Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily D member 3'
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50099567(Ethanesulfonic acid (6-cyano-3-hydroxy-2,2-dimethy...)
Affinity DataIC50: 1.40E+3nMAssay Description:The inhibitory concentration for 50% was measured on potassium channel complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50235240(CHEMBL4065169)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Kv4.3 (unknown origin) assessed as reduction in transient outward potassium current by high throughput clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of Kv4.3 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50385930(CHEMBL2042163)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of KV4.3 ion channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50235250(CHEMBL4104525)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of Kv4.3 (unknown origin) assessed as reduction in transient outward potassium current by high throughput clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM328993(US9663503, Compound 1 | 5-[[4-[[(2R)-morpholin-2-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Kv4.3More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50523773(CHEMBL4475999)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50109647(Enablex | 2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-et...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50165008(2-[(1R)-3-(diisopropylamino)-1-phenylpropyl]-4-met...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50591317(CHEMBL5191783)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin) by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50625763(CHEMBL5440956)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50246769(CHEMBL4064608)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50458617(CHEMBL4215835)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human Kv4.3 expressed in CHO cells by ionworks patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50428594(CHEMBL2337981)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human Kv4.3 channel expressed in CHO cells by IONWORKS patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50524103(CHEMBL4563459)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human Kv4.3 by Ion-work electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50524101(CHEMBL4474619)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human Kv4.3 by Ion-work electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50524102(CHEMBL4542281)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human Kv4.3 by Ion-work electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50534274(CHEMBL4457557)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human Kv4.3 expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50592582(CHEMBL5204231)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50370682(SOLIFENACIN)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM84735(CAS_99200-09-6 | NSC_71301 | Nebivolol)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50088376(CHEBI:49005 | Deferasirox | Exjade | ICL670A | US1...)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50252513(9-OH-risperidone | Invega | CHEMBL1621 | 9-hydroxy...)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50088373(CHEBI:46295 | Vardenafil | cid_110634)
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023589(CHEMBL3355573)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of potassium channel Kv4.3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50395399(CHEMBL2165063)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of potassium channel Kv4.3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8125(Darunavir (DRV) | CHEMBL1323 | (3R,3aS,6aR)-hexahy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50146710(CHEMBL1111 | Letairis | (S)-2-(4,6-Dimethyl-pyrimi...)
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50160154(CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...)
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 5.01E+5nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103642(CHEMBL308954 | TMC-125 | TMC 125 | 4-(6-amino-5-br...)
Affinity DataIC50: 3.16E+6nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM86748(CAS_386750-22-7 | NSC_6918664 | O-Desmethylvenlafa...)
Affinity DataIC50: 5.01E+6nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)
Affinity DataIC50: 5.01E+6nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50088378(CHEBI:68478 | Afinitor | Afinitor Disperz | Everol...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM11162(Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...)
Affinity DataIC50: 1.00E+8nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50061306(CHEMBL1205 | Viracept | (3S,4aS,8aS)-2-[(2R,3R)-2-...)
Affinity DataIC50: 5.01E+6nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50237710(AMN 107 | AMN107 | 4-methyl-N-[3-(4-methyl-1H-imid...)
Affinity DataIC50: 3.16E+6nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033110(N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50248106(CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine)
Affinity DataIC50: 1.58E+6nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed