Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, brain [D597N,M336V]'
TargetNitric oxide synthase, brain [D597N,M336V](Rat)
University of California Irvine

LigandPNGBDBM29234(CHEMBL481815 | aminopyridine-pyrrolidine, 6 | US90...)
Affinity DataKi:  1.20E+3nM ΔG°:  -34.4kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain [D597N,M336V](Rat)
University of California Irvine

LigandPNGBDBM29235(aminopyridine-pyrrolidine, 7)
Affinity DataKi:  6.10E+3nM ΔG°:  -30.3kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain [D597N,M336V](Rat)
University of California Irvine

LigandPNGBDBM29233(CHEMBL508014 | aminopyridine-pyrrolidine, 5)
Affinity DataKi:  3.67E+4nM ΔG°:  -25.7kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain [D597N,M336V](Rat)
University of California Irvine

LigandPNGBDBM29232(3-({(3S,4S)-4-[(6-aminopyridin-2-yl)methyl]pyrroli...)
Affinity DataKi:  4.92E+4nM ΔG°:  -25.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed