Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with Target = 'Protein disulfide-isomerase A4'
TargetProtein disulfide-isomerase A4(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  58nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein disulfide-isomerase A4(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM24777(5-hydroxy-1,4-dihydronaphthalene-1,4-dione | CHEMB...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human recombinant ERp72 assessed as inhibition of E-GSH formation using Di-E-GSSG as substrate measured for 60 mins in presence of DTT ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProtein disulfide-isomerase A4(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50633548(CHEMBL5418475)
Affinity DataIC50: 4.01E+3nMAssay Description:Inhibition of human recombinant ERp72 assessed as inhibition of E-GSH formation using Di-E-GSSG as substrate measured for 60 mins in presence of DTT ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProtein disulfide-isomerase A4(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50633544(CHEMBL5399770)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of human recombinant ERp72 assessed as inhibition of E-GSH formation using Di-E-GSSG as substrate measured for 60 mins in presence of DTT ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProtein disulfide-isomerase A4(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50550835(CHEMBL4751979)
Affinity DataIC50: 3.31E+4nMAssay Description:Inhibition of PDIA4 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 1 hr and measured by insulin reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein disulfide-isomerase A4(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50550836(CHEMBL4751241)
Affinity DataIC50: 6.16E+4nMAssay Description:Inhibition of PDIA4 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 1 hr and measured by insulin reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein disulfide-isomerase A4(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50550837(CHEMBL4762045)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PDIA4 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 1 hr and measured by insulin reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed