Compile Data Set for Download or QSAR
Report error Found 355 Enz. Inhib. hit(s) with Target = 'Oligo-1,6-glucosidase IMA1'
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM108221(5-(hydroxymethyl)-2-[3-(4-phenylphenyl)propyl]- 5H...)
Affinity DataIC50: 6nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM108222(2-[3-(4-cyclohexylphenyl)propyl]-5-(hydroxymethyl)...)
Affinity DataIC50: 52nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM60585(2-(3'-Fluorophenyl)-7-methyl-1H-benzo[d]imidazole ...)
Affinity DataIC50: 165nMAssay Description:The 135 µL of 50 mM phosphate saline buffer pH (6.8), solution of enzyme (20 µL), and 20 µL of test sample with 70% DMSO was added to 96-well plate. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM108219(5-(hydroxymethyl)-2-[3-(4-methylphenyl)propyl]- 5H...)
Affinity DataIC50: 280nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM108220(5-(hydroxymethyl)-2-[3-(4-methoxyphenyl)propyl]- 5...)
Affinity DataIC50: 300nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM108216(5-(hydroxymethyl)-2-(2-phenylethyl)-5H,6H,7H,8H- i...)
Affinity DataIC50: 570nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM108223(2-[3-(4-fluorophenyl)propyl]-5-(hydroxymethyl)- 5H...)
Affinity DataIC50: 730nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM108218(5-(hydroxymethyl)-2-octyl-5H,6H,7H,8H-imidazo[1,2-...)
Affinity DataIC50: 970nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM108224(N-phenyl-4-[6,7,8-trihydroxy-5-(hydroxymethyl)- 5H...)
Affinity DataIC50: 1.05E+3nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM178004(BDBM178006 | 2-(3-((3-(trifluoromethyl)benzyl)oxy)...)
Affinity DataIC50: 1.26E+3nMpH: 6.8Assay Description:The alpha-glucosidase inhibition assay had been carried out using baker's yeast alpha-glucosidase (EC 3.2.1.20) and p-nitrophenyl-alpha-D-glucopyrano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM50438504(CHEMBL2414818)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM173530((E)-N'-(3,4,5-trihydroxybenzylidene)-1H-indole...)
Affinity DataIC50: 2.30E+3nMAssay Description:The 135 µL of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 µL of test sample with 70% DMSO added into the wells. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM150768(2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-1-(3-h...)
Affinity DataIC50: 2.46E+3nMT: 2°CAssay Description:Typically, α-glucosidase activity was assayed in 50 mM phosphate buffer (pH 6.8) containing 5% v/v DMSO and PNP glycoside was used as a substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2015
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM222221(3-(4-(4,5-diphenyl-1H-imidazol-2-yl)-1-phenyl-1H-p...)
Affinity DataIC50: 2.78E+3nMAssay Description:At 37 °C, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM222222(6-Bromo-3-(4-(4,5-diphenyl-1H-imidazol-2-yl)-1-phe...)
Affinity DataIC50: 2.95E+3nMAssay Description:At 37 °C, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM108217(2-(3,3-dimethylbutyl)-5-(hydroxymethyl)- 5H,6H,7H,...)
Affinity DataIC50: 3.42E+3nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM178010(2-(3-((2,3-difluorobenzyl)oxy)phenyl)-4H-chromen-4...)
Affinity DataIC50: 3.49E+3nMpH: 6.8Assay Description:The alpha-glucosidase inhibition assay had been carried out using baker's yeast alpha-glucosidase (EC 3.2.1.20) and p-nitrophenyl-alpha-D-glucopyrano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM50063756(CHEMBL3397482)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM179781(2-(2'-Chlorophenyl)-7-methyl-1H-benzo[d]imidaz...)
Affinity DataIC50: 5.30E+3nMAssay Description:The 135 µL of 50 mM phosphate saline buffer pH (6.8), solution of enzyme (20 µL), and 20 µL of test sample with 70% DMSO was added to 96-well plate. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM178004(BDBM178006 | 2-(3-((3-(trifluoromethyl)benzyl)oxy)...)
Affinity DataIC50: 5.45E+3nMpH: 6.8Assay Description:The alpha-glucosidase inhibition assay had been carried out using baker's yeast alpha-glucosidase (EC 3.2.1.20) and p-nitrophenyl-alpha-D-glucopyrano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM50438503(CHEMBL2414819)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM222219(4-(4,5-Diphenyl-1H-imidazol-2-yl)-1-(4-nitrophenyl...)
