Compile Data Set for Download or QSAR
Report error Found 59 Enz. Inhib. hit(s) with Target = 'NAD(+) hydrolase SARM1 [50-724]'
TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600605(US11629136, Example 36)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600583(US11629136, Example 23)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600584(US11629136, Example 24)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600586(US11629136, Example 24b)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600580((S)-(4-(Pyridin-4-ylmethyl)-1H-imidazol-2-yl)(thia...)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600588(US11629136, Example 25)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600590((R)-2,2,2-Trifluoro-1-(4-(pyridin-4-ylmethyl)-1H-i...)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600591(US11629136, Example 27)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600598((R)-1,1,1-Trifluoro-2-(5-(pyridin-4-ylmethyl)-1H-i...)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600571((S)-2,2,2-Trifluoro-1-(4-(pyridin-4-ylmethyl)-1H-i...)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600567(US11629136, Example 12)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600607((S)-2,2,2-Trifluoro-1-(4-((3-methylpyridin-4-yl)me...)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600561((S)-2,2,2-Trifluoro-1-(5-(pyridin-4-ylmethyl)-1H-i...)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600553(US11629136, Example 1)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600555(US11629136, Example 3)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600557(US11629136, Example 5)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600558(US11629136, Example 5a)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600560(US11629136, Example 6)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600608((S)-2,2,2-Trifluoro-1-(4-((3-fluoropyridin-4-yl)me...)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600562((S)-2,2,2-Trifluoro-1-(5-(pyridin-4-ylmethyl)-1H-i...)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600600(US11629136, Example 33a | (S)-4-((2-(2,2,2-trifluo...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600599((R)-1,1,1-Trifluoro-2-(5-(pyridin-4-ylmethyl)-1H-i...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600597((R)-(5-(pyridin-4-ylmethyl)-1H-imidazol-2-yl)(thia...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600594(US11629136, Example 30a | (S)-(5-((3-Methylpyridin...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600600(US11629136, Example 33a | (S)-4-((2-(2,2,2-trifluo...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600610(US11629136, Example 39)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600604(US11629136, Example 35)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600554(US11629136, Example 2)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600611(US11629136, Example 40)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600609((S)-2,2,2-Trifluoro-1-(4-((3-fluoropyridin-4-yl)me...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600606((S)-2,2,2-Trifluoro-1-(4-((3-methylpyridin-4-yl)me...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600556(US11629136, Example 4)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600559(US11629136, Example 5b)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600579((S)-(4-(Pyridin-4-ylmethyl)-1H-imidazol-2-yl)(thia...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600564(US11629136, Example 9)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600578((S)-2,2,2-Trifluoro-1-(5-(pyridin-4-ylmethyl)thiaz...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600565(US11629136, Example 10)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600566(US11629136, Example 11)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600568(US11629136, Example 13)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600570((S)-2,2,2-Trifluoro-1-(4-(pyridin-4-ylmethyl)-1H-i...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600572((S)-2,2,2-Trifluoro-N-methyl-1-(5-(pyridin-4-ylmet...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600575((S)-2,2,2-Trifluoro-N,N-dimethyl-1-(5-(pyridin-4-y...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600573((S)-2,2,2-Trifluoro-N-methyl-1-(5-(pyridin-4-ylmet...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600574((S)-2,2,2-Trifluoro-N,N-dimethyl-1-(5-(pyridin-4-y...)
Affinity DataIC50: 5.50E+4nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600563(US11629136, Example 8)
Affinity DataIC50: 5.50E+4nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600569(US11629136, Example 14)
Affinity DataIC50: 5.50E+4nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600582(US11629136, Example 22)
Affinity DataIC50: 5.50E+4nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600594(US11629136, Example 30a | (S)-(5-((3-Methylpyridin...)
Affinity DataIC50: 5.50E+4nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600577((S)-2,2,2-Trifluoro-1-(5-(pyridin-4-ylmethyl)thiaz...)
Affinity DataIC50: 5.50E+4nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600589((R)-2,2,2-Trifluoro-1-(4-(pyridin-4-ylmethyl)-1H-i...)
Affinity DataIC50: 5.50E+4nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

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