse transcriptase using random mRNA as template and GADPH as primer measured at 42 degreeC for 5 mins, 95 deg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50032238(6-(3',5'-DIMETHYLBENZYL)-1-ETHOXYMETHYL-5-ISOPROPY...)
Affinity DataEC50:  0.600nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 0.75nMAssay Description:Inhibitory concentration against wild-type reverse transcriptase of HIV-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50591802(CHEMBL5187675)
Affinity DataIC50: 1nMAssay Description:Inhibition of HIV-1 reverse transcriptase preincubated for 45 mins followed by substrate addition by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataEC50:  1nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50094288(5-(2,6-Diamino-purin-9-yl)-2-ethynyl-2-hydroxymeth...)
Affinity DataEC50:  1.30nMAssay Description:Tested in vitro against HIV-1 MDR using MAGI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50171981(4-[2-(5-Ethyl-7,10-dimethyl-11-oxo-10,11-dihydro-5...)
Affinity DataEC50:  1.30nMAssay Description:Effective concentration towards HIV-1 wild type reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50094282(2-Amino-9-(5-ethynyl-4-hydroxy-5-hydroxymethyl-tet...)
Affinity DataEC50:  1.40nMAssay Description:Tested in vitro against HIV-1 LAI from MT-4 cells using MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50070536(1-(5-Chloro-pyridin-2-yl)-3-[(1R,2R)-2-(3-ethoxy-2...)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory effect on wild type HIV- 1 reverse transcriptase using rCdG as template and dGTP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50094286(4-Amino-1-(5-ethynyl-4-hydroxy-5-hydroxymethyl-tet...)
Affinity DataEC50:  1.5nMAssay Description:Tested in vitro against HIV-1 MDR using MAGI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50572539(CHEMBL4872125)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of wild type HIV-1 NL4-3 reverse transcriptase using random mRNA as template and GADPH as primer measured at 42 degreeC for 5 mins, 95 deg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50171976(4-[2-(5-Ethyl-7-fluoro-10-methyl-11-oxo-10,11-dihy...)
Affinity DataEC50:  1.5nMAssay Description:Effective concentration towards HIV-1 wild type reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50070535(1-[(1R,2R)-2-(6-Chloro-3-ethoxy-2-fluoro-phenyl)-c...)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory effect on wild type HIV- 1 reverse transcriptase using rCdG as template and dGTP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50171971(4-[2-(5-Ethyl-10-methyl-11-oxo-10,11-dihydro-5H-4,...)
Affinity DataEC50:  1.60nMAssay Description:Effective concentration towards HIV-1 wild type reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50171982(4-[2-(7-Chloro-5-ethyl-10-methyl-11-oxo-10,11-dihy...)
Affinity DataEC50:  1.60nMAssay Description:Effective concentration towards HIV-1 wild type reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50032235(6-(3,5-dimethylbenzyl)-1-ethoxymethyl-5-ethyl-1,2,...)
Affinity DataEC50:  1.60nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50171974(4-[2-(5-Ethyl-7-methoxy-10-methyl-11-oxo-10,11-dih...)
Affinity DataEC50:  1.90nMAssay Description:Effective concentration towards HIV-1 wild type reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM2337(CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...)
Affinity DataEC50:  2nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50070531(1-(5-Chloro-pyridin-2-yl)-3-[(1R,2R)-2-(2-fluoro-3...)
Affinity DataIC50: 2nMAssay Description:Inhibitory effect on wild type HIV- 1 reverse transcriptase using rCdG as template and dGTP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50556161(CHEMBL4759261)
Affinity DataIC50: 2nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of recombinant HIV-1 p66/p51 reverse transcriptase K103N mutant assessed as inhibition of [3H]dTT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50070533(1-(5-Chloro-pyridin-2-yl)-3-[(1R,2R)-2-(2,6-difluo...)
Affinity DataIC50: 2nMAssay Description:Inhibitory effect on wild type HIV- 1 reverse transcriptase using rCdG as template and dGTP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataEC50:  2nMAssay Description:Effective concentration required to achieve 50% inhibition of HIV-1 LAI replication in human T4 lymphoblastoid CEM-SS cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50171980(3-Ethyl-4-[2-(5-ethyl-10-methyl-11-oxo-10,11-dihyd...)
Affinity DataEC50:  2.20nMAssay Description:Effective concentration towards HIV-1 wild type reverse transcriptase activity by 50% measured in cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50572548(CHEMBL4865743)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of wild type HIV-1 NL4-3 reverse transcriptase using random mRNA as template and GADPH as primer measured at 42 degreeC for 5 mins, 95 deg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50008329(CHEMBL276108 | 6-(3,5-Dimethyl-phenylsulfanyl)-1-(...)
Affinity DataEC50:  2.70nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50008329(CHEMBL276108 | 6-(3,5-Dimethyl-phenylsulfanyl)-1-(...)
Affinity DataEC50:  2.70nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50032236(6-(3,5-Dimethyl-benzyl)-1-(2-hydroxy-ethoxymethyl)...)
Affinity DataEC50:  2.70nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50004148(CHEMBL39015 | 1-Benzyloxymethyl-5-isopropyl-6-phen...)
Affinity DataEC50:  2.70nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50004148(CHEMBL39015 | 1-Benzyloxymethyl-5-isopropyl-6-phen...)
Affinity DataEC50:  2.70nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50572562(CHEMBL4868890)
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type HIV-1 NL4-3 reverse transcriptase using random mRNA as template and GADPH as primer measured at 42 degreeC for 5 mins, 95 deg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50183190(2-(1-(2-bromo-4-methylphenyl)-1H-tetrazol-5-ylthio...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HIV1 wild type Reverse TranscriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by triplicate assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataEC50:  3nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50183200(3-chloro-4-(2-(1-mesityl-1H-tetrazol-5-ylthio)acet...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HIV1 wild type Reverse TranscriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM1803(2-amino-6-[(3-bromo-5-methylbenzene)sulfonyl]benzo...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against Reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataEC50:  3nMAssay Description:Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataEC50:  3nMAssay Description:Effective concentration in vitro against HIV-1-infected CEM cells relative to uninfected untreated controlsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards wild type HIV-1 reverse transcriptase (as per ref 10 in the article)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50550025(CHEMBL1923490)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant wild type HIV-1 reverse transcriptase using poly(rA)350/oligo(dT)16 as template/primer preincubated for 1 hr followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
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