Affinity DataIC50: 7.81E+3nMAssay Description:At 37 °C, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM175324((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Affinity DataIC50: 8.40E+3nMpH: 6.8Assay Description:The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM175315((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Affinity DataIC50: 8.44E+3nMpH: 6.8Assay Description:The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM175317((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Affinity DataIC50: 8.44E+3nMpH: 6.8Assay Description:The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM178007(2-(3-((3-((trifluoromethyl)thio)benzyl)oxy)phenyl)...)
Affinity DataIC50: 8.66E+3nMpH: 6.8Assay Description:The alpha-glucosidase inhibition assay had been carried out using baker's yeast alpha-glucosidase (EC 3.2.1.20) and p-nitrophenyl-alpha-D-glucopyrano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM175309((E)-N'-(2,5-dihydroxybenzylidene)-4-(5,6-dimet...)
Affinity DataIC50: 8.74E+3nMpH: 6.8Assay Description:The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM175311((E)-N'-(2,4-dihydroxybenzylidene)-4-(5,6-dimet...)
Affinity DataIC50: 8.74E+3nMpH: 6.8Assay Description:The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50: 9.37E+3nMAssay Description:α-Glucosidase inhibitory activity was evaluated at 37 °C, by using 0.1M phosphatebuffer (pH6.8) [28]. The enzyme(EC3.2.1.20, Saccharomyces cerev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM175310((E)-N'-(2,3-dihydroxybenzylidene)-4-(5,6-dimet...)
Affinity DataIC50: 9.99E+3nMpH: 6.8Assay Description:The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM222214(3-(4-Bromophenyl)-4-(4,5-diphenyl-1H-imidazol-2-yl...)
Affinity DataIC50: 1.20E+4nMAssay Description:At 37 °C, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM50063761(CHEMBL3397478)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM175312((E)-N'-(3,4-dihydroxybenzylidene)-4-(5,6-dimet...)
Affinity DataIC50: 1.25E+4nMpH: 6.8Assay Description:The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM108225(2,2-dimethyl-N-phenyl-5-[6,7,8-trihydroxy-5- (hydr...)
Affinity DataIC50: 1.28E+4nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM222217(4-(4,5-Diphenyl-1H-imidazol-2-yl)-3-(3-nitrophenyl...)
Affinity DataIC50: 1.28E+4nMAssay Description:At 37 °C, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM222213(3-(4-Chlorophenyl)-4-(4,5-diphenyl-1H-imidazol-2-y...)
Affinity DataIC50: 1.32E+4nMAssay Description:At 37 °C, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM173549(1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)p...)
Affinity DataIC50: 1.35E+4nMpH: 6.8 T: 2°CAssay Description:The enzyme inhibition was evaluated according to the method previously reported by Taha et al. with slight modification. Various concentration of tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM175329((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Affinity DataIC50: 1.51E+4nMpH: 6.8Assay Description:The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM50203367(CHEMBL3891396)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 15 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM50063760(CHEMBL3397479)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM50063757(CHEMBL3397481)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM179777(2-(2'-Hydroxyphenyl)-7-methyl-1H-benzo[d]imida...)
Affinity DataIC50: 1.61E+4nMAssay Description:The 135 µL of 50 mM phosphate saline buffer pH (6.8), solution of enzyme (20 µL), and 20 µL of test sample with 70% DMSO was added to 96-well plate. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM50203410(CHEMBL3901489)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 15 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM222218(3-([1,1'-Biphenyl]-4-yl)-4-(4,5-diphenyl-1H-im...)
Affinity DataIC50: 1.75E+4nMAssay Description:At 37 °C, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM175320((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Affinity DataIC50: 1.82E+4nMpH: 6.8Assay Description:The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM152619((E)-2,6-Di-t-butyl-4-((2-(4-(4-Chlorophenyl)thiazo...)
Affinity DataIC50: 1.82E+4nMpH: 6.8Assay Description:Total volume of 100 µL reaction mixture contained 70 µL 50 mM phosphate buffer pH 6.8, 10 µL test compound (0.5 mM in methanol) followed by the addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM50445973(CHEMBL3103095)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 mins measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM175321((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Affinity DataIC50: 1.83E+4nMpH: 6.8Assay Description:The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM222282(N-(3-Chlorophenyl)-6-(3,5-dimethyl-4-nitro-1H-pyra...)
Affinity DataIC50: 1.93E+4nMpH: 6.8 T: 2°CAssay Description:The enzyme assays were done in the initial linear parts of the assay curve with suitable positive and negative controls (data not shown). A total of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Nankai University

LigandPNGBDBM175330((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Affinity DataIC50: 1.94E+4nMpH: 6.8Assay Description:The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
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