Compile Data Set for Download or QSAR
Report error Found 96 Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D]'
LigandPNGBDBM210052(US9273046, 2.30 | US10576087, Compound 2.30)
Affinity DataIC50: 0.25nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2020
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LigandPNGBDBM210051(US9273046, 2.29 | US9895376, Compound 2.29 | US105...)
Affinity DataIC50: 0.25nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210021(US9273046, 2.27 | US9895376, Compound 2.27 | US105...)
Affinity DataIC50: 0.25nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210020(US9273046, 2.26 | US9895376, Compound 2.26 | US105...)
Affinity DataIC50: 0.25nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210037(US9273046, 2.1 | US9895376, Compound 2.1 | US10576...)
Affinity DataIC50: 0.300nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210022(US9273046, 2.31 | US9895376, Compound 2.31 | US105...)
Affinity DataIC50: 0.350nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2020
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LigandPNGBDBM210015(US9273046, 2.21 | US9895376, Compound 2.21 | US105...)
Affinity DataIC50: 0.400nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2020
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LigandPNGBDBM372977(US9895376, Compound 2.4a | US10576087, Compound 2....)
Affinity DataIC50: 0.540nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210044(US9273046, 2.4 | US9895376, Compound 2.4 | US10576...)
Affinity DataIC50: 0.560nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210024(US9273046, 2.33 | US9895376, Compound 2.33 | US105...)
Affinity DataIC50: 0.600nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210002(US9273046, 2.8 | US9895376, Compound 2.8 | US10576...)
Affinity DataIC50: 0.710nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210023(US9273046, 2.32 | US9895376, Compound 2.32 | US105...)
Affinity DataIC50: 0.900nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210016(US9273046, 2.22 | US9895376, Compound 2.22 | US105...)
Affinity DataIC50: 1nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM372967(US9895376, Compound 2.2a | US10576087, Compound 2....)
Affinity DataIC50: 1.20nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210038(US9273046, 2.2 | US9895376, Compound 2.2 | US10576...)
Affinity DataIC50: 1.40nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210034(US9273046, 1.1 | US9895376, Compound 1.1 | US10576...)
Affinity DataIC50: 1.40nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210013(US9273046, 2.19 | US9895376, Compound 2.19 | US105...)
Affinity DataIC50: 1.60nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210007(US9273046, 2.13 | US9895376, Compound 2.28 | US105...)
Affinity DataIC50: 1.70nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210001(US9273046, 2.7 | US9895376, Compound 2.7 | US10576...)
Affinity DataIC50: 2.10nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM372978(US9895376, Compound 2.4b | US10576087, Compound 2....)
Affinity DataIC50: 2.5nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM372985(US9895376, Compound 2.5b | US10576087, Compound 2....)
Affinity DataIC50: 2.5nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM372974(US9895376, Compound 2.3b | US10576087, Compound 2....)
Affinity DataIC50: 3nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210032(US9273046, 3.7 | US9895376, Compound 3.7 | US10576...)
Affinity DataIC50: 3.20nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
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LigandPNGBDBM210005(US9273046, 2.11 | US9895376, Compound 2.11 | US105...)
Affinity DataIC50: 3.30nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210009(US9273046, 2.15 | US9895376, Compound 2.15 | US105...)
Affinity DataIC50: 3.60nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210010(US9273046, 2.16 | US9895376, Compound 2.16 | US105...)
Affinity DataIC50: 3.80nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM372973(US9895376, Compound 2.3a | US10576087, Compound 2....)
Affinity DataIC50: 4nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210006(US9273046, 2.12 | US9895376, Compound 2.12 | US105...)
Affinity DataIC50: 4.10nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210025(US9273046, 2.34 | US9895376, Compound 2.34 | US105...)
Affinity DataIC50: 4.20nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210018(US9273046, 2.24 | US9895376, Compound 2.24 | US105...)
Affinity DataIC50: 4.30nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210014(US9273046, 2.20 | US9895376, Compound 2.20 | US105...)
Affinity DataIC50: 4.40nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210000(US9273046, 2.6 | US9895376, Compound 2.6 | US10576...)
Affinity DataIC50: 4.5nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210003(US9273046, 2.9 | US9895376, Compound 2.9 | US10576...)
Affinity DataIC50: 4.5nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210041(US9273046, 2.3 | US9895376, Compound 2.3 | US10576...)
Affinity DataIC50: 4.90nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210047(US9273046, 2.5 | US9895376, Compound 2.5 | US10576...)
Affinity DataIC50: 5nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210036(US9273046, 1.3 | US10576087, Compound 1.3)
Affinity DataIC50: 5.5nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210011(US9273046, 2.17 | US9895376, Compound 2.17 | US105...)
Affinity DataIC50: 5.90nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210012(US9273046, 2.18 | US9895376, Compound 2.18 | US105...)
Affinity DataIC50: 6.20nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210028(US9273046, 3.1 | US10576087, Compound 3.1)
Affinity DataIC50: 6.5nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM372968(US9895376, Compound 2.2b | US10576087, Compound 2....)
Affinity DataIC50: 8.80nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210008(US9273046, 2.14 | US9895376, Compound 2.14 | US105...)
Affinity DataIC50: 9.70nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210035(US9273046, 1.2 | US9895376, Compound 1.2 | US10576...)
Affinity DataIC50: 12nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210057(US9273046, 2.35 | US9895376, Compound 2.35 | US105...)
Affinity DataIC50: 12nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210053(US9895376, Compound 3.5 | US9273046, 3.5 | US10576...)
Affinity DataIC50: 20nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM372981(US9895376, Compound 2.5a | US10576087, Compound 2....)
Affinity DataIC50: 21nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210027(US9273046, 2.37 | US9895376, Compound 2.37 | US105...)
Affinity DataIC50: 23nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210004(US9273046, 2.10 | US9895376, Compound 2.10 | US105...)
Affinity DataIC50: 25nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210026(US9273046, 2.36 | US9895376, Compound 2.36 | US105...)
Affinity DataIC50: 32nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210017(US9273046, 2.23 | US9895376, Compound 2.23 | US105...)
Affinity DataIC50: 35nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM210019(US9273046, 2.25 | US9895376, Compound 2.25 | US105...)
Affinity DataIC50: 36nMAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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