Compile Data Set for Download or QSAR
Report error Found 363 Enz. Inhib. hit(s) with Target = 'PAS domain-containing serine/threonine-protein kinase [879-1323]'
LigandPNGBDBM474989(US10849901, Compound 39 | US10953012, Example 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487173(2-(4-Chloro-phenyl)-5-methyl-4H-pyrazolo[1,5-a]pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487174(6-Benzyl-3-(4-chloro-phenyl)-5-methyl-4H-pyrazolo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487175(2-(3-Bromo-phenyl)-5-methyl-4H-pyrazolo[1,5-a]pyri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487176(2-Benzyl-3-(4-methoxy-phenyl)-5-phenyl-4H-pyrazolo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487177(US10953012, Example 20 | 3-(4-Methoxy-phenyl)-2-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM475045(US10849901, Compound 95 | US10953012, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487179(3-(4-Chloro-phenyl)-2-methyl-5-phenyl-4H-pyrazolo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM50168142(CHEMBL3716578 | US10849901, Compound 38 | US109530...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM474979(US10849901, Compound 29 | US10953012, Example 25)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487184(2-Benzyl-3-naphthalen-1-yl-5-phenyl-4H-pyrazolo[1,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487185(2-(4-Methoxy-benzyl)-3,5-diphenyl-4H-pyrazolo[1,5-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487186(2-Methyl-7-oxo-3,5-diphenyl-4,7-dihydro-pyrazolo[1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487187(5-(4-Methoxy-phenyl)-2-methyl-3-phenyl-4H-pyrazolo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487188(3-(4-Fluoro-phenyl)-2-methyl-5-phenyl-4H-pyrazolo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM50260215(CHEMBL3717926 | US10953012, Example 16)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487191(5-(4-Chloro-phenyl)-2-methyl-3-phenyl-4H-pyrazolo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487192(2-Benzyl-3-(4-chloro-phenyl)-5-propyl-4H-pyrazolo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487193(2-Benzyl-5-methoxymethyl-3-(4-methoxy-phenyl)-4H-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487196(3-(4-Chloro-phenyl)-2-methyl-5-propyl-4H-pyrazolo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487177(US10953012, Example 20 | 3-(4-Methoxy-phenyl)-2-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487195(2,5-Dibenzyl-3-phenyl-4H-pyrazolo[1,5-a]pyrimidin-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487197(5-Benzyl-3-(4-methoxy-phenyl)-2-methyl-4H-pyrazolo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487198(2-Benzyl-3-(4-chloro-phenyl)-5-methoxymethyl-4H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM474979(US10849901, Compound 29 | US10953012, Example 25)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487200(2-Benzyl-3-(4-chlorophenyl)-6,7-dihydro-4H-cyclope...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487201(3-(4-Chlorophenyl)-2-methyl-6,7-dihydro-4H-cyclope...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487202(3-(4-Chloro-phenyl)-2,5-dimethyl-4H-pyrazolo[1,5-a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487203(2-(4-Chloro-phenyl)-5-methoxymethyl-4H-pyrazolo[1,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487204(5-Isopropyl-2-(4-methoxy-phenyl)-3-phenyl-4H-pyraz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487205(2-(4-Methoxy-benzyl)-5-methyl-3-phenyl-4H-pyrazolo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487206(6-Ethyl-2-(4-methoxy-benzyl)-5-methyl-3-phenyl-4H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487207(3-(4-Chloro-phenyl)-6-ethyl-2,5-dimethyl-4H-pyrazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM475039(US10849901, Compound 89 | US10953012, Example 34)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487209(2,3-Diphenyl-6,7-dihydro-4H-cyclopenta[d]pyrazolo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487210((7-oxo-2,3-diphenyl-4,7-dihydro-pyrazolo[1,5-a]pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487215(2-Methyl-3-phenyl-5-p-tolyl-4H-pyrazolo[1,5-a]pyri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487216(3-(4-Fluoro-phenyl)-5-(4-methoxy-phenyl)-2-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487175(2-(3-Bromo-phenyl)-5-methyl-4H-pyrazolo[1,5-a]pyri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487219(5-(4-Methoxyphenyl)-2-methyl-3-propylpyrazolo[1,5-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487220(5-(4-Methoxyphenyl)-3-(pyridin-3-yl)pyrazolo[1,5-a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487221(3-Benzyl-2-methyl-5-(quinolin-6-yl)pyrazolo[1,5-a]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487222(3-Benzyl-5-(1H-indol-6-yl)-2-methylpyrazolo[1,5-a]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487223(3-(3-Chlorobenzyl)-5-(benzo[d][1,3]dioxol-5-yl)-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487224(3-(4-Chlorobenzyl)-5-(benzo[d][1,3]dioxol-5-yl)-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487225(3-(4-Fluorophenyl)-2-methyl-5-(pyridin-3-yl)pyrazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487226(3-(4-Fluorophenyl)-5-(pyridin-2-yl)pyrazolo[1,5-a]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487227(5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-(4-fluor...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487228(5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-(3-metho...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM487229(US10953012, Example 149 | 5-(Benzofuran-2-yl)-3-(p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent

Displayed 1 to 50 (of 363 total ) | Next | Last >>
Jump to: