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Report error Found 1685 Enz. Inhib. hit(s) with Target = 'Phospholipase A2'
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50236230(ursodeoxy cholic acid | 2-((R)-4-((3R,5S,7S,8R,9S,...)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to human pancreatic recombinant 1B PLA2 expressed in Escherichia coli by resonance energy transfer assay in presence of trimethyl-am...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM21680(Cholic Acid | (R)-4-((3R,5S,7R,8R,10S,12S,13R,14S,...)
Affinity DataKd: >1.50E+5nMAssay Description:Binding affinity to human pancreatic recombinant 1B PLA2 expressed in Escherichia coli by resonance energy transfer assay in presence of trimethyl-am...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50029031(CHEMBL223344 | 1-Amino-4-{4-[4-chloro-6-(3-sulfo-p...)
Affinity DataEC50:  6.43E+3nMAssay Description:Antagonist activity at rat PA2 transfected in xenopus oocyte cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.93E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740623(US20250154153, Compound 1218-40)
Affinity DataIC50: 0.120nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740621(US20250154153, Compound 1218-20S)
Affinity DataIC50: 0.141nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740619(US20250154153, Compound 1218-39)
Affinity DataIC50: 0.191nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740628(US20250154153, Compound 1109-51)
Affinity DataIC50: 0.191nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740622(US20250154153, Compound 1218-20R)
Affinity DataIC50: 0.209nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740620(US20250154153, Compound 1218-20)
Affinity DataIC50: 0.219nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740622(US20250154153, Compound 1218-20R)
Affinity DataIC50: 0.269nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740621(US20250154153, Compound 1218-20S)
Affinity DataIC50: 0.282nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740629(US20250154153, Compound 1109-52)
Affinity DataIC50: 0.282nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740620(US20250154153, Compound 1218-20)
Affinity DataIC50: 0.288nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740632(US20250154153, Compound 1109-55S)
Affinity DataIC50: 0.288nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740619(US20250154153, Compound 1218-39)
Affinity DataIC50: 0.398nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740627(US20250154153, Compound 1109-14)
Affinity DataIC50: 0.427nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740625(US20250154153, Compound 1218-4B)
Affinity DataIC50: 0.525nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740626(US20250154153, Compound 1109-15)
Affinity DataIC50: 0.603nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740624(US20250154153, Compound 1218-4A)
Affinity DataIC50: 0.617nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740626(US20250154153, Compound 1109-15)
Affinity DataIC50: 0.708nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740632(US20250154153, Compound 1109-55S)
Affinity DataIC50: 0.724nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740623(US20250154153, Compound 1218-40)
Affinity DataIC50: 0.794nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740630(US20250154153, Compound 1109-52S)
Affinity DataIC50: 1.07nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740628(US20250154153, Compound 1109-51)
Affinity DataIC50: 1.29nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053109([1-Aminooxalyl-3-(2-benzyl-benzyl)-2-ethyl-indoliz...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053136((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-methyl-indo...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50601469(CHEMBL5172164)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human group IIA phospholipase A2 preincubated with compound for 10 mins followed by enzyme addition and measured after 30 mins by PC/DO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740625(US20250154153, Compound 1218-4B)
Affinity DataIC50: 1.41nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740629(US20250154153, Compound 1109-52)
Affinity DataIC50: 1.51nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740624(US20250154153, Compound 1218-4A)
Affinity DataIC50: 1.82nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740631(US20250154153, Compound 1109-55)
Affinity DataIC50: 1.91nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740630(US20250154153, Compound 1109-52S)
Affinity DataIC50: 2.14nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740627(US20250154153, Compound 1109-14)
Affinity DataIC50: 2.29nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053106([1-Aminooxalyl-2-ethyl-3-(3-trifluoromethyl-benzyl...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055367([3-Aminooxalyl-1-(3-chloro-benzyl)-2-ethyl-1H-indo...)
Affinity DataIC50: 3nMAssay Description:Compound was tested for inhibition of porcine secreted pancreatic PLA2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055371((3-aminooxalyl-1-biphenyl-2-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053108((1-Aminooxalyl-3-benzyl-2-methyl-indolizin-8-yloxy...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053137((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indol...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053102([1-Aminooxalyl-3-(3-chloro-benzyl)-2-ethyl-indoliz...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50161301(2-[4-(2-Benzenesulfonylamino-2-oxo-ethoxy)-1-benzy...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50053137((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indol...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human group IIA phospholipase A2 preincubated with compound for 10 mins followed by enzyme addition and measured after 30 mins by PC/DO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055374([3-Aminooxalyl-1-(2-benzyl-benzyl)-2-ethyl-1H-indo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055374([3-Aminooxalyl-1-(2-benzyl-benzyl)-2-ethyl-1H-indo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50161305((3-Aminooxalyl-1-cyclohexylmethyl-2-methyl-2,3-dih...)
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053114((1-Aminooxalyl-3-biphenyl-3-ylmethyl-2-ethyl-indol...)
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053133((1-Aminooxalyl-3-benzyl-2-ethyl-indolizin-8-yloxy)...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053096([1-Aminooxalyl-3-(4-butyl-benzyl)-2-ethyl-indolizi...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053123((1-Aminooxalyl-2-ethyl-3-naphthalen-1-ylmethyl-ind...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50601472(CHEMBL5208632)
Affinity DataIC50: 5nMAssay Description:Inhibition of human group IIA phospholipase A2 preincubated with compound for 10 mins followed by enzyme addition and measured after 30 mins by PC/DO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
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