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Report error Found 2607 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, brain'
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29236(quinolinone, 7)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29237(quinolinone, 8)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29238(quinolinone, 9)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29239(quinolinone, 10)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29240(quinolinone, 11)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29241(quinolinone, 12)
Affinity DataEC50:  2.30E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29242(quinolinone, 13)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29244(quinolinone, 15)
Affinity DataEC50:  2.70E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29245(quinolinone, 16)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29246(quinolinone, 17)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29248(quinolinone, 19)
Affinity DataEC50:  7.90E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29249(quinolinone, 20)
Affinity DataEC50:  2.10E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29250(quinolinone, 21)
Affinity DataEC50:  2.20E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29251(quinolinone, 22)
Affinity DataEC50:  4.10E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29252(quinolinone, 23)
Affinity DataEC50:  360nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29253(quinolinone, 24)
Affinity DataEC50:  500nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29254(quinolinone, 25)
Affinity DataEC50:  1.03E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29255(quinolinone, 26)
Affinity DataEC50:  2.90E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29266(isoquinoline N-oxide, 47)
Affinity DataEC50:  3.20E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29265(quinolinone, 35)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29261(quinolinone, 36)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29267(quinolinone, 37)
Affinity DataEC50:  3.40E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29268(quinolinone, 38)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29269(quinolinone, 39)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29270(quinolinone, 40)
Affinity DataEC50:  120nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29271(quinolinone, 41)
Affinity DataEC50:  290nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29272(quinolinone, 42)
Affinity DataEC50:  70nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29273(quinolinone, 43)
Affinity DataEC50:  97nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29274(quinolinone, 44)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29276(isoquinoline, 46)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM92900(L-Arginine, 2 | CHEMBL1835117 | NMMA, 2)
Affinity DataAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM130382(4methyl6{[(3R,4R)4{[5(pyridin2 yl)pentyl]oxy}pyrro...)
Affinity DataKd:  212nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM130383(4methyl6{[(3R,4R)4{[5(4methylpyridin2 yl)pentyl]ox...)
Affinity DataKd:  198nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  50nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of California Irvine

LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  30nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM29239(quinolinone, 10)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348711(CHEMBL1801475)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348712(CHEMBL1801476)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348713(CHEMBL1801477)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348714(CHEMBL1801478)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348715(CHEMBL1801479)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348716(CHEMBL1801483)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348717(CHEMBL1801484)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348718(CHEMBL1801494)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348734(CHEMBL1801473)
Affinity DataEC50:  4.30E+3nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348735(CHEMBL1801474)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348736(CHEMBL1801480)
Affinity DataEC50:  2.90E+3nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348737(CHEMBL1801481)
Affinity DataEC50:  990nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348738(CHEMBL1801482)
Affinity DataEC50:  650nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

LigandPNGBDBM50348739(CHEMBL1801485)
Affinity DataEC50:  690nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
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