Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'POU domain, class 2, transcription factor 1'
TargetPOU domain, class 2, transcription factor 1(Human)
Nippon Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50228403(8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-yn-1-yl-3-m...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of OCT1 (unknown origin) expressed in HEK293 cells assessed as reduction of [14C]metformin substrate uptake at 100 uM by liquid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetPOU domain, class 2, transcription factor 1(Human)
Nippon Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50228403(8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-yn-1-yl-3-m...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of OCT1 (unknown origin) expressed in HEK293 cells assessed as reduction of [ethyl 1-14C]TEA substrate uptake at 100 uM by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetPOU domain, class 2, transcription factor 1(Human)
Nippon Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of OCT1 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed