Compile Data Set for Download or QSAR
Report error Found 4366 Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5'
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366992(CHEMBL4168754)
Affinity DataEC50:  40nMAssay Description:Inhibition of PRMT5 in human MCF7 cells assessed as skipping of Mdm4 exon 6 mRNA splicing after 72 hrs by qRT-PCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50303760((R)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-phenyl)-...)
Affinity DataEC50:  4.60E+3nMAssay Description:Inhibition of PRMT5 in human MCF7 cells assessed as reduction in symmetrically dimethylated nuclear protein level incubated for 3 days by Alexafluor-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM486478(7-chloro-4-ethyl-2-(2-hydroxy-2-((S)-1,2,3,4-tetra...)
Affinity DataEC50:  1.00E+4nMAssay Description:The PRMT5 TE assay is a biomarker assay for identifying compounds that inhibit symmetric dimethylation of arginine (SDMA) of PRMT5 substrates. This a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM486479(7-chloro-4-ethyl-2-(2-hydroxy-2-((S)-1,2,3,4-tetra...)
Affinity DataEC50:  1.00E+4nMAssay Description:The PRMT5 TE assay is a biomarker assay for identifying compounds that inhibit symmetric dimethylation of arginine (SDMA) of PRMT5 substrates. This a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM486480(7-chloro-4-ethyl-2-(2-hydroxy-2-((S)-1,2,3,4-tetra...)
Affinity DataEC50:  1.00E+4nMAssay Description:The PRMT5 TE assay is a biomarker assay for identifying compounds that inhibit symmetric dimethylation of arginine (SDMA) of PRMT5 substrates. This a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM486481(7-chloro-4-ethyl-2-(2-hydroxy-2-((S)-1,2,3,4-tetra...)
Affinity DataEC50:  1.00E+4nMAssay Description:The PRMT5 TE assay is a biomarker assay for identifying compounds that inhibit symmetric dimethylation of arginine (SDMA) of PRMT5 substrates. This a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM486482(7-((1-acetylpiperidin-4-yl)amino)-2-(2-hydroxy-2-(...)
Affinity DataEC50:  1.59E+3nMAssay Description:The PRMT5 TE assay is a biomarker assay for identifying compounds that inhibit symmetric dimethylation of arginine (SDMA) of PRMT5 substrates. This a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM486483(7-((1-acetylpiperidin-4-yl)amino)-2-(2-hydroxy-2-(...)
Affinity DataEC50:  1.00E+4nMAssay Description:The PRMT5 TE assay is a biomarker assay for identifying compounds that inhibit symmetric dimethylation of arginine (SDMA) of PRMT5 substrates. This a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM486484(7-((1-acetylpiperidin-4-yl)amino)-4-ethyl-2-(2-hyd...)
Affinity DataEC50:  682nMAssay Description:The PRMT5 TE assay is a biomarker assay for identifying compounds that inhibit symmetric dimethylation of arginine (SDMA) of PRMT5 substrates. This a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM486485(7-((1-acetylpiperidin-4-yl)amino)-4-ethyl-2-(2-hyd...)
Affinity DataEC50:  3.25E+3nMAssay Description:The PRMT5 TE assay is a biomarker assay for identifying compounds that inhibit symmetric dimethylation of arginine (SDMA) of PRMT5 substrates. This a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM486486(7-((1-acetylpiperidin-4-yl)amino)-4-ethyl-2-(2-hyd...)
Affinity DataEC50:  103nMAssay Description:The PRMT5 TE assay is a biomarker assay for identifying compounds that inhibit symmetric dimethylation of arginine (SDMA) of PRMT5 substrates. This a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM486487(7-((1-acetylpiperidin-4-yl)amino)-4-ethyl-2-(2-hyd...)
Affinity DataEC50:  1.00E+4nMAssay Description:The PRMT5 TE assay is a biomarker assay for identifying compounds that inhibit symmetric dimethylation of arginine (SDMA) of PRMT5 substrates. This a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM486488(7-((1-acetylpiperidin-4-yl)amino)-2-(2-hydroxy-2-(...)
Affinity DataEC50:  3.90E+3nMAssay Description:The PRMT5 TE assay is a biomarker assay for identifying compounds that inhibit symmetric dimethylation of arginine (SDMA) of PRMT5 substrates. This a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM486489(7-((1-acetylpiperidin-4-yl)amino)-2-(2-hydroxy-2-(...)
Affinity DataEC50:  102nMAssay Description:The PRMT5 TE assay is a biomarker assay for identifying compounds that inhibit symmetric dimethylation of arginine (SDMA) of PRMT5 substrates. This a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566321(CHEMBL4867267)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566322(CHEMBL4853705)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566323(CHEMBL4860414)
Affinity DataEC50:  0.900nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566324(CHEMBL4851358)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566325(CHEMBL4846860)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566326(CHEMBL4860893)
Affinity DataEC50:  2.30nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566327(CHEMBL4868831)
Affinity DataEC50:  4.70nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566328(CHEMBL4869259)
Affinity DataEC50:  4nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566329(CHEMBL4868773)
Affinity DataEC50:  38nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566330(CHEMBL4874774)
Affinity DataEC50: <0.5nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566331(CHEMBL4874354)
Affinity DataEC50:  2.5nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566332(CHEMBL4848739)
Affinity DataEC50:  14nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566333(CHEMBL4862310)
Affinity DataEC50: >10nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566334(CHEMBL4872775)
Affinity DataEC50:  21nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566335(CHEMBL4864483)
Affinity DataEC50:  32nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566336(CHEMBL4849067)
Affinity DataEC50:  5.30nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566337(CHEMBL4862596)
Affinity DataEC50:  9.90nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566338(CHEMBL4853843)
Affinity DataEC50:  3.20nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566339(CHEMBL4854567)
Affinity DataEC50:  5.30nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566340(CHEMBL4853251)
Affinity DataEC50:  9.90nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566341(CHEMBL4849342)
Affinity DataEC50:  3.20nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566342(CHEMBL4873952)
Affinity DataEC50:  4.60nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566343(CHEMBL4878171)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566344(CHEMBL4850190)
Affinity DataEC50:  2.80nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566345(CHEMBL4846178)
Affinity DataEC50:  2.90nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566346(CHEMBL4868904)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566347(CHEMBL4867460)
Affinity DataEC50:  0.870nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566348(CHEMBL4852843)
Affinity DataEC50:  0.890nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566349(CHEMBL4854745)
Affinity DataEC50:  0.740nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566350(CHEMBL4873949)
Affinity DataEC50:  0.970nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566351(CHEMBL4847518)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566352(CHEMBL4861625)
Affinity DataEC50:  0.840nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50566353(CHEMBL4862485)
Affinity DataEC50:  11nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM578782(US11492351, Example 1-7 | 4-(aminomethyl)-6-(1-met...)
Affinity DataKd:  1.10E+5nMAssay Description:Binding affinity to human PRMT5 assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50585592(CHEMBL5082733)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to human PRMT5 assessed as dissociation constant in presence of MTA by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 5(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM578782(US11492351, Example 1-7 | 4-(aminomethyl)-6-(1-met...)
Affinity DataKd:  5nMAssay Description:Binding affinity to human PRMT5 assessed as dissociation constant in presence of MTA by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
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