Compile Data Set for Download or QSAR
Report error Found 104 Enz. Inhib. hit(s) with Target = 'RNA-binding protein FXR1'
TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504301(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  230nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504302(3α,7α,11β,23-tetrahydroxy-6α-e...)
Affinity DataEC50:  7.5nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504300(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  680nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504303(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  264nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  15nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504305(US11034717, Compound A)
Affinity DataEC50:  200nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504306(US11034717, Compound B)
Affinity DataEC50:  30nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504307(US11034717, Compound C)
Affinity DataEC50:  1.75E+5nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504309(US11034717, Compound L1)
Affinity DataEC50:  150nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504302(3α,7α,11β,23-tetrahydroxy-6α-e...)
Affinity DataEC50:  7.5nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  15nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504310(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  42nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504311(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  29nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504309(US11034717, Compound L1)
Affinity DataEC50:  150nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Mouse)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504309(US11034717, Compound L1)
Affinity DataEC50:  990nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Rat)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504309(US11034717, Compound L1)
Affinity DataEC50:  1.00E+3nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504302(3α,7α,11β,23-tetrahydroxy-6α-e...)
Affinity DataEC50:  7.5nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Mouse)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504302(3α,7α,11β,23-tetrahydroxy-6α-e...)
Affinity DataEC50:  250nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Rat)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504302(3α,7α,11β,23-tetrahydroxy-6α-e...)
Affinity DataEC50:  130nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  15nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Mouse)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  120nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Rat)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504304(3α,7α,11β-rihydroxy-6α-ethyl-5...)
Affinity DataEC50:  140nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504310(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  42nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Mouse)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504310(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  270nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Rat)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504310(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  240nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Human)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504311(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  29nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Mouse)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504311(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  210nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1(Rat)
Intercept Pharmaceuticals

US Patent
LigandPNGBDBM504311(3α,7α,11β-trihydroxy-6α-ethyl-...)
Affinity DataEC50:  200nMAssay Description:AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665622(US20240116912, Example 1 | 3-(4-((5-cyclopropyl-3-...)
Affinity DataEC50:  3.18E+3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665623(US20240116912, Example 2 | 4-(((1-(4-(1H-diazirin-...)
Affinity DataEC50:  2.89E+3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665624(US20240116912, Example 3 | 3-(4-(4-((5-cyclopropyl...)
Affinity DataEC50:  3.60nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665625(US20240116912, Example 4 | 4-(6-(4-((5-cyclopropyl...)
Affinity DataEC50:  220nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665626(US20240116912, Example 5 | 3-(2-(4-((5-cyclopropyl...)
Affinity DataEC50:  31nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665627(US20240116912, Example 6 | 3-(6-(4-((5-cyclopropyl...)
Affinity DataEC50:  4.40nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665628(US20240116912, Example 7 | 3-(3-(4-((5-cyclopropyl...)
Affinity DataEC50:  105nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665629(US20240116912, Example 8 | 3-(5-(4-((5-cyclopropyl...)
Affinity DataEC50:  28.1nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665630(US20240116912, Example 9 | 3-(5-(4-((5-cyclopropyl...)
Affinity DataEC50:  175nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665631(US20240116912, Example 10 | 6-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  9.10nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665632(US20240116912, Example 11 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  21.9nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665633(US20240116912, Example 12 | 5-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  73.7nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665634(US20240116912, Example 13 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  3.5nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665635(US20240116912, Example 14 | 3-(2-chloro-4-(4-((5-c...)
Affinity DataEC50:  8.5nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665636(US20240116912, Example 15 | 3-(4-(3-((5-cyclopropy...)
Affinity DataEC50:  892nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665637(US20240116912, Example 16 | 5-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  24nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665638(US20240116912, Example 17 | 2-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  6.07E+3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665639(US20240116912, Example 18 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  2.90nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665640(US20240116912, Example 19 | 3-(4-(3-((5-cyclopropy...)
Affinity DataEC50:  122nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665641(US20240116912, Example 20 | 3-(4-((2S,4R)-4-((5-cy...)
Affinity DataEC50:  114nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665642(US20240116912, Example 21 | 3-(4-((2R,4S)-4-((5-cy...)
Affinity DataEC50:  79.3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665643(US20240116912, Example 22 | 3-(4-((2S,4S)-4-((5-cy...)
Affinity DataEC50:  63.3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

Displayed 1 to 50 (of 104 total ) | Next | Last >>
Jump to: