Compile Data Set for Download or QSAR
Report error Found 117 Enz. Inhib. hit(s) with Target = 'Pyrroline-5-carboxylate reductase'
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522088(CHEMBL4442920)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522095(CHEMBL4452615)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522061(CHEMBL4462797)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522060(CHEMBL4554584)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522110(CHEMBL4440917)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522058(CHEMBL4470037)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522056(CHEMBL4442170)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522097(CHEMBL4578387)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522112(CHEMBL4538363)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522064(CHEMBL4471360)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522075(CHEMBL4449993)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522109(CHEMBL4441578)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522096(CHEMBL4441742)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522070(CHEMBL4545182)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522093(CHEMBL4566601)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522062(CHEMBL4518799)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522072(CHEMBL4521734)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522078(CHEMBL4524807)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522054(CHEMBL4471016)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522101(CHEMBL4589637)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522087(CHEMBL4531369)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487061((3,5-Dichlorophenylamino)Methylenediphosphonic Aci...)
Affinity DataIC50: 7.69E+4nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487061((3,5-Dichlorophenylamino)Methylenediphosphonic Aci...)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522057(CHEMBL4450640)
Affinity DataIC50: 9.20E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522077(CHEMBL4540573)
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522090(CHEMBL4582299)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487065(2,3-DICHLOROPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487065(2,3-DICHLOROPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487066(2,6-DICHLOROPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487066(2,6-DICHLOROPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID)
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522063(CHEMBL4572130)
Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522065(CHEMBL4460666)
Affinity DataIC50: 1.42E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522091(CHEMBL4551995)
Affinity DataIC50: 1.61E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522068(CHEMBL4441214)
Affinity DataIC50: 1.84E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50172756(N-benzyl-N-methylprop-2-yn-1-amine | Eutonyl | Ben...)
Affinity DataIC50: 1.98E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522104(CHEMBL4582778)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522069(CHEMBL4560325)
Affinity DataIC50: 2.11E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522074(CHEMBL4451218)
Affinity DataIC50: 2.28E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50442512(CHEMBL2440433)
Affinity DataIC50: 2.68E+5nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50442512(CHEMBL2440433)
Affinity DataIC50: 2.68E+5nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522092(CHEMBL4529176)
Affinity DataIC50: 2.76E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522059(CHEMBL4529927)
Affinity DataIC50: 3.11E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522094(CHEMBL4525457)
Affinity DataIC50: 3.15E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522111(CHEMBL4562371)
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522085(CHEMBL4465015)
Affinity DataIC50: 3.37E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522066(CHEMBL4471459)
Affinity DataIC50: 3.94E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522113(CHEMBL4544449)
Affinity DataIC50: 3.94E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase(Mouse-ear cress)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50165966([(2,4-Dichloro-phenylamino)-phosphono-methyl]-phos...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPyrroline-5-carboxylate reductase 1, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50522055(CHEMBL4469892)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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