Compile Data Set for Download or QSAR
Report error Found 614 Enz. Inhib. hit(s) with Target = 'NAD(+) hydrolase SARM1'
TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776382((3R,4S)-4-(4-chlorophenyl)-1-(3-pyridazin-4-yl-1H-...)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776374([(3R,4S)-3-(4-chlorophenyl)-4-methyl-pyrrolidin-1-...)
Affinity DataIC50: 51nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776350([(3S)-3-(3,4-difluorophenyl)pyrrolidin-1-yl]-(3-py...)
Affinity DataIC50: 57nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776359((4-chloro-3-pyridazin-4-yl-1H-pyrazol-5-yl)-[(3R)-...)
Affinity DataIC50: 68nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776383([(3R,4S)-3-(3,4-difluorophenyl)-4-methyl-pyrrolidi...)
Affinity DataIC50: 72nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776369([(3R,4S)-3-(4-chlorophenyl)-4-(hydroxymethyl)pyrro...)
Affinity DataIC50: 72nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776348([3-(4-chloro-3-fluoro-phenyl)pyrrolidin-1-yl]-(3-p...)
Affinity DataIC50: 73nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776362([(3S,4R)-3-(4-bromophenyl)-4-methyl-pyrrolidin-1-y...)
Affinity DataIC50: 84nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776387([(3S,4R)-3-(3,4-difluorophenyl)-4-(hydroxymethyl)p...)
Affinity DataIC50: 93nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776372([(3R)-3-(4-chlorophenyl)pyrrolidin-1-yl]-(4-fluoro...)
Affinity DataIC50: 95nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776319([3-(5-chloro-2-thienyl)pyrrolidin-1-yl]-(3-pyridaz...)
Affinity DataIC50: 98nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM615974(US20230271957, Example 3)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM618465(US20230286978, Example 1)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 µL. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM616002(US20230271957, Example 6)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM615970(US20230271957, Example 2)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM616034(US20230271957, Example 11)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM616035(US20230271957, Example 12)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM616036(US20230271957, Example 13)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM618474(US20230286978, Example 10)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 µL. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM616037(US20230271957, Example 14)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM616017(US20230271957, Example 7)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM618468(US20230286978, Example 4)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 µL. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM618469(US20230286978, Example 5)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 µL. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM616032(US20230271957, Example 9)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM616033(US20230271957, Example 10)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM616042(US20230271957, Example 19)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM616038(US20230271957, Example 15)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM618476(US20230286978, Example 12)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 µL. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM616039(US20230271957, Example 16)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM616040(US20230271957, Example 17)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776326([3-(3,4-difluorophenyl)pyrrolidin-1-yl]-(3-pyridaz...)
Affinity DataIC50: 105nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776353([3-(5-bromo-2-thienyl)pyrrolidin-1-yl]-(3-pyridazi...)
Affinity DataIC50: 114nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776356((4-chloro-3-pyridazin-4-yl-1H-pyrazol-5-yl)-[3-(3,...)
Affinity DataIC50: 142nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776339([(3R,4S)-3-(4-chlorophenyl)-4-hydroxy-pyrrolidin-1...)
Affinity DataIC50: 172nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776351([(3R)-3-(3,4-difluorophenyl)pyrrolidin-1-yl]-(3-py...)
Affinity DataIC50: 183nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776355([3-(4-bromophenyl)-4-methyl-pyrrolidin-1-yl]-(3-py...)
Affinity DataIC50: 188nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776313([3-(4-chlorophenyl)pyrrolidin-1-yl]-(3-pyridazin-4...)
Affinity DataIC50: 191nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776335([(3R)-3-(4-chlorophenyl)pyrrolidin-1-yl]-[3-(4-pyr...)
Affinity DataIC50: 194nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776318({3-(5-chloro-2-thienyl)pyrrolidin-1-yl]-[3-(4-pyri...)
Affinity DataIC50: 194nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776377([(3R,4S)-3-(4-chlorophenyl)-4-[(1R)-1-hydroxyethyl...)
Affinity DataIC50: 196nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776379([(3S)-3-(4-chloro-2-thienyl)pyrrolidin-1-yl]-(3-py...)
Affinity DataIC50: 214nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776376([(3R,4S)-3-(4-chlorophenyl)-4-[(1S)-1-hydroxyethyl...)
Affinity DataIC50: 217nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM651662(US20240051939, Compound I-2)
Affinity DataIC50: 300nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM651661(US20240051939, Compound I-1)
Affinity DataIC50: 300nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776367((4-bromo-3-pyridazin-4-yl-1H-pyrazol-5-yl)-[(3R)-3...)
Affinity DataIC50: 340nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776330([(3R,4S)-3-(4-chlorophenyl)-4-hydroxy-pyrrolidin-1...)
Affinity DataIC50: 351nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776358((4-chloro-3-pyridazin-4-yl-1H-pyrazol-5-yl)-[(3S)-...)
Affinity DataIC50: 379nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776310([3-(4-Chlorophenyl)pyrrolidin-1-yl]-[3-(4-pyridyl)...)
Affinity DataIC50: 387nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776314([3-(4-chlorophenyl)pyrrolidin-1-yl]-(4-methyl-3-py...)
Affinity DataIC50: 427nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776317([3-(2-chloro-4-fluoro-phenyl)pyrrolidin-1-yl]-[3-(...)
Affinity DataIC50: 458nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
WIPO WO2025045746

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