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Found
12
Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-5'
Target
Neuronal acetylcholine receptor subunit alpha-5
(Rat)
Targacept
Curated by
PDSP K
i
Database
Ligand
BDBM50049757
((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
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Affinity Data
Ki: 0.0960nM
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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ChEBI
CHEMBL
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PC sid
PDB
Similars
In Depth
Date in BDB:
5/31/2012
Entry Details
Article
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PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-5
(Rat)
Targacept
Curated by
PDSP K
i
Database
Ligand
BDBM50079456
(TC-2429 | CHEMBL105374 | 2-Pyridin-3-yl-1-aza-bicy...)
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Affinity Data
Ki: 1.75nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/31/2012
Entry Details
Article
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PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-5
(Rat)
Targacept
Curated by
PDSP K
i
Database
Ligand
BDBM50047021
(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
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Affinity Data
Ki: 6.39nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
5/31/2012
Entry Details
Article
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PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-5
(Rat)
Targacept
Curated by
PDSP K
i
Database
Ligand
BDBM50171347
(A-85380 | CHEMBL190589 | 3-(Azetidin-2-ylmethoxy)-...)
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Affinity Data
Ki: 8.71nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/31/2012
Entry Details
Article
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PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-5
(Rat)
Targacept
Curated by
PDSP K
i
Database
Ligand
BDBM50004108
((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...)
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Affinity Data
Ki: 156nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/31/2012
Entry Details
Article
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PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-5
(Rat)
Targacept
Curated by
PDSP K
i
Database
Ligand
BDBM86309
(CAS_21019-30-7 | NSC_5311278 | Methyllycaconitine)
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Affinity Data
Ki: 200nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/31/2012
Entry Details
Article
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PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-5
(Rat)
Targacept
Curated by
PDSP K
i
Database
Ligand
BDBM50171341
(ABT-418 | CHEMBL188981 | 3-Methyl-5-(1-methyl-pyrr...)
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Affinity Data
Ki: 803nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/31/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-5
(Rat)
Targacept
Curated by
PDSP K
i
Database
Ligand
BDBM82546
(CAS_14721-69-8 | MCC | N-methylcarbamylcholine | N...)
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Affinity Data
Ki: 969nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/31/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-5
(Rat)
Targacept
Curated by
PDSP K
i
Database
Ligand
BDBM86544
(NSC_6442277 | CAS_192231-16-6 | CHEMBL111580 | SIB...)
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Affinity Data
Ki: 991nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/31/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-5
(Rat)
Targacept
Curated by
PDSP K
i
Database
Ligand
BDBM86543
(CAS_156223-05-1 | NSC_122225 | GTS-21)
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Affinity Data
Ki: 1.29E+3nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
5/31/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-5
(Rat)
Targacept
Curated by
PDSP K
i
Database
Ligand
BDBM50004656
((2-Hydroxyethyl)trimethyl ammonium chloride carbam...)
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Affinity Data
Ki: 3.25E+3nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
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Ligand Info
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ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
5/31/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-5
(Rat)
Targacept
Curated by
PDSP K
i
Database
Ligand
BDBM86241
(NSC_31762 | CAS_23255-54-1 | Dihydro-Beta-erythroi...)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
5/31/2012
Entry Details
Article
Copy Entry DOI
PubMed
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