Compile Data Set for Download or QSAR
Report error Found 1636 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 2'
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM138355(US8877944, P1)
Affinity DataKd:  1.05E+3nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167408(US9073893, 1)
Affinity DataKd:  780nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167409(US9073893, 2)
Affinity DataKd:  1.49E+3nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167412(US9073893, 5)
Affinity DataKd:  540nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167413(US9073893, 6)
Affinity DataKd:  1.88E+3nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167414(US9073893, 7)
Affinity DataKd:  50nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167415(US9073893, 8)
Affinity DataKd:  40nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167416(US9073893, 9)
Affinity DataKd:  140nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167417(US9073893, 14)
Affinity DataKd:  30nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167420(US9073893, 20)
Affinity DataKd:  300nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167421(US9073893, 21)
Affinity DataKd:  70nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167422(US9073893, 22)
Affinity DataKd:  500nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167423(US9073893, 23)
Affinity DataKd:  5.00E+3nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240704(US9422243, 1)
Affinity DataKd:  1.03E+3nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240705(US9422243, 2)
Affinity DataKd:  1.96E+3nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240706(US9422243, 3)
Affinity DataKd:  7.20E+3nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240707(US9422243, 4)
Affinity DataKd:  240nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240708(US9422243, 5)
Affinity DataKd:  1.00E+3nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240709(US9422243, 6)
Affinity DataKd:  540nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
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TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240710(US9422243, 7)
Affinity DataKd:  1.19E+3nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110838(CHEMBL3605992)
Affinity DataKd:  118nMAssay Description:Binding affinity to recombinant human HisGST-tagged PARP-2 catalytic domain by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM138298(US8877944, 7)
Affinity DataKd:  3.94E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110836(CHEMBL3606017 | US10800739, Compound (28) | US1142...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM138325(US8877944, 29)
Affinity DataKd:  3.02E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM27135(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazo...)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to recombinant human HisGST-tagged PARP-2 catalytic domain by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataKd:  0.280nMAssay Description:Binding affinity to recombinant human HisGST-tagged PARP-2 catalytic domain by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110824(CHEMBL3605967)
Affinity DataKd:  125nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110828(CHEMBL3605974)
Affinity DataKd: <30nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110827(CHEMBL3605973 | US10800739, Compound (17) | US1142...)
Affinity DataKd:  286nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110826(CHEMBL3605972 | US10800739, Compound (2) | US11420...)
Affinity DataKd:  178nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110825(CHEMBL3605970)
Affinity DataKd:  575nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110823(CHEMBL1329044)
Affinity DataKd:  422nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110830(CHEMBL3605978)
Affinity DataKd:  3.36E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110829(CHEMBL3605976 | US10800739, Compound (15) | US1142...)
Affinity DataKd:  5.87E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM138344(US8877944, 49)
Affinity DataKd:  2.60E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM138342(US8877944, 47)
Affinity DataKd:  1.11E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110833(CHEMBL3605983 | US10800739, Compound (3) | US11420...)
Affinity DataKd:  5.78E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110832(CHEMBL3605982 | US10800739, Compound (16))
Affinity DataKd:  420nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110831(CHEMBL3605981 | US10800739, Compound (32) | US1142...)
Affinity DataKd:  670nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110837(CHEMBL3605991)
Affinity DataKd:  340nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110835(CHEMBL3605990)
Affinity DataKd:  33nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110834(CHEMBL3605986)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110840(CHEMBL3605994 | US10800739, Compound (24) | US1142...)
Affinity DataKd:  441nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110839(CHEMBL3605993)
Affinity DataKd:  264nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110838(CHEMBL3605992)
Affinity DataKd:  75nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM138318(US8877944, 22)
Affinity DataKd:  2.43E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM138317(US8877944, 21)
Affinity DataKd:  2.29E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50110841(CHEMBL3605999)
Affinity DataKd:  6.92E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM138327(US8877944, 31)
Affinity DataKd:  8.99E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM138321(US8877944, 25)
Affinity DataKd:  8.71E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
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