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Report error Found 131 Enz. Inhib. hit(s) with Target = 'Pantothenate kinase'
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071513(CHEMBL3410240)
Affinity DataEC50:  2.41E+3nMAssay Description:Activation of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071514(CHEMBL3410241)
Affinity DataEC50:  1.51E+3nMAssay Description:Activation of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071548(CHEMBL3410242)
Affinity DataEC50:  1.72E+3nMAssay Description:Activation of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071569(CHEMBL3410243)
Affinity DataEC50:  3.43E+3nMAssay Description:Activation of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586918(CHEMBL5082138)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50155166(4-(6-Chloro-pyridazin-3-yl)-piperazine-1-carboxyli...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586917(CHEMBL5077276)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586915(CHEMBL5094733)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM649476(US11891378, Example 6)
Affinity DataIC50: 2.20nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM649472(US11891378, Example 2)
Affinity DataIC50: 2.90nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM649480(US11891378, Example 10)
Affinity DataIC50: 3.80nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586916(CHEMBL5078496)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM649479(US11891378, Example 9)
Affinity DataIC50: 5.20nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM649477(US11891378, Example 7)
Affinity DataIC50: 5.80nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM649473(US11891378, Example 3)
Affinity DataIC50: 6.5nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM649475(US11891378, Example 5)
Affinity DataIC50: 6.90nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM649471(US11891378, Example 1)
Affinity DataIC50: 8.90nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586913(CHEMBL5085732)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586920(CHEMBL5082695)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM649474(US11891378, Example 4)
Affinity DataIC50: 12.5nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM649478(US11891378, Example 8)
Affinity DataIC50: 12.9nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586901(CHEMBL5093027)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071456(CHEMBL3410246)
Affinity DataIC50: 25nMAssay Description:Inhibition of purified human Pank3 using d-[1-14C]pantothenate as substrate after 10 mins by radiochemical enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586914(CHEMBL5075383)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Uppsala University

LigandPNGBDBM188493(Triazole 1e)
Affinity DataIC50: 50nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586874(CHEMBL5078248)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586896(CHEMBL5092780)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071456(CHEMBL3410246)
Affinity DataIC50: 70nMAssay Description:Inhibition of purified human Pank1beta using d-[1-14C]pantothenate as substrate after 10 mins by radiochemical enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Uppsala University

LigandPNGBDBM188489(Triazole 1a)
Affinity DataIC50: 90nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2016
Entry Details Article
PubMed
TargetPantothenate kinase 2, mitochondrial(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071456(CHEMBL3410246)
Affinity DataIC50: 92nMAssay Description:Inhibition of purified human Pank2 using d-[1-14C]pantothenate as substrate after 10 mins by radiochemical enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Uppsala University

LigandPNGBDBM188495(Biaryl 2a)
Affinity DataIC50: 120nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071455(CHEMBL3410245)
Affinity DataIC50: 120nMAssay Description:Inhibition of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Uppsala University

LigandPNGBDBM188495(Biaryl 2a)
Affinity DataIC50: 130nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2016
Entry Details Article
PubMed
TargetPantothenate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Uppsala University

LigandPNGBDBM188492(Triazole 1d)
Affinity DataIC50: 140nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2016
Entry Details Article
PubMed
TargetPantothenate kinase 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071456(CHEMBL3410246)
Affinity DataIC50: 140nMAssay Description:Inhibition of Pank1beta (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 1, putative(Plasmodium falciparum (isolate 3D7))
The Australian National University

Curated by ChEMBL
LigandPNGBDBM50285608(CHEMBL4167606)
Affinity DataIC50: 140nMAssay Description:Inhibition of pantothenate kinase in Plasmodium falciparum 3D7 trophozoites using [14C]pantothenate as substrate after 15 mins by TopCount scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2020
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586909(CHEMBL5088913)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Uppsala University

LigandPNGBDBM188491(Triazole 1c)
Affinity DataIC50: 150nMAssay Description:Briefly, MtPanK activity was measured in a pyruvate kinaselactate dehydrogenase-coupled assay where the reaction rate was determined by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586910(CHEMBL5088098)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586912(CHEMBL5092773)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071454(CHEMBL3410244)
Affinity DataIC50: 180nMAssay Description:Inhibition of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071449(CHEMBL3410398)
Affinity DataIC50: 190nMAssay Description:Inhibition of Pank1beta (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586872(CHEMBL5073319)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586903(CHEMBL5076791)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586904(CHEMBL5070550)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586900(CHEMBL5079891)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071469(CHEMBL3410256)
Affinity DataIC50: 240nMAssay Description:Inhibition of Pank1beta (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50586911(CHEMBL5086917)
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071382(CHEMBL1555019)
Affinity DataIC50: 280nMAssay Description:Inhibition of Pank1beta (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071453(CHEMBL3410400)
Affinity DataIC50: 350nMAssay Description:Inhibition of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
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