Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with Target = 'Prolyl 4-hydroxylase'
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  511nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  0.132nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50042876([2,2']Bipyridinyl-5,5'-dicarboxylic acid | CHEMBL3...)
Affinity DataIC50: 840nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM107704(US8598210, Table XV, 11 | US8598210, 119 | US87228...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50092609(CHEMBL3586252)
Affinity DataIC50: 1.20E+3nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM118338(US8653111, 62)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 2.89E+3nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50193145(Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50431015(CHEMBL2338329 | US9115085, Compound A Form A | US9...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine-2,5-dicarboxylic acid | pyr...)
Affinity DataIC50: 5.18E+3nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26113(pyridine-2,4-dicarboxylic acid | cid_10365 | pyrid...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50510124(CHEMBL3186774)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50317547(CHEMBL4163812)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine-2,5-dicarboxylic acid | pyr...)
Affinity DataIC50: 1.50E+4nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50510129(CHEMBL4475458)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM60875(GSK-J1 | 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H...)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM118339(US8653111, 72)
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000866(CHEMBL451545 | 2-(Oxalyl-amino)-propionic acid (0....)
Affinity DataIC50: 3.82E+4nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50: 4.72E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000865(CHEMBL314979 | 2-(Oxalyl-amino)-propionic acid)
Affinity DataIC50: 9.07E+4nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50510128(CHEMBL4449628)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395076(CHEMBL2164243)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158849(CHEMBL3785164)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50510125(CHEMBL4540977)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158888(CHEMBL3785984)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM14672(cid_311 | CITRIC ACID | 2-hydroxypropane-1,2,3-tri...)
Affinity DataIC50: 2.13E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50510132(CHEBI:151 | Isocitric acid)
Affinity DataIC50: 2.84E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000864(CHEMBL314175 | N-(2-Methanesulfonylamino-2-oxo-eth...)
Affinity DataIC50: 4.14E+5nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50344962((2S)-2-HYDROXYPENTANEDIOIC ACID | L-2-Hydroxygluta...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000863(CHEMBL88472 | 2-(Oxalyl-amino)-propionic acid)
Affinity DataIC50: 6.21E+5nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylase at 50 ug/mLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26122(FUMARIC ACID | Fumarate | (2E)-but-2-enedioic acid...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM23230(keto-Oxaloacetate | 2-oxobutanedioic acid | 2-Oxos...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26121(Succinic acid, 6 | butanedioic acid | Succinate | ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50510127(CHEBI:30797 | CHEMBL1234046)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50036222((1Z)-prop-1-ene-1,2,3-tricarboxylic acid | cis-aco...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM19473(2-oxopropanoic acid | 2-Oxopropanoate | Pyruvate)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50042876([2,2']Bipyridinyl-5,5'-dicarboxylic acid | CHEMBL3...)
Affinity DataKi:  140nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50092609(CHEMBL3586252)
Affinity DataKi:  200nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM107704(US8598210, Table XV, 11 | US8598210, 119 | US87228...)
Affinity DataKi:  280nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataKi:  540nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50193145(Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...)
Affinity DataKi:  710nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine-2,5-dicarboxylic acid | pyr...)
Affinity DataKi:  800nMAssay Description:Inhibitory activity against prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50431015(CHEMBL2338329 | US9115085, Compound A Form A | US9...)
Affinity DataKi:  1.07E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine-2,5-dicarboxylic acid | pyr...)
Affinity DataKi:  2.60E+3nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26113(pyridine-2,4-dicarboxylic acid | cid_10365 | pyrid...)
Affinity DataKi:  3.28E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50100861(Protocatechuic acid (M1) | Protocatechuic acid | 3...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50317547(CHEMBL4163812)
Affinity DataKi:  7.65E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
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