Compile Data Set for Download or QSAR
Report error Found 67 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2 [888-1187]'
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726096([3a(4)Z]-6,9,15,16-tetramethyl- 9,10,11,12-tetrahy...)
Affinity DataKd:  220nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726097([3a(4)Z]-6,9,15,16-tetramethyl- 10,11,13,15-tetrah...)
Affinity DataKd:  1.20nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726098([3a(4)Z,10R]-20-chloro-6,10,15- trimethyl-10,11,13...)
Affinity DataKd:  3nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726099([3a(4)Z,10R]-20-chloro-10,15-dimethyl- 10,11,13,15...)
Affinity DataKd:  1.90nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726108([3a(4)Z,10R]-20-fluoro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  1nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726100([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  0.180nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726101([3a(4)Z,10S]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  2.5nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726102([3a(4)Z]-20-chloro-6,9,15-trimethyl- 10,11,13,15-t...)
Affinity DataKd:  0.510nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726103([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  170nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726104([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  1nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726107([3a(4)Z,10R]-20-chloro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd:  1.30nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726106([3a(4)Z,10R]-20-fluoro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd:  3.40nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726105([3a(4)Z,10R]-6,9,10,15-tetramethyl-3,8- dioxo-3,5,...)
Affinity DataKd:  46nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)
Affinity DataIC50: 2nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)
Affinity DataIC50: 2nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataIC50: 6nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataIC50: 6nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50021656(LY-3009104 | INCB-028050 | BARICITINIB | US1011290...)
Affinity DataIC50: 30nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50311017(N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyri...)
Affinity DataIC50: 30nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50021656(LY-3009104 | INCB-028050 | BARICITINIB | US1011290...)
Affinity DataIC50: 30nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50311017(N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyri...)
Affinity DataIC50: 30nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM294916(US10112907, Example 00027 | US10206907, Compound 1...)
Affinity DataIC50: 110nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM147644(US8962608, 25-24 | US8962608, 25-5 | US10766894, C...)
Affinity DataIC50: 110nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM294912(US10112907, Example 00021)
Affinity DataIC50: 110nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM294916(US10112907, Example 00027 | US10206907, Compound 1...)
Affinity DataIC50: 110nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM462294(US10766894, Compound TABLE 1.11 | US11203595, TABL...)
Affinity DataIC50: 120nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM294915(US10112907, Example 00026)
Affinity DataIC50: 120nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM410174(US10370375, Example 22)
Affinity DataIC50: 130nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50402074(CHEMBL2206059 | US10112907, Example 00024 | US1076...)
Affinity DataIC50: 140nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50402074(CHEMBL2206059 | US10112907, Example 00024 | US1076...)
Affinity DataIC50: 140nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 230nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 230nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 310nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 310nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM410170(US10370375, Example 18)
Affinity DataIC50: 390nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM103727(US8563545, 1 | US10112907, Example 00033 | US10206...)
Affinity DataIC50: 780nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM103727(US8563545, 1 | US10112907, Example 00033 | US10206...)
Affinity DataIC50: 780nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM410178(US10370375, Example 26)
Affinity DataIC50: 840nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM410177(US10370375, Example 25)
Affinity DataIC50: 1.10E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50021655(VRT-831509 | VX-509 | DECERNOTINIB | US10112907, E...)
Affinity DataIC50: 1.50E+3nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM50021655(VRT-831509 | VX-509 | DECERNOTINIB | US10112907, E...)
Affinity DataIC50: 1.50E+3nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM147692(US8962608, 28-1 | US10112907, Example 00025)
Affinity DataIC50: 1.80E+3nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM462293(US10766894, Compound TABLE 1.10 | US11203595, TABL...)
Affinity DataIC50: 1.80E+3nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM410180(US10370375, Example 28)
Affinity DataIC50: 3.20E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM410154(US10370375, Example 2)
Affinity DataIC50: 4.59E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM410153(US10370375, Example 1)
Affinity DataIC50: 5.51E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM410165(US10370375, Example 13)
Affinity DataIC50: 6.00E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM410179(US10370375, Example 27)
Affinity DataIC50: 7.80E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM410176(US10370375, Example 24)
Affinity DataIC50: 8.50E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM410161(US10370375, Example 9)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

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