Report error Found 136 Enz. Inhib. hit(s) with Target = 'Nuclear receptor subfamily 2 group E member 1'
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 7.40E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 1.94E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 6.70E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 3.20E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 4.70E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 4.00E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 7.20E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 8.30E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 5.20E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 5.00E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 3.20E+4nMAssay Description:Agonist activity at full length TLX activating element expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as dec...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TAE expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as renilla luciferase reporter activi...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 4.30E+4nMAssay Description:Agonist activity at TAE expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as renilla luciferase reporter activi...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TAE expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as renilla luciferase reporter activi...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 3.70E+4nMAssay Description:Agonist activity at TAE expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as renilla luciferase reporter activi...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataKd: 500nMAssay Description:Binding affinity to TLX LBD expressed in His6-tagged Escherichia coli Rosetta assessed as binding constant measured after 300 sec at 200 mM by isothe...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 2.00E+4nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 1.10E+4nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 1.20E+3nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 251nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 2.00E+4nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 250nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Agonist activity at human full length Gal4-fused TLX transfected in human HEK293T cells coexpressing pFR-TAE-Luc assessed as repressor activity of re...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataKd: 1.60E+3nMAssay Description:Binding affinity to recombinant TLX LBD (unknown origin) by differential scanning fluorometryMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Agonist activity at TLX (unknown origin) assessed as induction of receptor oligomerization using sGFP-labeled TLX LBD as acceptor and biotin TLX LBD ...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0510nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.102nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0280nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0300nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0850nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0640nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0280nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0300nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0360nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0670nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0140nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0140nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0190nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0130nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0130nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0340nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0280nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.0530nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 0.00600nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 6.91E+3nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair

































