Compile Data Set for Download or QSAR
Report error Found 2513 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, inducible'
LigandPNGBDBM29236(quinolinone, 7)
Affinity DataEC50:  1.30E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29237(quinolinone, 8)
Affinity DataEC50:  1.10E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29238(quinolinone, 9)
Affinity DataEC50:  500nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29239(quinolinone, 10)
Affinity DataEC50:  200nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29240(quinolinone, 11)
Affinity DataEC50:  1.30E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29241(quinolinone, 12)
Affinity DataEC50:  11nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29242(quinolinone, 13)
Affinity DataEC50:  240nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29243(quinolinone, 14)
Affinity DataEC50:  62nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29244(quinolinone, 15)
Affinity DataEC50:  56nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29245(quinolinone, 16)
Affinity DataEC50:  100nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29246(quinolinone, 17)
Affinity DataEC50:  990nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29247(quinolinone, 18)
Affinity DataEC50:  53nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29248(quinolinone, 19)
Affinity DataEC50:  350nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29249(quinolinone, 20)
Affinity DataEC50:  89nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29250(quinolinone, 21)
Affinity DataEC50:  49nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29251(quinolinone, 22)
Affinity DataEC50:  420nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29252(quinolinone, 23)
Affinity DataEC50:  9nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29253(quinolinone, 24)
Affinity DataEC50:  16nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29254(quinolinone, 25)
Affinity DataEC50:  770nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29255(quinolinone, 26)
Affinity DataEC50:  160nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29256(pyridinone, 27)
Affinity DataEC50: >1.00E+5nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29257(tetrahydroquinolinone, 28)
Affinity DataEC50:  1.14E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29258(coumarin, 29)
Affinity DataEC50:  2.00E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29259(quinoline, 30)
Affinity DataEC50: >1.00E+5nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29260(quinolinone, 31)
Affinity DataEC50: >1.00E+5nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29261(quinolinone, 36)
Affinity DataEC50:  1.30E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29262(quinoline, 32)
Affinity DataEC50: >1.00E+5nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29263(8-fluoroisoquinoline, 33)
Affinity DataEC50:  760nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29264(isoquinoline N-oxide, 34)
Affinity DataEC50:  87nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29265(quinolinone, 35)
Affinity DataEC50:  170nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29267(quinolinone, 37)
Affinity DataEC50:  53nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29268(quinolinone, 38)
Affinity DataEC50:  300nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29269(quinolinone, 39)
Affinity DataEC50:  500nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29270(quinolinone, 40)
Affinity DataEC50:  2nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29271(quinolinone, 41)
Affinity DataEC50:  11nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29272(quinolinone, 42)
Affinity DataEC50:  3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29273(quinolinone, 43)
Affinity DataEC50:  3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29274(quinolinone, 44)
Affinity DataEC50:  26nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29275(difluorocoumarin, 45)
Affinity DataEC50:  840nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29276(isoquinoline, 46)
Affinity DataEC50:  200nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM29266(isoquinoline N-oxide, 47)
Affinity DataEC50:  19nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  1.19E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50077251((2S)-2-amino-5-{[(1Z)-hydrazino(methylthio)methyle...)
Affinity DataEC50:  1.80E+5nMAssay Description:Effective concentration against NADPH oxidase activity of iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50077250((2S)-2-amino-5-{[(1Z)-(hydroxyamino)(methylthio)me...)
Affinity DataEC50:  6.60E+3nMAssay Description:Effective concentration against NADPH oxidase activity of iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50077252((2S)-2-amino-5-[(hydrazinocarbonothioyl)amino]pent...)
Affinity DataEC50:  1.90E+5nMAssay Description:Effective concentration against NADPH oxidase activity of iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)
Affinity DataKd: >4.00E+4nMAssay Description:Binding affinity to human recombinant iNOS delta 65 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)
Affinity DataKd:  630nMAssay Description:Binding affinity to human recombinant iNOS delta 65 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
LigandPNGBDBM50266727(4,4-Difluoro-L-arginine | CHEMBL476416)
Affinity DataKd:  3.10E+6nMAssay Description:Binding affinity to iNOS with heme domain construct assessed as spectral binding constant by spectral assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266728(4,4-difluoro-N(gamma)-hydroxy-L-arginine | CHEMBL4...)
Affinity DataKd:  1.16E+5nMAssay Description:Binding affinity to iNOS with heme domain construct assessed as spectral binding constant by spectral assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM21959(CHEMBL1485 | (2S)-2-amino-5-carbamimidamidopentano...)
Affinity DataKd:  7.00E+3nMAssay Description:Binding affinity to iNOS with heme domain construct assessed as spectral binding constant by spectral assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 2513 total ) | Next | Last >>
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