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Report error Found 132 Enz. Inhib. hit(s) with Target = 'N(G),N(G)-dimethylarginine dimethylaminohydrolase 1'
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM92900(L-Arginine, 2 | CHEMBL1835117 | NMMA, 2)
Affinity DataAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM92901(ADMA, 3)
Affinity DataAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50138983(2-(S)-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50519933(CHEMBL4444007)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155523(US9011882, Table 1, Compound 18)
Affinity DataIC50: 3.30E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50389868(CHEMBL2070857 | US9011882, Table 1, Compound 16)
Affinity DataIC50: 5.10E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155517(US9011882, Table 1, Compound 10)
Affinity DataIC50: 7.10E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155515(US9011882, Table 1, Compound 8)
Affinity DataIC50: 8.60E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50565138(PD-404182 | CHEMBL595227)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human DDAH1 using SMTC as substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155510(US9011882, Table 1, Compound 3)
Affinity DataIC50: 9.90E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM34513(N-[2-(2,5-dimethoxyphenyl)ethyl]-2-(4,6-dimethyl-3...)
Affinity DataIC50: 9.90E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155521(US9011882, Table 1, Compound 14)
Affinity DataIC50: 1.05E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155519(US9011882, Table 1, Compound 12)
Affinity DataIC50: 1.10E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155522(US9011882, Table 1, Compound 17)
Affinity DataIC50: 1.18E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155516(US9011882, Table 1, Compound 9)
Affinity DataIC50: 1.28E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155508(US9011882, Table 1, Compound 1)
Affinity DataIC50: 1.31E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM46658(MLS-0254244.0001 | cid_17520 | 1,2-benzothiazol-3-...)
Affinity DataIC50: 1.32E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155520(US9011882, Table 1, Compound 13)
Affinity DataIC50: 1.34E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155514(US9011882, Table 1, Compound 7)
Affinity DataIC50: 1.37E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155518(US9011882, Table 1, Compound 11)
Affinity DataIC50: 1.41E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155512(US9011882, Table 1, Compound 5)
Affinity DataIC50: 1.77E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50626259(CHEMBL5437726)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155511(US9011882, Table 1, Compound 4)
Affinity DataIC50: 2.12E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Rat)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50240959((S)-2-Amino-5-[N'-(2-methoxy-ethyl)-guanidino]-pen...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of rat DDAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155509(US9011882, Table 1, Compound 2)
Affinity DataIC50: 2.33E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50240959((S)-2-Amino-5-[N'-(2-methoxy-ethyl)-guanidino]-pen...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50626258(CHEMBL5410984)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155524(US9011882, Table 1, Compound 19)
Affinity DataIC50: 3.99E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM155513(US9011882, Table 1, Compound 6)
Affinity DataIC50: 4.58E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50242402(4-Hydroxynonenal | 4-hydroxy-2-nonenal | CHEMBL454...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human DDAH1 expressed in Escherichia coli measured after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50070208(CHEBI:6375 | A-65006 | AG-1749 | Lansoprazole | Pr...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of recombinant human DDAH1 by HTS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50070209(CHEBI:8768 | Aciphex | LY-307640 | Rabeprazole)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human recombinant DDAH1 reduction in L-citrulline formation using ADMA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50254452(N-omega-propargyl-L-arginine | CHEMBL197234)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50254452(N-omega-propargyl-L-arginine | CHEMBL197234)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50255074(N5-(1-iminobutyl)-L-ornithine | (S)-2-Amino-5-buty...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50255074(N5-(1-iminobutyl)-L-ornithine | (S)-2-Amino-5-buty...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50254449(N5-(1-iminopent-3-enyl)-L-ornithine | CHEMBL456882)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50254449(N5-(1-iminopent-3-enyl)-L-ornithine | CHEMBL456882)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50626261(CHEMBL5434286)
Affinity DataIC50: 1.31E+5nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50254451(N-omega-(but-3-enyl)-L-arginine | CHEMBL106423)
Affinity DataIC50: 1.89E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50254451(N-omega-(but-3-enyl)-L-arginine | CHEMBL106423)
Affinity DataIC50: 1.89E+5nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50240714((2S)-5-{[(allylamino)(iminio)methyl]amino}-2-ammon...)
Affinity DataIC50: 2.07E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50240714((2S)-5-{[(allylamino)(iminio)methyl]amino}-2-ammon...)
Affinity DataIC50: 2.07E+5nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50626260(CHEMBL5438148)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of recombinant human DDAH1 expressed in HEK293 cells using ADMA as substrate preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50626257(CHEMBL364952)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DDAH1 using [14C]-L-NMMA as substrate assessed as reduction in [14C]-citrulline conversion measured after 1 hrs by by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50240716(Nomega-propyl-L-arginine | N-omega-propyl-L-argini...)
Affinity DataIC50: 2.83E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50240716(Nomega-propyl-L-arginine | N-omega-propyl-L-argini...)
Affinity DataIC50: 2.83E+5nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50254450(L-IPO, 13 | (S)-2-Amino-5-propionimidoylamino-pent...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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